Warren Buffet and Price History

By

Sampson I. Onwuka



zeistful picture of Warren Buffet.


There market efficiency arguments to be made about price history by many wonderful experts. The central key word for price history is management and result which Warren Buffet more than recent expert is firmly associated with it. We may suggest that he has also influenced management style in the last half a century in the United States and elsewhere. His style is world renown but is not exactly the best practice or do we state for sure that such styles are immune to failures and weakness or shocks from poor management procedure. But this is the point that price history matters, records of company performance matters, reputation in business matters but we can also state clearly that none of that is a deciding factor in real business exercise. We can suggest that management style may help individuals adjust to business interest and choice and this is closer to fundamental use of judgement than a general rule for deciding in any market.


It is important to reason for Dummy Variable is to navigate the market function in such a way that we deliver the psychology of wealth and human consumption from unrealized sentimental. It is not a motivation in the case to call this uniform theories of disequilibrium or a pressure to respond to the dynamics of a bear market shifting to a General Equilibrium or macro over micro. It will not also defend the idea that opposite which is momentum has bullish tendencies, or interacts between idea of changes in the market in real time or a flow, without a modality as pathology is the opposite of the fundamental or optimal requiring graphs and variables.


Each stage has its redeeming definitions – price and advantage and has losses and disadvantages, but disequilibrium is ultimately a personal pursuit of the remote sense of happiness and satisfaction and the market like most trading places determines the movement and not the companies. Behavioral economics gives a false sense of price which has no history and for that reasons fundamental market movers second guess market momentum. If I should challenge some of the assumptions in Warren Buffets intellectual currency that price does have history, I may begin by pointing to the levels of market expectations and perhaps the NIARU – even at undetermined appreciation level.


In point to the same fate and argument made by Benjamin Graham and in recent times, Warren Buffet, the systematic induction of price movement as a function of human decision, exist only on certain level. The level is not very obvious as far employment rates are concerned, or as far as quantity is concerned, the level is operational dynamic of entry consumptive data indexing and somewhere in the middle management where quantity and duration pamper some of the risk factor and momentum. In some sense, price becomes subordinate to history and to fundamental coercion of quarterly and periodic earnings when there are obvious dissolution of white noise or signs of indigent reaction of the total carrier to external or internal shocks to the system.


At the level that Buffets refers to, our expectations of total economic package and returns on investment based on daily movement and revert flow to stochastic (stock), size and quantity becomes important. A sizable of the proportion that Buffet operates with and perhaps Graham, makes price and cyclical economic returns very important, given the tendency to insulate momentum by stretching the expectation to less 5% or less cumulative profit.


 The financial polar tug and gravitas to earning rates at that levels is usually poor informative procedure given the size considered. We can add that the study of the risk factor involved is to closer to balancing of equilibrium or uniform convergence to equilibrium – a bad thesis for market impetus leading to general equilibrium or what constitute oversight under micro-management. Size does matter in deciding the history of numbers, does not mean it is correct, does mean that size of investment in so far a linear market is concerned or one industry as the case of tier 1 and perhaps tier 2 without the distinct issue or role of money supply-, size can move any market at any time to a specific direction forcing momentum even without the convexity bias of less than zero or the skewer (skewness) distributed with less on perhaps diffusion rate over duration.


Size can also diminish the ability to move mutual funds from real estate or revert to gold on earliest signs of fluctuation – which is behavioral – to some extent irrational as opposed market decay which are changes in elastic constant over a 9 year cyclical economic long term.


There are stages of these development and generational pathology and it applies not to the companies in a sector – age of the sector but also the political age of the economic community whose instability is usually a false justification for actions primitive to accounting and corruption which is the bane of most societies. Showing the duration of some companies operation in any industries may be important information in determining what may or may not be a controlling factor in brokering a study in specific industrial sector of any demand and supply. PIMCO removing their investment vehicle from U.S bond market may be tactically induced by financial institutions, no less purported to Lehman and Bear Stearn with view of stimulating stock market or cast aspersion on IOU as efficient market position reverting to gold. Federal Government usually throw money out there to the banks during emergent control problems of momentum to forestall skidding and kurtosis and enable size and economics of quantity as item to helm fluctuation reducing the momentum and panic in the global market.





Peter Phan (2015)---writing for Forbes on Warrent Buffet favorite book ‘The Outsider’ a William K Thorndike (2012), describes the importance of records in the life of a company and the practical exercise of Berkshire Hathaway. That "Warren Buffett is better known for investing in companies like The Coca-Cola KO -1.04% Company and GEICO, which are heavily covered by the markets and the media. Unbeknownst to many is Buffett’s deep engagement in entrepreneurial activities that provide seed capital. In today’s businesses, a CEO plays a vital role within an organization. From a valuation perspective, their strong track record will drive market confidence and make the company more attractive to investors." As such tract record to price history is commercial interest for mounting investor confidence.


