Not for Charity - not for Sale
By
Sampson Onwuka
The Chapter was destined to be written and the final solution begins from where we started….
There is something about the Medical Institutions and the Act of medical discoveries that can plunge an entire world of information into some abyss until perhaps redemption. All the breakthroughs in science and technology need not be rehearsed as a consequence of these long years of experiment and studies, leading to disasters of all types and sometimes with some degree of consequence. One man whose theory concerning the problems of perpetual error and why institutions carry on with these mistakes is Joseph Greenberg in his dissertations about language and human dispersion theory, theories well evident by the Luigi Cavalli-Sforza. Mistakes can be conceived by any number of institutions and can be transferred from one form to another and until a breakthrough; it survives some of the assumptions in business and elsewhere. The advent of HIV at least in the least in the last 35 years is no different from this kind of problem, especially those of Polio which has given us all the headache known to us.
That a thing and perhaps a sickness such as paralyses from Polio eluded the frontiers of sciences for at least 40 years in spite of the breakthrough by the Karl Landsteiner on A, B, O on the bone marrow and the brilliance of a certain Jewish immigrant by name Simon Flexner who for his sake and for the need of medical research that they developed the Rockefeller Institute in New York.
These men including those took umbrage under his leadership, (1) Herald Cox (2) Max Theiler (3) Isabel Morgan (4) Thomas Francis (5) Tom Rivers (6) Peter Olitsky (7) Albert Sabin, names very familiar with us in Virology and the culture, and like in many open sources these are champions of medicine for many years in vaccination and early attempts stem cell research. The book that throws some light on the history of these few including the familiar Max Theiler who succeeded in growing a Virus in the brain of mouse is called Polio; An American Story, by David M. Oshinsky (05), we should be able to quote from this book, at least in gainsaying on some of the assumptions about the connection between Polio and HIV, where the author made some medical blunders no more than the ones that Merck made about the unknown dynamics of the human immune system.
But in Oshinky’s ‘Polio’ story we are privy to his citations describing an important figure in fight of Polio by name Karl Landsteiner that “At his Laboratory in Vienna, Landsteiner produced an emulsion from the Spinal cord of a boy who just died of Polio. He passed the liquid through a porcelain filter, injected the contents into the stomach of two rhesus monkeys, and waited to observe the result. It didn’t take long; the monkeys proved to be wonderfully susceptible hosts. Both succumbed to Polio, their spinal cords showing much the same damage that had occurred in the little boy.
The Polio virus had been isolated.” The process of extracting a virus would in future be that complicated but they follow the same process, yet the intentions behind rendering the piece in spite of the Polio is taint the discourse with the bone marrow incident regarding the treatment of immune deficiency syndrome that much effort has been put in to help the victims of the AIDS whose bodies are racked by the virus by chemotherapy in removing much of the bloods in the spleen and bone marrow of the affected areas or areas of interest, and using a foreign entity and bone marrow try to restore the blood of the patient in a process that is similar to cancer treatment yet they get worse and worse.
The point that HIV is at least for now a blood borne Virus does not.....
If the virus is fed through the mouth the victim hardly suffers any special injuries and any specific inductive injuries but when the Virus is fed through the nose, the reactions were very fatal. In fact the mode of infection which are so believed as the same and similar to Tuberculosis which infected people through the nose and breathing, cursed severe reaction in the body of the victims particularly the monkeys, may have given some reason that the mode of penetration of the virus was similar to other agents of the body.
David Oshinsky writes that “No one found a way to block poliovirus from entering the body or to neutralize it with drugs or chemicals once it got inside” For many years the conception that the nose was how the virus entered the body proved frustrating to scientist and in the image of Simon Flexner who help to carry out major reforms in virology, there was hardly anyone to challenge the basic assumptions.
There was something else, apparently the reason why the mouth feeding of the virus did not convey any particular kind of adaptive meaning, is that the monkey used for these experiment is called Rhesus monkey. Its ability to mount immune response depended on many things, in part for the silaic acids which are contained in the body and are presence in the nose and nasal cavity, exfoliates its existence and as someone theorized, many people did not know why we couldn’t stop the virus from entering the body. It would seem that it was only through the nose that such penetration of the body was possible.
The story on how it was discovered that other primates reacted differently to the virus when fed from the mouth is not clear, but the opposition of Flexner to the use of these primates proved that it was a well-known fact or suspected as such that a particularly kind of monkey acted differently when the virus is fed through the mouth. The rest were victims of the same thing. For that reason, the understanding that the route of the virus was from the alimentary canal and not the nose or at least more than nose, proved a damage to Flexner’s theories and became a point of rally for all scientist. This new knowledge is so critical to further enhance the experiment on Polio viruses that it led many scientists to shift their attention from monkeys to chimpanzees.
Oshinsky put it kindly that “if Polio virus entered through the mouth and worked its way down the digestive tract, then it must travel through the blood before entering the central nervous system. If so, a vaccine designed to raise anti-body levels in the bloodstream would be able to neutralize the virus before serious damage was done.”
From this development, they were able after almost forty years of the studies on Polio virus to now learn how the virus develops and what makes it work and why the virus became a hit for the rest of the scientific America. At least Scientists were now able to focus at (early infection) and the blood stream was the place. In the words of John Paul, “It meant that small amount of virus which invaded the blood could probably be overcome by relatively small amounts of circulating anti-body, and by this means could be blocked from gaining access to the central nervous system….At one fell swoop, the problem of immunizing man had been rendered easier than was expected.”