If investor confidence is reach by numbers and consistent delivery rate, the numbers add momentum is sufficient to ensure that rating from primary and secondary sources are relevant. 1% is to important to ignore but junk bonds for practical real time investment is discount for larger return, to bond rate perhaps risk averse. Preferred (Prebend) attraction for exceptional stocks (that is companies in nose-dive) allows a different argument by Warren Buffet to prosper for reasons of debentures or above the market price (usually below) with new and defunct companies as target practice.


We can still argue that ability of any company to adjust to momentum or return to normal distribution following shocks to the system, excise the strength of the company or performance of the management. It is also a exercise of a company’s competitive advantage. But profit is by default on the argument that company’s yield is based on the shortfalls in other companies especially big companies that were mismanagement. Efficient market hypothesis.....


In a sense, understanding a tendency to abbreviate or gauge what happens to a specific interest item or study – gives us a hint of one’s pathology – does not mean that an emphasis on history is prove that an expert is looking at what happens to fundamental changes in the market and why it does. To obviate that the intellectual ancestors of market makers were chartist or bond’s men perhaps with graphs to burn in, may influence attitude to market apps - it may seem to show the age of the brain involved (experience), may explain the gap approaching the reasons why some experts emphasis summation or reduction and why they defends the assumptions that a process or strategy needs to be defended to a point of apathy – show signs of sentiments or overall strategy and therefore in appropriate in accessing risk value.


We can consider the use of dummy variables as a means of overcoming sentiments which show up every now and then. The question about market price and history, explains the limits of market exercise that compares the past to the present, as way to broker the future in spite of changes in world market. A 2008 symposium is a false entropy although the ‘taste of the pudding (purnice) is in the eating’, Warren Buffet ability to offset some of his companies and re-alternate his preferred shares in certain major Banks – Wachovia to mention – is an exceptional candidature and probably not the norm. The veracity of price over history – vice versa – require larger platform but it is important to note that even fundamental shocks and sentiments in the markets which is enforced by records may reflect more troubles with a company and the market blinded from easy operators. Although the Lagrange officialdom on transmitting the limits of linearity of economic models to disequilibrium explains General equilibrium.


That Jevon to the left sided materialist such as Alfred Whitehead, some of the examples in the history of mathematics and reduction of intelligence to basic and adulterated formulas, explains the age of the cultural history, the size of the industries and the persons on interest who we call the intellectual ancestors. A proof to show course is a legal as well mathematical indicia of prosecution that a Roase as open to Coarse would divide to alter that in law in art, the rule of logics is reduced to numbers – each an items of process explaining perhaps a period.


We look at the decision of most economists to use dummy variables to widen the scope of tables as a form of pathology that entails as much problems as the first men and perhaps women used pebbles to organize house management. It does not appeal that a poverty in Gaussian mathematically models diminishes a Movier (?) over Paschal on the limits of probability, or does it shy from the weak arguments on recent market hypothesis in names of Fama and in deeds of Black.

Robert Sapolsky akin to Robert Plomin to halle 'Alzheimers' to Speech and Dementia

By

Iroabuchi S. Onwuka


These two men probably need introduction but their work do not.

Robert Sapolsky


Robert Plomin

By

Iroabuchi S. Onwuka

My interest in the general theory of protein and the plaque on the brain that block some of the receptive life streaming between the medulla and cortex started with Robert Plomin. Although some of his theories have high Darwin absorption rate it looks to narrate the development of human cells along the nurture of one’s environment. The issue is not the effects of environment on human intelligence but the extent some of the genes in the body proclaim the audacity for academic ability. There are so much we can narrate from the issue of nurture and nature and one predilections of one’s environment, but to the extent that the environment s and human consumption of energy are experienced in the body troughs specific pathways, nurture and nature and the adaptive procreation of human beings from plants and plankton to microbes that eat green algae to prokaryotes adapting to living on the surface of the earth until the worm-like organelles – the Eukaryotes may explain the nature of experiences and human senses and how they reflect our lives proving a curative. One of the greater importance of the life and growth of cells into full adult forms is the power of the brain; especially the function of the hypothalamus is handling the environmental reactionary – for instance the natural constants such temperature and pressure – and its envelope effect on the release of hormones from the body are controlled by the brain. The brain therefore forms the backlog of human understanding and the biological evolution and it is considered from more ancient past sacral due to its ability to perform very practical function of the body.

The question of the brain with redundancies sorted by the cerebrum is the fact that proteins can be treated to avoid the gradual death – perhaps through a cystic autoimmune deficiency and accumulation of hormones that depletes another, or hormones triggered into bad actions or poor timing due to failures of the hypothalamus to regulate the body hence ousting bad timing. The next important aspect of sensory receptor cells and is the role of LTP; long term Potentiation, by which ‘a synaptic model for learning is the process of stimulating a dendritic spine in a dense cluster of rapid action potentials, resulting in that synapse becoming hyper responsive or potentiated’ and ‘after potentiation has occurred the pathway is stronger’.  In all likelihood, potentiation is that probability that one neuron can cause action potential. and mentioned the ANS (Autonomic Nervous System) and PNS (Parasympathetic Nervous System), where the voluntary nervous system controls as it where for many cases involving both sides of the information that ‘Voluntary Nervous System’ which controls rapid regulations of skeletal muscles. So he described plasticity in ANS function as condition made possible for three functions (a) habitation (b) sensitization (c) biofeedback, all of which are part of the parameters of ANS.

The third plasticity is the ‘Biofeedback’ lope, which Sapolsky described as a “conscious tool for controlling the unconscious workings of the ANS; for example, thinking relaxing thoughts can reduce the SNS responses.” For instance Chocolate contain ‘Phenylthalamine’ (PEA), which is visible and noticed in large amount for people in love, especially women, show that the long held view that chocolate is the food for the soul, may have some chemical reasons for it. In essence love or the feeling of being in love can be forced by the intake of a ‘PEA’ brand. This area more than anything involves the new attempts at evolutionary behavior of human psychology.

Arguing from Robert Plomin’ hypothesis, this was gene or what they ‘accurately’ mention as allele, was found in the ‘Chromosome 6 and in an insulin-like growth factor-2-receptor’, and Plomin it is argued, collectively grouped this set of genes as ‘IGF2R’, and ‘two forms or alleles were examined known as allele 4 and allele 5’ that it was believed to have been involved in neurophysiology of the brain and the functions were not well known. But from other sources, the structure of human brain significantly differ from the Chimpanzee and other Homo-erectus, and from instance mentioned here and in the relation between the Insulin-like gene no doubt relative to other sugar control genes like the ones the humans cannot produce; Sialic Acid, seem to suggest a relevant relationship to dope or similar enzymes that are linked to B receptor cells. Although Matt Ridley independently mentioned that the middle IGF2Ry of Plomin containing 7, 473 letters are mostly found in Chromosome 6 which is he called intelligence gene of the total 98, 000 letters. Merck ‘TSA, and TAAs typically are potions of intracellular molecules expressed on the cell surface as part of the major histocompatibility complex’, host response to tumors constitute its cellular immunity, biology of the immune system constitute its cellular receptivity. “Any auto-reactive lymphocytes not controlled by these mechanisms are usually restrained by FOXP3+regulatory T-Cells. A regulatory T-Cells defect may accompany any of these mechanisms for autoimmunity. Anti-idiotype antibodies (antibodies to the antigen-combining site of other antibodies) may interfere with regulations of antibody activity”

Robert Sapolsky in one his teachings on ‘Biology and Human behavior’ showed how the connections between the Cortex to the Limbic is physiological displayed in the brain function, such that Frontal Contex shows a connection to the Amygdala to the Hippocampus, from what they called the hippocampus to Formix to Septum in a short attempt to translate information – especially sound to the brain illustrated through the Hillocks. The impact of sound on human language is a long story of sound and memory that separate the structure of the animals from one form to another, perhaps the human brains so wired to understand and analyze sounds is based on the brain where the frontal cortex or lobe is as protruding as perhaps human closest primates. It is easier to make the study that connection of the Thalamus to Hypothalamus is biological, entails sound and perhaps speech entails attitude to things about us than others that the other sensory nervous system including temperature and pressures which are part of the brain’s memory are not taken seriously. Whereas the argument is entirely useful that majority of what the fibers of brain protein retains is closer to sound than temperature – for instance the dermis of the protein walls and the sodium gated channels between the ions and solute below the two layer of cytoplasm is based on sound – more to sound than temperature – since sound parts the gated channels encouraging the reproductive quality of APO-proteins. But it is really the temperature that serve this purpose not necessarily the final versions of temperature which is sound exist the axial stage of zero or neutral stage. We can sum up the relationship between heat and temperature to sound and energy as a consequence of light and coloration defining the age of the sound and the perception which is a differential so to speak of relative response of the body to new sound and experience. So between the Thalamus and hypothalamus through to the Mammillary Bodies are question of transition that enables the body and the brain to perform their function through the right process and processes of information translation.