Among the first investigators to look at the virus in previous and neglected blood samples was a certain Dorothy Horstmann, who was a member of Yale crack Polio Unit team of invested much of her time in looking at blood of the victims that came into the hospital from the 1943. A basic line should include David Bodian and his group; she was not the first or the only one that looked at the blood of the victims that were infected by the Polio virus. And the blood became very central to the point of demonstrating from the stored blood of nine year old, that unless the virus was not in the system and in the body already, there was no way of knowing unless she got sick. That it was only on this account did any change take place in the body at all, that as soon the blood realized that it had a disruption in its system, proteins and folded inwards and then the attack on the nervous system which is primary to the virus.
If fed through the mouth the virus could invade all the stomach and reach down the body where it profligates, but majority of time and according to several practices which are done, the virus hardly makes it into the blood stream in large amount when induced through the mouth of some monkeys and ended up creating paralyses leaving antibodies which has neutralized the virus. The whooping size of his academics raised the tempo of suspicion towards Apes, Chimpanzees, and Monkeys as probable origins of the Virus which eventually came in with their mutations in human and hence nearly justified the all kinds of experiments in Congo.
I must confess I have only casually flip through the books and do not intend on writing on what clearly obvious from his missive that the general academic consensus favors a Spillover from Monkeys and Chimpanzee into Human beings.
Philip Alcabes (2010) Dread book that attempts to consider what the early CDC workers attempted to achieve with HIV and how some of the jokes about HIV did not shy from the social stigma of those who were called freaks or in the 60’s bums, who suffered all kinds of malfunction in the body and were essentially housed elsewhere till perhaps redemption which sometimes arrived too late. If it is not impossible to locate this item elsewhere is because of alternate historical account of outbreaks in City wide location, point to breakthroughs that gave medicine a new and profound meaning.
In his chronicle on HIV he pointed to an early date made by CDC released in September 1982, that “Homosexuals or bi-sexual makes – 75%, intravenous drug abuser with no history of homosexual activity – 13%, Haitians with neither a history of homosexuality or intravenous drug abuse – 6%, persons with hemophilia A with no other risk factors – 0.3%, and persons in none of the other groups – 5%.” Whereas anyone could get the virus he argues, HIV was simply the most dreaded thing partly for the fact that there was no cures at the time, but largely for the social stigma that was associated with it. Many of the Black and Hispanic in New York did not see it as very present and dangerous virus capable of infecting black as well others, and they loathed the virus as a white-man disease.
But before long, it was gradually shown that the virus began as a series of carefully planned conquest over the host immune system, and after a decade of the virus of the human it degenerates into something else.
For if Blacks were gradually gaining up to others despite being one of the smallest groups of minority in New York in terms of new cases on HIV, it was due to the problems of information and reaction, which do not add to anything useful.
For Asians and Africans, they were largely hung over on the transfer of the new virus emanating from Gay Communities in New York to other parts of New York and elsewhere, and since they loathed these communities; they are easily vulnerable to the viruses. Although New York in times past may have entertained the arrival of diseases and other infectious disorder, it has lead the fights against dangerous diseases, against Polio and Influenza, against diseases; both airborne and waterborne. The City is hive of visitors with long term view of the City and travelers for other reasons and immigrant population since the 18th hundred has continued to sprawl till very recent days.
New York downtown has no particular architectural, the immigrant populations; Irish, Italians, Jews, Africans, Caribbean, North and Central America, and other income capable brackets were primarily concerned with their own survival. Although the immigration continued in New York by Europeans, it helped to form some of the assumptions about new diseases and epidemics, to a point that it can be said that studies about the early diseases in New York in the last 100 years or so were mostly derived from reaction to outbreaks such as Chicken Pox (Varicella), Pertussis (Whooping Cough), Pneumococcus, Hepatitis A, Hepatitis B, Rotavirus, Influenza, Meningococcal and some variety of human papillomavirus. In a sense some of the assumptions about these diseases made outsiders temporary targets for reasons of their own.
The Polio virus was one of those outbreaks where a strain from African monkeys was very necessary in understanding the pathology of Polio which Flexner believed was generated from stomach to the body or through digestive tract – in essence it was ingested. Many of the experiments at the very beginning had to with mouth feeding of some of the creatures and primates – especially monkeys were fed through the mouth with strains of Polio virus and the end was not to the interest of the scientist. The main point is not the process of profligate Polio virus but on why it was necessary to ingest the various from the beginning and why the issue of blood pathogen proved a different and difficult point to redress. Look at it differently, when it became very clear that the Polio passed through several processes and especially the blood, the science committee was more than ready to handle the Polio mellitus once and for all.
Secondly, if the mentioned virus-ridden diseases and conditions, especially Influenza and Spanish Flu for instance of the 20th century A.D, were considered from purely medical and biological point of view, they show patterns of infection and host-DNA which alters the destruction of the infection process of the virus, some produce fever others with the same viral infection may give similar but different infection in the body. The immigration population who make it to New York where left to places such as Randall’s Island, New York, a place which as the repository for those dead or dying. Of course they naturally remain quarantined saving for instances of Polio and viral strain of its culture.