A Negative Feedback loop is a term that recently achieved field theory, commonly used in the relation of the small quantity to the original body. My oldest knowledge of the use of the negative feedback is used by Harold Stephen Black considered an engineer. But the double negative feed gives us a better picture of human memory which is a relay process and deals with human synaptic that age with levels of receptive ability. In small inlets, the rate a breakdown takes in the body is not different from the way the body analyses its information. This process however breakdown as we age and the rate at which we are aware conformed by return of negative message – message since it detonates a parts of human brain most reception to a system entering the medulla on which the hormones stimulus is most effective. Without this negative feedback essentially returning a sound, a voice as with dermis to another to major domo, the color that separate the information and elements will filter different and the brain will not distil () and we remember the past not the very present. In one offs beat argument, there is something about the relationship between what we remember and here, Alzheimer is important in Medicine. How we react to information and is perhaps related to speech, behavior, and what they call the frontal loop but it is really a matter of the body ability to handle specific nature of information. An excessive form of the informed reaction may be taken as dementia, but really the ability of the body to project an experience is more to do with frontal loop not necessarily what we consider a re-collection.

We shall cite an example on how the language and human sounds pave and close means and ways the bother transposes itself and why the theme of logic and speech permeate the very knowledge of human body. It is an example that paves the way for understanding the brain diseases and conditions, where the impact of information system to any part of body and to the simulation of suppressed emotions and enzymes and sex hormones can suggest that a recommendation of the use and abuse of a therapy, sexual therapy, sensitized neuropathy and above all the culture with charged sexuality suppressing these emotions differently. Free Nerve ending have no “preferred” mode, it is stimulated without a preferred mode and in various other ways, it is equally responsive equally responsive to chemicals, temperature, damage to the tissue, electricity which is recent addition and radiant energy.

The Cochlea as we shall also discuss will open several arguments about the ‘tick’ or ‘clicks’ of sounds in the ear and how the brain interprets it, why it was successfully perfected by Hungarian 1961 Nobel Prize in Medicine and physiology, Georg Von Bekesy, ‘for his discoveries concerning the physical mechanisms of stimulation within the Cochlea’. Georg Bekesy is not the first to perform such experiment about auditory canals but the field was quite revealing of the internal dynamics of the hearing system and not necessarily its storage capacity. His work which has led to the production of artificial Cochlea as part of the sensory prosthesis –where such devices as ‘Cochlear implants’ and ‘retinal chips’, which are small devices that look like the ear can now aid the hearing faculty of the patient.

So the outline of the brain in terms of the hearing capacities is as follow, (1) Cortex, (2) Limbic system, (3) Hypothalamus (Brian Stem), (4) Pituitary Gland. We are not very excited about with medulla oblongata or the cerebrum at this particular point, we are primarily concerned with the Cortex and the Limbic system, largely for the function they perform in helping to create a living and explicable pathway for hearing and for other forms of human device, and in multi-faced forms of storage and memory. So we begin with the Cortex. The Cortex is the part of the brain’s evolutionary structure for learning and absorption and the work of the six layered parts of the Cortex is fairly notable in Biology. We doubt that the specific function of the Brain layers is subordinate to memory and learning only, but the forms of expression that accompany such learning one hand and storage ‘memory’ on the other, compels other reaction in the large swaths of human life and its existence.

Sensory Physiology involves the study and the dynamics of how the brain connects from the outer limits of the world of information to the inner parts of the brain, a process it achieves by series of ‘interface’ or series of interconnection. The purpose of understanding the physiology of senses is that it shows how sensory receptors (cells) work to translate energy states into information that the brain recognizes, a case not too far from biophysics and in the words of Francis B. Colavita of University of Pittsburgh, sensory “Cells that change electromagnetic, mechanical, chemical, or thermal energy into a form to which the brain is responsive.” These cells translate forms of energy or states, in such a way, that receptors define our sensory world and how perceptions “created in the brain by integrating basic sense data with our past experiences. Past experiences stored in the brain give meaning to our present sensory experiences.”

It is also clear that no particular group of human primate can eagerly state for such to suffer deficiencies in any of disease than others. If we care to add at this point and in extensor, the recovery rate of body to any induced influences describe the nature and necessarily nurture of the proteins and the genetic we are saved from the arguments. Saved from the arguments is the reality which we impose from elsewhere that gorilla’s tend to higher cortisol level and steroids than most other primates, that whereas human have degrees of the blood types of the classic version of A, B, and O, is lacking in gorilla and Chimpanzees with only specific blood types. The contentious issues is the copious separation of a peculiar brain condition – the Dementia closer to the frontal cortex and the place of frontal lobes which is a final protein products of a blood deep in valines, two valines stymies’ depression tendency, show high levels of clearance of cortisol and a versed version of cortisone – steroids and hence slightly immune to depressive chemical imbalances of valines in the demine of a specific enucleated blood type. The other aside of the dementia – and the in the case is the plaque of composition in the nerves and protein walls of the brain, that is the Alzheimer is no less a condition respective to the slow translation of informed exposure than the ability of the running ‘fibroins’

Saunders, A, M, W.J Strittmatter, et al, 1993 “Several independent line of evidence led us to examine apolipoprotein E in later onset familial Alzheimer’s disease (FAD). We observed several proteins in CSF that bound to immobilized amyloid-beta-peptide (found in AD affected brains) with high affinity. Micro-sequencing and Western blotting technique identified APOE as one of these proteins. APOE was known to be localized to the region of Chromosome 19, which in previous studies had shown possible linked to onset FAD. Furthermore, antisera to APOE stained senile plaque, neuro-fibrillary tangles, and cerebral vessel amyloidal deposits in AD brains” The subject of recent experiment Robert Green is based on the reproductive ability of APOE and how it can enhance the the warning signs of Alzheimer. If you take the case very seriously, the informed 

Weiner, Shulman, et al, @2003, “Signals are relayed from one neuron to another along the neuron’s long fiber, called the axon.” That at “...the end of the axon, the signal flashes across a space between the cells called the synoptic cleft. The signal then activates the next cell, which carries it along the axon to the next cell, which carries the signal along – so on.” These informed pathways gives us fare idea on how energy is processed by the body and how the gradual failure of the brain and mind is linked to neurons and the adaptive tissues. In considering the failures of body and brain to defend its against Alzheimer there are degrees of failures. Naturally the assumption is the tissues and axons poles may be responsible for the deficiency in information, especially in relationship between the races - the rate being the worse in human races with European and North Atlantic background. But this is not perhaps the case - the case is that the plaques and tangles in Alzheimer may have a lot to do with blood types and ability of remove hard to digest enzymes and chemicals from the body.

“The brain is divided into three main sections; the two cerebral hemispheres (together known as the cerebrum), the cerebellum, and the brain stem. At the base of the brain are two large groups of nerve cells called the basal ganglia, which are made up of the Putamen, the Caudate, and the Globus Pallidus. The Putamen and Caudate together make up the striatum. The basal ganglia are intricately connected with almost all other regions of the brain, and they play a large role in modulating signals for normal and abnormal motor activity.” 

 

“The Substantia nigra is full of dopamine – producing cells, which deliver their product (dopamine) to the basal ganglia and other parts of the brain. Because this path for motor control includes both the substantia nigra and the striatum, it is called the nigrostiatal pathway.”

‘When the substantia nigra is damaged and the dopamine cells malfunction, the Dopamine supply to the canduate and putamen (the straitum) gradually reduced until eventually, the symptoms of Parkinson’s disease emerge – generally when about 50 percent of the cells in the substantia and damaged.”

When these do not function very well, there are instances of Parkinson. Senile dementia “A relating common condition affecting the elderly (sixties and older), caused by cerebral arteriosclerosis”

“Accepting Alzheimer’s diseases as a separation disease prevented the coming about of another, more complicated question, i.e., the question whether Senile Dementia is a disease entity to be distinguished from aging.”There are cases of cortical dementia, severe memory loss and subcortical dementia – affecting people – language difficulty (1) Parkinson’s dementia (2) Huntington’s diseases (3) AIDS dimension and other versions of multi-sclerosis. Nerve cells called neurons linking the ‘brain’ spinal down to muscles of hand, information ‘relayed’ from one nerve end – neurons to another – through fiber – (protein fiber – (wand) ) axons. A case in time concerning the Americans who suffers the accelerated versions of the Alzheimer disease beginning with the questions of MCI – Mild Cognitive Impairments….Sections of the brain…..(1)   Speech – frontal lobe (2) Thinking and Attention – frontal lobe (3) Sensation and movement (middle part of the brain) (4) Perception and Broca – following the middle part of the brain (5) Vision – back of the brain (6)   Balance – suffer a blow to the brain (7)    Emotion and memory – very lower part of the brain.

We use Robert Sapolsky’s explicating to detonate why the plaque in the brain is not so much a question of the cancer which is really cystic and the slow rate of the body to remove from medulla and oval patina of cerebrum ingestion pallets of calcium which hardly run the course with iron as a regulator or inhibitor for calcium in the blood. The blood issues regards to Alzheimer’s is plain in how the sickness may be generic, plain on how the diseases or the gradual breakdown of the nucleated member pertains to motor neuron and the its feedback potential, whereas those which accompanied versions of brain decay which is not Alzheimer’s but a sudden end capable of meeting any nerve at human ends. The issue of poor removal of calcium from the body be based on the generic struggle of one’s blood types, to an extent we can cite that the possibilities of a monkey with especially blood types suffering Alzheimer’s may differ from the human and a race to its tilt. Apparently we need describe in short details and for the interest of human cancers or cystic inducement of certain hormones in the body that may fail to function narrating the rundown of sensitive chemical repository in in the body, may explain its origins in the composition of the body and blood types.