The modernity of New York as now and then appears on the world map and its visible schools of medicine was not always the case, for at least we can set our eyes on the formidable FDR days, whose efforts as Governor of New York and eventually president proved a watermark for the attitude of the public to issues of health. It would not mean that Harlem River drive heading the F.D.R was named after for political reasons, but the combating of Polio by forces affiliated with his office such Bob O’Connor makes the faithful date of CDC recent as they provide the necessary tools towards the growth in health we have seen over the years. But needs be mentioned that a lot list of all the breakthroughs of sciences in the United States and in the world did not arrive by idle conjecture, did not arrive by efforts of any one group such those for instance at Rockefeller Institute which has fielded and trained more competent and decisive virologist in the last formidable century, more than nearly all institutions anywhere in the world.
Perhaps the Pasteur Institute of Paris or other Schools of interest in Massachusetts; Harvard, etc., which though perform its function along the elite schools of the country, cannot in itself expel the contribution by other schools either directly or indirectly influenced by Rockefeller Institute in the last century.
This will not mean that schools such as City College of New York with as many Nobel Prize winners as Yale is to be taken away, it shows however that the merit of open culture and attitude to this merit widens on the even the smallest avenue of possibility that what works in one area, may not apply in other cases. It will be useful to point that the Cold Spring Laboratories in Long Island maintained an open culture and relevancy of attitude to science from the days of its founding by Watson and Company to nearly all combating of new virus which CDC is particularly known for. That will add to the assumptions that the failures over the years to deliver on HIV may be due to the fact that it was believed to be disseminated through deviant sexuality and the encouraging the scorn that it was created by God. But if half of what learnt over the years and at least in the opening heroic search for cure at the beginning was never replaced or transferred from one community to another, we may have in my view – purely in my view – put a final end to the Virus.
While it is easy for me to accept that giant steps in Medicine has failed in generating final solutions for HIV, it serves then as well now as an example for what may have transpired between Polio Virus and the arrival of the scientist who ended the whole sage. In areas I succeeded might clearly interest you with the fact that I spent 2 years studying Harvard Medicine for fun of it. And in the last returning decade and a half have spent hours of a given day on History, Anthropology, and generally studies human genetics. Majority of these studies show it’s relativity to HIV and the cure for immune deficiency syndrome prove a lengthy stay for reasons of their own, to a point that some of the conclusion vary in its results and the end point was a question of some understanding about viruses and its evolution. This aspect of our understanding of biology and chemistry is very important given the very reason why vaccinations seem to have failed.
Barely a year ago, the argument about the SVO40 virus supposedly from Chimpanzee and the Polio virus seem to have stagnated between Chimpanzees and human immunogenic viruses, which may have resulted the strain from Polio considered a leading item to HIV. But this argument in all its forms had to be dealt with, perhaps decisively given the basic premise of HIV infections and its pathology. Put it differently, there is no connection between Polio Viruses and HIV, and there is no link between immunogenic viruses which infect primates and humans saving the issues of the patterns of infection and the chief cause of the agents. The example about the slow viruses and oncogenic viruses are especially important largely for leading but misleading line of reason about HIV and the very knowledge of viruses and immune deficiency syndrome.
Looking backwards to some of the stories from Bronx and from parts of White Plains, New York in the early 90’s, there is hardly anyone who knows what the virus was all about and what its problems anywhere. It was known to be deadly, known to remain dormant for a long time, to be conversant with Homosexuals and with illicit drug users, where they speculated that sharing needles was very dangerous because of the dangers of blood contamination. Special classes are taken to handle blood and the secrets keep so tightly about victims that even some of the workers were placed on a need to basis. On a special basis as well, there are reference to Russia and the events of Cold viruses, including period of long epizootic and Moritz Kaposi (Russia) associated with description of what eventually considered Sarcoma, and pox related virus sickness.
We have reached perhaps another threshold in the studies of Biology and we are looking at the period in Medicine when the theory of the Human Immune Deficiency Syndrome can be finally given an official obituary. In keeping to themes of 2014 August 12th, and the injunctions justifying great periods in the annals of world history, we can begin from May 15, 2015, to attempt a public analyses of the theories involving HIV and how it can finally be set aside for all times. It may not be the case when there are various cases on HIV stories that need not be repeated but do generate as much enthusiasm as new breakthroughs in Biology. Drawn from the piece from last year, we can recall that the emphasis on Polio Virus was the author’s systematic strategy in analyzing some of the gaps and deficiencies which bar the final solutions and answer for Interleukin-2 virus and HIV. To the extent that this author classified HIV as a blood cancer was no new article of faith, it was driven perhaps by lateral arguments on Lentivirus and the slow Visna viruses some of which are gradually due to the origins of the strains. One of the flim-flam from Robert Gallo is the attempt at correlating Cancer or Oncogenic viruses and HIV, that is Oncogenic and Lentiviruses such Visna develop gradually inside the cell of the recipient.
In a forward by Bill Clinton to the book written by - San Francisco, November 26, 2012 - to a new book on HIV/AIDS anthology, he asked the same questioned we have maintained over the years, “ that when the history of HIV/AIDS is at last written, what will the final chapter look like?” And former Secretary of State Hilary Clinton maintained that “…the goal of an AIDS-free generation may be ambitious, but it is possible with the knowledge and interventions we have right now. And that is something we’ve never been able to say without qualification before. Imagine what the world will look like when we succeed.”