He mentioned that in terms of ANS ‘sympathetic nervous system releases (SNS) epinephrine and norepinephrine (adrenaline and noradrenalin) is used’. The Parasympathetic nervous regulates the blood. So parts of the Neurotransmitter involves a long chain of action potential that are located somewhere in the brain and in the cortex and each of the three major plasticity in ANS function are a final look at the brain and how it functions in the main. The ‘habituation’ which relates to the process ‘whereby the same stimulus will not have the same effect on the ANS’ can better be described from the stand point of what happens in the young level of newt, the ‘sensitization’ is the process ‘whereby a stimulus that once did not have an effect on the ANS now does’, relating in part to same theory regarding the same possibility of the brain acquiring new synapse strength, were the idea of motor neurons of say a man or woman, who was essentially blocked in the motor neurons of the brain, who naturally would act and feel anything since the trigger and information storage is missing, may be a temporary and short term incident and by that the major neuron affected is the hippocampus.

The short delivery ration of information trigger is at the time of the choking blocked from learning new things, making it seem that the brain will not function. Apparently, the brain gradually picks up and heaves information and new synapses unto of the older ones, suggesting that after the sensory cells, the damage is common and may have temporary effect, but it is one of the cells that can repair at a much faster rate than others.

The SNS responses connect one very close to Parasympathetic, for that the human response to certain drugs in quite important since it enables the body to regulate the range of its emotion and to some degree expression. One example that appears in several text books which Sapolsky also mentioned relates to the dry quality of ingested drugs. It is said that some drugs when ‘ingested dry’ can enter into the ‘blood stream’ ‘enter the brain’ get into the synapse largely because the dry has similar chemical structure identical to Neurotransmitter. But other drugs can also produce the same effect by forcing the neurotransmitter into a long chain of action. For example the hallucinogen such as LSD, Mescaline, can stimulate the ‘Serotonin receptor’. And still in terms of SNS, some drugs can block information, for instance ‘Curare can block the acetylcholine receptor in the diaphragm causing breathing to cease’, cocaine of course trigger the release of dopamine hence people act weird and fearlessly. And on the other ‘Antipsychotic drugs’ can block the same dopamine receptor, weakening or ‘lessening symptoms of Schizophrenia’.

The ultimate issue about the SNS and Parasympathetic, It is no surprise that in 1949 he shared the Nobel Prize in Medicine and Physiology with Egas Moniz, for “…his discovery of the functional organizer of the interbrain as a coordinator of the activities of the internal organs.” The powerful contribution of this two is in terms of ‘Viscosity of Blood’ and ‘squint’, led to further conclusions about ANS; the autonomic nervous system. Walter Rudolf Hess describing his work mentioned “In contrast with very extensive…investigation of the vegetative (i.e., involuntary or autonomic) nervous system, there existed relatively limited knowledge of the central organization of the whole regulating apparatus….It had nevertheless become clear that…the parts of the brain joined from above directly to the spinal marrow – the Medulla oblongata and ‘the portion lying immediately under the cerebrum, the so-called interbrain’ - exert a decisive influence on the vegetative regulations….(Something was known in this connection of the function of a group of nuclei at the base of the brain referred to collectively as the hypothalamus). That “The autonomic nervous system is divided into two parts; the sympathetic, arising from cells in the thoracic and upper lumbar region of the spinal cord; and the parasympathetic, arising from cells in the mid-brain, the medulla oblongata, and the lower, or sacred, region of the spinal cord. .

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A collection of Wedding Pictures at Newton White

Chigozie and Michael - Maryland




 

















 @Newton Mansion




Helen and Joel's Wedding @ Newton White Mansion @ Laura Elizabeth Pohl.



 Scottbey picture @ Newton White


@ Newton White by Amy Deputy

Joe Biden and the Legacy of Obama

By

 Emily Atkins
Sampson I.M Onwuka 




 AP/Molly Riley - Joe Biden @ Rose Garden



'Vice President Joe Biden is not running for president.'


Since the announcement by Vice President Joseph Biden that he is not running for President, the Democratic party has perhaps taken a different look and the gap which the decision may have opened does not seem important.

How strange that the majority of Democratic saw the Vice President differently, how different? is how he would likely fit into the return of Hilary Clinton to seek one mandate she longs for.


Emily Atkin writing back from Washington describes the moment that "Standing in the Rose Garden at the White House on Wednesday, flanked by his wife Jill Biden and President Obama, the vice president cited lingering grief over the his son Beau, who died of brain cancer this past May. As he moved through the grieving process, he said, the window had closed on “mounting a realistic campaign for president.”


There is hardly anything to celebrate about Biden's decision but in the interest of argument his chances of winning are not articles for public press. This does not mean he is not capable and seem to suggest that he is unaware of his own popularity. 

In his brief announcement he backs Obama administrative records, perhaps a coy that his administration gave women a chance, vouchsafe that it was worthy to part with such legacy. 

“Our nation will be making a tragic mistake if we walk away or attempt to undo the Obama legacy,” That the “...American people have worked too hard, and we have have come too far for that.” (Joe Biden) - does not mean that he is creating a path for a formidable political machine, but he is practical that his chances are also slim.

It does not mean that Biden is political off the radar, perhaps a searching interest in a year of reflection nudges him and his advisers to throw-in a Presidential tower.

For a fact and perhaps for reasons not necessarily good for the press, not all politicians of interest enjoy spot light, which does not mean that Biden is far and above any hint of publicity stunt.

Perhaps the expectations of a White House is written in his character and perhaps in his interest. But there are others running. His political numerical advantage may have to pose against Obama legacy which was necessary to prove himself.

To a fine degree that his candidacy did not really appeal until the announcement, we could suggest that the decision was calculated.

If Biden fondled any hopes of a presidential ticket his sit tight position is not for a son or others, he is perhaps impressed or unimpressed by early campaigning which the uncertainty of early announcement has not been fully known.

Land Economic - Harold Black

Detroit ; A case study in Industrial problems of a Central City by Harold Black 219 – 226 pages of Land ; 1958,  - 948-2009 (Vol. 24, No. 1 - Vol. 85, No. 4), writes about the methodology involved in Industrial Study based on the responses from 4, 000 industrial firms within the City of Detroit.

I move to complain....


948-2009 (Vol. 24, No. 1 - Vol. 85, No. 4)

Review

By 

Sampson I.M Onwuka 

Information generated here was carried by Michigan Employment Security Commission and Research Committee of the Detroit Metropolitan Area Regional Planning Commission, revised along the Milwaukee Junction Manufacturers Association concerning resources allocation and appropriation. Harold Black is suddenly important for a study on Detroit and its use of land during the specific era of Ford expansion and automobile industries trapped between worker residence and the rapid expansion of urban Detroit. The period has the most tentative issue is the years following WWI and here the author placed special emphasis on the issue of rail vs. trucking service and delivery, pursuant to the dissent of Manufacture vs. Land Resource. Although the conservative nature of U.S Inter-state and commercial laws, especially in estate domain took active direction from 1900 - especially in Chicago and New York were supreme court of the United State direct hit and interest, we assume with regard that here and perhaps elsewhere, that there are problems of Special Impact Zones which the City Planners over the years struggle with exceptional interest on housing with momentum rapier than rural and residential cities in the United States.

The issue of Land Economics is for far household Management is concerned is a long as world history but in these United States, we align with Harold Black in considering specific eras in American landscape with appropriation rate to residency to factory or in some case a consideration of production capacity to manufacturing, the later combined from factory to house capacity for leaving, part of the human macro condition that factory that sometimes dovetail special cases of government intervention or privileged invention. Domesticating major interest areas in U.S is a point in one direction, transforming Urban Cinderellas to Cinema Montage in spite of the growing population is long term priority. Here Harold Black assemble some percentage shift in land use, that (1) Prewar War I (before 1914) – 17.4%  of the land in Detroit were reduction fact for industries (2) By the end of World War I (1914-1918)  through the Post World War I (1919 – 1930) – there was a grasping of 29% of land shift (4) Through Depression (1931 – 1935) was additional 4.4% (5) Following the end of the Pre-world War II (1936 – 1940) -10%  and through World War II (1941 – 1945) – 10.3% were rendered company property (7) The major problems began to show after the First Postwar Period (1946 – 1950) – with 13.8% disuse (8) By the Second Post War period (1951 – 1954) – with additional 7.5% appropriation, there was hardly enough land to industrial giants comparative.

Contrary to what was believed to have taken place at the turn of the Century with the influx of African Americans in Detroit - so to speak - we may safely assume that the shortfalls in vetoing percentage among other Americans to African Americans, to the shortfalls in healthy living condition for European Americans in Detroit - may or may not have prompted the decision of the Federal Government to accommodate the credit of many well to do industries. This may or may not have created the demand for investment and courting of safe currency in particular hue for departure into Rural areas than Detroit. We may assume that this blow which Detroit suffered was not a natural course of most Cities, it was an unwholesome development that neglected the issue of Land and its economics.

We take it that the adequacy of land facilities – given the expansionary plausibility of City Town such as Silicon Valley or a placement case for factories in Detroit displaced 30.1% needed 548.4 acres of land, each likely a sub-diction of 1.7 acreage per company explains the veracity of Land Provision and a reverting to transformations of City and its resources under the very active human or industrial eras. Although the period we are looking is late in the august temple of 50's during the vast interest in automobile, we look at the author differently from a perspective other factory expansion in singe linear cash crop environment, to use of land and appropriation during high points of human migration to several cities in the United States - in this case - perhaps Austin and perhaps Phoenix in comparative assuage to Detroit and Chicago half a century ago. Stated clearly and in respect to Detroit, Harold Black mentions that “The urban land institute studies of modern plant practice indicated that 6 out of 10 plants have employers per acre.”, a point that was serious in how the human migratory expansion in Detroit created a pull and then implosion before the end of the 60's.