Visionaries write the Final Chapter One AIDS – The First
In an essay on a new book by Neil Giuliano presented by Andrew Hattori on the issue of AIDS in a new and recent book, that when the final chapter on AIDS is written, what will it look like? This provocative question is posed to 15 authors—political leaders, researchers, activists, and pioneers—in How AIDS Ends, a special anthology produced by San Francisco AIDS Foundation featuring a foreword from President Bill Clinton.
“Each contributor to this anthology has been deeply touched by AIDS and each of them, including myself, is equally committed to realizing that joyful day when AIDS is part of our past, not our future,” said Neil Giuliano, CEO of San Francisco AIDS Foundation. “How AIDS Ends captures this forward-thinking spirit and reminds us that when it comes to the fight against HIV/AIDS, there is no shortage of hope.”
Contributors include Timothy Brown, Jeanne White Ginder, Cleve Jones, Barbara Lee, Mark Dybul, Paul Farmer, Robert Gallo, Mervyn Silverman, Diane Havlir, Scott Wiener, LZ Granderson, Hank Plante, Eduardo Xol, and Neil Giuliano. They share their unique perspectives on the HIV/AIDS epidemic, their visions for how it ends, and who they will remember when that day comes.
“When we finally defeat this disease—hallelujah!,” writes Jeanne White Ginder. “I think on that day, I will feel that Ryan did not die in vain.”
“Now is the time to write a new chapter in the triumph of hope over despair and love over fear and hate—a new tale of the wonder of the human spirit,” writes Mark Dybul, the newly appointed executive director of the Global Fund to Fight AIDS, Tuberculosis and Malaria.
“When the AIDS epidemic ends—when we have a vaccine to prevent new infections, and everyone who has HIV can manage it with drug therapy—what a joy, what a relief,” writes Dr. Robert Gallo, one of the co-discoverers of HIV. How AIDS Ends is published as a digital book and is available through Amazon and other online retailers for 99 cents. All proceeds from the book will be used to support the free HIV prevention and care services of San Francisco AIDS Foundation that improve the health of thousands of people every year.
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Some of the assumption can be reduced to the schools of interest that make a difference between and
Dogma for HIV
It is translated from one person to another through blood and sexual contact showing signs of Rash, Kaposi virus – Michael Gottlieb,
It does not transfer from one primate to another – Sampson Onwuka
It is a lentivirus – it kills slowly and separate itself from Oncogenic viruses because of the Interleukin 2 – Luc Montaigne
It is an oncogenic virus and show patterns conceivable close to a strain of cancer which seem parallel to a strain of monkey virus from Zaire - Robert Gallo
It is a blood Cancer comparable to the – Sampson Onwuka
It refrains from DNA of the host and does not have personal DNA and it has two pieces of RNA – CD4 and Retro-virus – David Baltimore
It is Thymus depended – a general dogma and has a tendency to use E. Coli and Streptococcus
Its formative origins may have started differently – perhaps male to male – primary productive isolation – Sampson Onwuka
Vaccination is Contagious – and probably unsafe – Prophage and Age of Bacteria – Sampson Onwuka
People do not necessarily die from HIV, they die from opportunistic infection – general dogma
HIV virus is not the only immune deficiency syndrome, auto-immune failures can be induced by drugs and
Use of AZT and other drugs may be useful in decreasing the Course of the Virus and not the rest…
Put it clearly, we must necessary understand that the process and complication of thymus as a sugar complex ; the CD4, the penetration of the human immune system by locally manufactured foreign virus (HIV) and the gradual evolution of a prophage whose life retains a DNA from previous reproductive process gives us the impression of Immune Deficiency that is determined by the ability of existing DNA and genetic substance – Cytosine, Guanine, Adenine and Thymine, and here we can easily lift from Genetics Home Reference the following definition, that “DNA bases pair up with each other, A with T and C with G, to form units called base pairs. Each base is also attached to a sugar molecule and a phosphate molecule. Together, a base, sugar, and phosphate are called a nucleotide.”
So together, a base, sugar, and phosphate define nucleotide, and from well-rehearsed arguments from last year, the finally parted ways role of Thymus is rebuilding human DNA, that the complex breakdown and regeneration of life was considered a well distributed responsibility among the primary chemicals but like Bromide-5-Methylation, the process of adapting the body to new realities is something achieved by Thymus or CD4s. The author also identified the particular kind of sugar dissolving bacteria that can considered – part and central to these process – especially the introduction Avery Oswald, Alfred and Martha Chase well received experiment, perhaps with reason and succinctly by French scientist Andrew Lwdolf, Jacque Monod and Maurice Francoise, especially Jacque Monod and the emphasis on E.Coli.
If suggest that the title of this essay and in fact one of the more important essays of our generation should be 'Kicking the Ass of AIDS' but we shall open up on this topic by citing that Human beings have always found themselves challenged by all plaques since the beginning of time, that the great advantage of our time is the new techniques and new machines are being used, and are to investigate on this virus and are sometime successful in discovering of the agents responsible for these new virus and infection.
The title of this essay and in fact one of the more important essays of our generation should be 'Kicking the Ass of AIDS' but we shall open up on this topic by citing that Human beings have always found themselves challenged by all plaques and have always had the sciences to defeat them but as victim of our personal institutions and unyielding institutions in understanding the errors associated with long held Theories, some of these plaques and diseases or infection such as HIV tend give more headache that its needed and then the cure is usually decades away instead on a few years. I shall mention that going forward; the cure for HIV/AIDS can be reduced to a few years.
I should be childish to indicate that based on half my knowledge on the subject, I can master and kick the ass of this virus in months of uninterrupted lab work. Some may at the sheer optimism of someone without a doctorate in Medicine or Biology. While it is easy for me to accept that these giants in Medicine failed in areas I succeeded, I might clearly interest you with the fact that I spent 2 years studying Harvard Medicine for fun of it. And in the last returning decade and half have spent hours of a given day on History, Anthropology, and generally studies human genetics. Looking backwards to some of the stories from Bronx and from parts of White Plains, New York in the early 90’s, there is hardly anyone who knows what the virus was all about and what its problem anywhere.
It was known to be deadly, known to remain dormant for a long time, to be conversant with Homosexuals and with illicit drug users, where they speculated that sharing needles was very dangerous because of the dangers of blood contamination. Special classes are taken to handle blood and there was secret keep so tightly about victims that even some of the workers were placed on a need to basis. One of the books that recollect some of the stories in the Bronx and New York, is the book by Philip Alcabes (2010) Dread, considering the what the early CDC workers attempted to achieve with HIV and how some of the jokes about HIV did not shy from the social stigma of those who were called freaks or in the 60’s bums, who suffered all kinds of malfunction in the body and were essentially housed elsewhere.
In his chronicle on HIV he pointed to an early date made by CDC released in September 1982, that “Homosexuals or bi-sexual makes – 75%, intravenous drug abuser with no history of homosexual activity – 13%, Haitians with neither a history of homosexuality or intravenous drug abuse – 6%, persons with hemophilia A with no other risk factors – 0.3%, and persons in none of the other groups – 5%.” Whereas anyone could get the virus he argues, it was simply the most dreaded thing partly for the fact that there was no cures at the time, but largely for the social stigma that was associated with it. Many of the Black and Hispanic in New York did not seem it a very present and dangerous virus capable of infecting black as well they loathed the virus as a white-man diseases who like in the ass.
But before long, it was gradually shown that the virus began a series of carefully planned conquest and after a decade on the virus, it Blacks were gradually gaining up to others despite being one of the smallest groups of minority in New York. For Asians and African, they were largely hung over on the transamination of the viruses through Gay Communities in New York, since they loathed these communities; they are easily vulnerable to the viruses. Although New York in times past may have entertained the arrival of diseases and other infectious disorder, it is has lead the fights against dangerous diseases, against Polio and Influenza, against diseases; both airborne and waterborne which some travelers and immigrants brought to New York, in which several places such as Randall’s Island, New York, served as the repository for those dead or dying, remain the quarantine when there is instances of such cold and influenza in all classes of respect and decorum.
The modernity of New York as now and then appears on the world map and its visible schools of medicine where not always the case, for at least we can set our eyes on the formidable FDR days, whose efforts as Governor of New York and eventually president proved a watermark for the attitude of the public to issues of health. It would not mean that the anointing of Harlem River drive heading the F.D.R was named after for political reasons, but the combating of Polio by forces affiliated with his office such Bob O’Connor makes the faithful date of CDC recent as they provide the necessary tools towards the growth in health we have seen over the years. But needs be mentioned that a lot list of all the breakthroughs of sciences in the United States and in the world did not arrive by idle conjecture, did not arrive by efforts of any one group such those for instance at Rockefeller Institute which has fielded and trained more competent and decisive virologist in the last formidable century, more than nearly all institutions anywhere in the world.
Perhaps the Pasteur Institute of Paris or other Schools of interest in Massachusetts; Harvard, etc, which though perform its function along the elite schools of the country, cannot in itself expel the contribution by other schools either directly or indirectly influenced by Rockefeller Institute in the last century. This will not mean that schools such as City College of New York with as many Nobel Prize winners as Yale is to be taken away, it shows however that the merit of open culture and attitude to this merit widens on the even the smallest avenue of possibility that what works in one area, may not apply in other cases. I
t will be useful to point that the Cold Spring Laboratories in Long Island maintained an open culture and relevancy of attitude to science from the days of its founding by Watson and Company to nearly all combating of new virus which CDC is particularly known for. That will add to the assumptions that the failures over the years to deliver on HIV may have been due to the fact that it was disseminated through the stigma of deviant sexuality encouraging the scorn that it was created by God. But if half of what learnt over the years and at least in the opening heroic search for cure at the beginning was never replaced or transferred from one community to another, we may have in my view – purely in my view – put a final end to the Virus. The Chapter was destined to written and the final solution begins from where we started….
One of the things I was privy to is the suicidal behavior and tendency of the victims leading me to understand why in the end, preventing the expansion of HIV was both dependent on the conscious decisions of the diagnosed and the attention given to the lifestyle on those either not sure or those with redoubtable status. The later may account for obvious cases of HIV transmission some of whom understand the implication of their lifestyles but would rather play ignorant to a HIV than face the emotional injury and social stigma associated with recently diagnosed. It is not enough to claim that a socials stigma for HIV is not as strong as may have been suggested, it is however a state of mind that welcomes the cure is not yet available that leads to doomsday psychology. Majority of the emphasis on this virus and patient is created in such a way as to suggest that it is the sexual activity of some group of Americans, for instance the so called Gay or Lesbian (?) or the African Americans whose nature is prone early healthy sexual life, are those who are major players in the spread of the Virus.