“The Median for the City of Detroit is 69.3 per acre. Almost three Quarters of all the plants replying to the survey had an employee density ration of 40 or more workers per acre.” So shortage of land led to oversupply of workers and there was the discussion on the problems of allocation and utility. It seems here obvious that the expansion of 1920’s Fords and the 1936 apparel manufacturing in many part of Detroit was an economic consequence of the era and ended in light in the of the competition of this period in the history of the United States. We assume that the (1) Food processing, textile and apparel manufacturing; printing chemicals, rubbers, stone, fabricated metals; primary did better given the new age technology at this period in the world of economic and finances and in the United States as these assumption will prove and it is quite understanding that the measure of lands and search for land use and allocation is course of Development worthy of the greatest measure of discipline.

(3) Adequacy of Transportation facilities, 9 out of 10, employees of the surveys manufacturing came by road packing space and after sometime, there was hardly any place for packing space in the Detroit and in neighboring towns and cities. Some estimate reflecting this period suggest that the deficit of 50, 000 spaces for manufacturing concerns for corridors and for packing reduced the available space for the city and for other interesting posture in the event of the expansion and the history. To the enabled degree that a standard 320 acres, per space of 400 shortages (4) Mobility of Industry. At the tendency to relocate was due to ‘can large portions of it, based on investment and other commitments, “For example, in regard to the movement of industry, 97 plants which were on the mailing list to receive the questionnaire were found to have moved out of the City.” That is 1953, 97 industrial plants had moved out of Detroit and taken with them a combined 8, 809 workers, many of them had no plans to return to the City of Detroit.

Detroit recovery may be reduced to the role Banks and especially a State or preferably City Reserve Bank, which should help to stem the two roles performed by Banks. As we know too well, Detroit’s demographic expansion is based on a number of important things, one of which was the cheap access to buildings and easy-time Credit expansion, first for the Whites themselves and then others. The long history of the segregation in Detroit is historically born out of the struggles for Appalachian West, which started with arrival and eventual settlement of Antoine Cadillac on the Ste. Marie and West of Huron. Apparently, the Indians fought back during the time he was there and when he left the place, the Indians resisted European expansions.

Of course it may seem that the Port was either not paid for or that the opening of the area was with the help of Cadillac and the Indians, but natural confrontation over owns what led to series of confrontations between these groups, adding the sparing of Blacks from Canada by Indians and killing of Whites or Europeans when found. At least 1837 as the date the Michigan became part of United States is a watershed, given to the reasons that Indians and English warred for some time and Indians warred with the French, then switched sides with English against the French all of which came to an end in America by the coming of the U.S Army. So these warring groups of Europeans ended making peace but the price of the peace was the collective blood on either sides of the tribes of Michigan, especially the Indians and the Blacks who reduced to hundreds.

In essence the conflict was one of youngest in history and it is ached into the memory of those who saw THE Civil War and the threat to the country. The late amalgamation of Michigan into United States in 1837 coincided with the end of Slave era, and with that, the area in Midwest did not emancipate from Slavery to what others celebrate, it witnessed the rise and challenge of elite class and then Blacks and others, some from Canada with no hint of brass of their ancestral legs and therefore sought their own means within miles of the European migrants. This created a rift that did not heal at all, since Indians returned and returned to Michigan and mostly from Ohio to plague the inhabitants of most Europe brocade, it led to standing militant armies, and this lasted till the beginning of the Civil War, where Michigan supported the Union and therefore buried from a different avenue the challenge to their existence and in reality White domination.

But Detroit did not play any useful roles in Michigan until the reconstruction era, and with a matter of decades following their entrance to the United States, there were efforts towards uniting the Erie River to the North of the United States and to the Union. With the beginning of Erie Canal in New York, early efforts were made to connect the River Erie of Detroit to Erie Canal, and under the Silhouette of Samuel Chase of Michigan, the railroads connecting Detroit to Chicago and from Chicago the rail tract runs into New York. The First World War brought greatest migration to the area, initially dependent on food crops such as rubber plantations used for various things and ships through the main tracks to the North, led to the coming of Rise of big companies that experimented elsewhere but found their home in the Riverine Jefferson Boulevard, all of which was compared to match the maps of Washington D.C and parts of Virginia, and the author of this idea was a man among the five appointed by President Jefferson to help widen the base of Detroit.