The other such as the Latino and Hispanic community has also noticed a spike in the new cases, largely for the attempt at testing for the Virus than other means. But in the end, the last two groups receive the highest blame for the spread of HIV, whereas, anybody can infect others or infected by others. These stereotypes, particularly the problems of expertise of the field, Doctors or Nurses or Health Care experts, loathe observations by nearly anyone without a badge of certificate or honor. As such only those who caught the Virus and those with close family member with the diagnosed status that are interested in the learning about HIV with a degree of interest. The rest of us are incurable expat on opinions and diagnostic made available by those in field, but by condition of more direct investigation of the Patients and their drugs, we are able to see through the understandable but proud-ridden closed-off of medical institutions; CDC (Center for Disease Control) and private medically experts each seeking in their own ways to find the cure for HIV – one of the Viruses that can lead to Immune Deficiency. The reasons why these organizations react with disdain to such things are many, including a possibility of Abuse and use of a medical terms that need explicating to novices, but it seems that the terms and conditions are no replacement for the Virus itself and why more can be done towards a better understanding of the Virus, why it attacks or attaches itself to a CD4 host and why in the end, the Virus overpowers the immune system.
The few stories which we remember from the early years of the virus includes one concerning the Kaposi Sacoma which appear in the skin of mostly HIV position homosexual male. The Candidiasis appears in blood groups of mostly Hemophiliac and people with chronic cases of blood thinning and Pneumonia. The transfer of blood played so significant and blood management also played a serious hand in deciding early reaction to HIV and from downtown New York was a man by Michael Rosenberg who dies in 1994 from blood and HIV complications not before founding the Hemophilia/HIV peer Association, which sort at least in New York to monitor blood distribution and donation through the State.
AN outbreak of contaminated Blood plasma in Tokyo a decade earlier threw a lot of light of how the confusion between Hemophiliacs, Sickle Cell, and Blood Anemic patient peered off with cases of compromised immunity sped through blood donation and government officials and how they affected people with HIV in New York and many other parts of the country. Whereas the issue of blood transfusion and Plasma donation has been partly common in New York due to a peculiar kind of immigrant entering through its harbor, it never amounted to grave and deciding consequences until there were obvious problem of pox developing in the blood of victims of a supposed newly linked virus.
One of the earliest warnings on the blood transfusion came from Susie Quintana who was believed to have contracted AIDS through the process, but the litigations did not arrive on time for her settlement which eventually reached 8 million dollars. The other early warning on blood transfusion came through Corey Dubin who like many people in the 60’s, 70’s and 80’s in New York and Los Angeles receive blood transfusion as Hemophiliacs contracted the immune deficiency after receiving Factor VIII with ‘experimental clothing factor’ as a child, had struggled with his immunity and had reasons to believe that the poor regulation of the Internal Society of Blood Transfusion and the use of gamma globulin in restraining Hepatitis considered harmless by scientist.
These stroke of different shades provide insights into the history of blood pathology and the effective means to fight them which may or may not have provided the background to the studies in Pneumonia, but most perhaps prepared to the landing of the Gallo team based in new York, who successfully isolated the virus for Leukemia and what they collectively call Retrovidirae, beginning with HLTV virus group that oncogenic but has not linked to any particular form of cancer beside the blood associated pneumonia.
Robert Gallo team did find it compellingly to relapse into the studies on the latest vaccine used at the height of Polio, to the point that some of the conclusion regarding the deep Cameroun boundaries and the Congo where the HIV is mainly to be located seem to have started with his clearing on this topic. The corrections are long since observed that other parts of world has presence of what seem to be similar to HIV, but the foundation explicating of why it was Africa or any region in the world has not really surfaced among scientist. It is tradition that several diseases not familiar with man is perhaps deeply in severe locations of the world, as such the moving from these creatures to human could have resulted from recent contacts and may have triggered dormant bacteria or viruses which cause 75% (three quarters) of the Cold virus in human beings, much of with simply lay dormant only on compromised immunity essentially take over the body.
The discoveries of the French team lead by Montagnier are no more than what they are, exception based on the virus that used as a prototype, to the point that a connection to the earlier years of those whose Kaposi Sacoma in New York could not be treated and who deficient in the defense network, points to deviant sexual behaviors, to some point separated from those in Los Angeles, who though had the same virus evident in their body, where also showing some depression in the system and the presence of candidiasis including breathing problems. It is therefore not an immaculate conception that the breakdown in the body of those diagnosed with Pneumocystis – itself a fungus with some of its element are copious bacteria without walls usually classified as Mycobacteria loosely for they do in epigenetic methyl based complexes, than the cold they could create, perform the same havoc when tripped like staphylococcus and streptococcus which perform separate disorder in the body but primarily infection leads to cold, either in the first primary phase or when contracted through a secondary agent.
The imperial weight of the changing dynamics of the human cold driven viruses and bacteria is why there is new need for vaccination against influenza every year. The cold with its new pollen dust simply trips the dormant and friendly viruses in the body leading to dysfunction of the type I and II alpha globulin defense system in names of mucous and in the names of microfibers in the intestines where lymphocytes depressed histones mount a first attack – albeit sneezing or allergic reaction.
Irwin Sherman (2007) we cite that “HIV has in its genetic blueprint 10, 000, nucleic acid bases (adenine, uridine, cytosine, and guanine, or A, U, C, and G); That is about 1/100, 000, the number of nucleic acid bases we have in our each of our cells. The genes of HIV consist of a long string or strand of nucleic acid bases built into this strand, in a coded form, is all the information needed for the manufacture of its proteins. Each gene has a particular sequence of bases in the RNA. The genetic code is a triplet codes that is, three nucleic acid bases (called a triplet) code for one amino acid.” This important for similar reasons that a Peter Deusberg’s on HIV assessment considered, that for him, Deusberg ignored the fact spread of HIV could occur through regional lymph nodes.
Whereas certain others who tried a life-form of polio vaccination may be accused on genetically and inadvertently triggering a new Virus altogether are not that not guilty, they, like the those who used a dead virus are innocent in spite of the acceptance that a certain SIV 40 strain of monkeys and perhaps Chimpanzees were found in the vaccine that this like even S1V and SV1 or SIV2 does not affect human beings or make them sick. The primary challenges of Peter Deusberg to Luc Montagnier and Robert Gallo is that the virus called HIV could not have been new, may have an original virus existing in the human body or familiar with human body till the social habits of drugs particularly familiar with Homo-sexual began to take a hit on their immune system. The Arrest house of the lungs raised for Verghese points to this very fact that various diseases are kept under arrest by the body and y the actions of the Chromosome 8 until the defense system is broken to the point that the body can no longer synthesis, split and condition these viruses.
The Cold Viruses like the Bacteria in certain regular circumstances is likely a breeding gamut for cold environment and unlike Bacteria who explode in more hot climate and moist environment and which can also die when extensive exposed to heat, we find that the creatures that are mainly associated with these viruses are usefully discovered in these areas. One of these cold bearing viruses common in Russia and further up is the water fowls. One of the greatest associations of the water fowls to cold is the arrival of epidemic such as zoonosis like we find in Russia, where a certain form of death occurs rapidly among the water creatures such as fowls, and like we find in other places with enormous categories of dead fowls, a shift in environmental conditions may give some indications of a peculiar arrival of a any new form of Cold Virus such as the Avian for instance.
We may have noticed that the rest of the general physiology of the body as we observe in nature is to be interpreted as the product of what lies within the body. That we have arrived from the history of the older times to the age of enlightenment with various understanding on how the body works and why it differs from one to another, that it inherits certain diseases from the host (parents) during the meiotic, that the system in of itself can be damaged and can lead temporary and permanent injuries in the body. The body in of itself can regulate itself, thrives on its self- sufficiency (Claude Bernard), that the Microbes described in ancient books could be seen on microscope (Leuwenhoek), that they harm the body and could not be called one form (Henle), that these could also be studied and separated according to the disease they create and the infection in the body (Koch), that these viruses are old and region specialized (Darwin, Mendel), there is a Germ plasma (Pasteur), there is a mortal soma (Weismann), that these two must repeat in such a way that the rate of reproduction could be matched by the body, can be achieved through the mastering the Germ and the Plasma leading to the products of proto-type such as Penicillin (Jennings).
There other foundations of Biology and medicine that are important, used in part by Peter Deusberg that viruses capable of causing epidemic should be new viruses – set in order of Koch – where the theory was also placed in different in terms of (Farr) on the veracity of a New Virus. While we may indicate that the whole statement raised by these experts are true, they are true to the extent that the body could easily adjust to changes in the body and in the environment if and when the exposure to the system do no prove fatal. It is taken that these viruses capable of destroying the body in slow or speed motive are doing so for many reasons including that the body and CD4 cannot keep up.
However there is no going that HIV is an infectious disease in keeping to Deusberg and in Order of Farrs - HIV viruses do not meet the criteria for infection, adding that the virus is considered a retrovirus essentially to the careers of Gallo, Baltimore, and Montaigne, whereas retrovirus and the reverse transcription of RNA to DNA and DNA to RNA through an enzyme, means that HIV could have been the reasons for AIDS as according to Deusberg, but in all, shows that the total damage that the body can sustain is sufficient to satisfy its healing and its cure so long the exposure does not directly and indirectly kill the system composed mainly of active cells. For that, there are chances that the bi-product of the human body which are physical and which separate us from each other, can traces of the returning few months and carry viruses and bacteria that the body pushing out.
In practice, the total amount viruses and diseases that can exist the body or at least circulating within a given community may be considered relatively comparative to the amount of human activity in this period, may remain within the comparative ration until unusual activity such as industrial expansion or disease bearing animals not familiar with an environment and ecosystem interferes, then there is event horizon.
From the levels of the DNA philosophy and the ordering knowledge of the Sciences available to us today, there is no question that it is a mistake to view without reason or even without books, that a certain virus could possibly exist somewhere in the Universe that do not have the basic DNA familiar to mammals, that do not have a basic structure that can understood and tampered, and can be used in experimental isolation of several key minerals in the body or in the body of the animals which they came from.
For instance, a Histone and Histamines are minerals based Enzymes that can be extracted from Birds and Calf as well. Histones are found in the Calf Thymus and in Spleen and Liver of bovine mammals, but in all, they can also be found in the Spermatozoa of these Bovine creatures. Between the Thymus of Calf and its Spermatozoa is one product that are found the in the mucosa intestine, will not propelled a connection between Thymus and Spermatozoa, ready-make the answer the secret of mammalian existence in the final product or Spermatozoa.
Vaccination…
We may have noticed that the rest of the general physiology of the body as we observe in nature is to be interpreted as the product of what lies within the body. That we have arrived from the history of the older times to the age of enlightenment with various understanding on how the body works and why it differs from one to another, that it inherits certain diseases from the host (parents) during the meiotic, that the system in of itself can be damaged and can lead temporary and permanent injuries in the body.
The body in of itself can regulate itself, thrives on its self- sufficiency (Claude Bernard), that the Microbes described in ancient books could be seen on microscope (Leuwenhoek), that they harm the body and could not be called one form (Henle), that these could also be studied and separated according to the disease they create and the infection in the body (Koch), that these viruses are old and region specialized (Darwin, Mendel), there is a Germ plasma (Pasteur), there is a mortal soma (Weismann), that these two must repeat in such a way that the rate of reproduction could be matched by the body, can be achieved through the mastering the Germ and the Plasma leading to the products of proto-type such as Penicillin (Fleming).
Alexander Fleming after his long explicating on the limiting factor of bacteria at the perhaps phage level, invented penicillin as a ‘limiting factor’ for staphylococcus, or as they coined, ‘growth inhibition effect of penicillin on Staphylococcus’. Fleming was associated with what is now called the Antibiotics which has set precedence in the light of many discoveries since 1929. In Germany in 1932 discovered that a lumen based ‘Prontosil is effective against Streptococcus infections’ which though not necessarily linked at a time to measles (proved a difficult treatment in Europe. It is this well tout idea of limiting growth or the profligate of Bacteria, either artificially or naturally as in the case between Candidiasis and Streptococcus Pneumonia, that in relative construct of the balance of some of the assumption in the body, there is a shift from seem like Dormant genetic of acquired Chromosomal inheritance and the bacteria that lies beneath it.
We may point to this import and decisive years in the medicine as instrumental in understanding how bacteria work, especially a phage level, to a point that a mass production of Penicillin in United States by Howard Florey was successfully established in the United States…..It needs be mentioned for historical reasons that the impact of isolating these limiting growth factors, inspired the works of later medical experts including Alfred Hershey and Delbruck, all of whom may be considered right in the light of some of the exercising impact of bacteria or viruses induced diseases or conditions such as those of Hemoglobin.
Wendell Stanley isolated the virus that causes tobacco mosaic diseases, which was completely shown to be Fungus family that also perpetuates its existence.
Gradually the number grow in the interest of those looking to isolate from the pact, that in 1948 Selman Waksman in the United States was the first to ‘isolate streptomycin from Streptomyces griseus’ which also provided that a means of inoculation and vaccine and eventually the advent of Poliomyelitis during the World War I and World War II, that makes its clear, that the greatest difficulty that the account of Salk and Sabin over the invention of Polio vaccine had to be settled outside academic exercises. For if we are to compare some of the changes that has taken place…..On account of Jonas Salk and the backing from supporter such as Basil O’Connor and following the breakthroughs in understanding the DNA and the double helix after two of the greatest scientist of the last century, James Watson and Francis Crick, then came other invention after Enders’ theory, that Albert Sabin opposed and put to be the dividing line for the age of the discoveries. Ender’s theories are a full re-interpretation of the accounts of the effects of the…..
Reading from the Verghese book, (1994), we discover the strange reasons why there is a failure in tying some of the loose ends of the study of the Virus. He mentions for instance that “…pneumocystis had a long history before AIDS made it a household word. Epidemics of Pneumocystis swept through Europe in the 1940’s. They occurred primarily in premature infants in orphanages, in the setting of overcrowding and malnutrition.” The author discussing this statement made overt connection between the depletion of one’s defense system and the activity of some external agent. That not all immune deficiencies are caused by Pneumocystis, that however Europe after the wars, discovered itself confounded by the cases of ‘immune compromising conditions’ and one of such was this virus and the other was also Leukemia which required long list of blood donors.
The author goes on to raise the question on the nature of the Virus and why as late at the 1990’s its pathology still eluded the most accomplished medical scientist. He asked “how are we to view this organism? As an invader from outside or an as opportunist from within?,” and he attempted to answer the question by reference a case of infecting a rat with pneumocystis pneumonia, that ‘all you to do is give the rat cortisone, - a potent suppressor of immune system – and the rate then spontaneously develops pneumocystis infection.’ That in comparison to the injections on the rate with Staphylococci, the rat is able to mount immune response. His conclusion and the conclusion of his colleague named ‘Betty’ from the Rat experiment is that “…Pneumocystis is present in low numbers in the lung at all times….The constant vigilance of the immune system keeps it in check. Immune suppression by steroids…AIDS results in unchecked multiplication of this organism.”
While the theories of the presence of pneumocystis (that is if and when contracted) in the lungs usually reverts to create pneumonia may be true to a certain degree, it is perhaps composed without respect to other experiments performed by medical doctors, that one, linked the presence of SIV from primates to humans, that both of the conclusion from Verghese and the general theory concerning suppressed Pneumonia virus in the body, fails to have incorporated the more basic science that the SIV linked to Polio Virus were not always found in the lungs of the primate. Would not mean that the lungs are safety houses for arrested viruses, would probably compel the secondary argument that the reversal of some virus conditioned by the actions of Chromosome 8, which is RNA Chromosomes houses or control about 95 percent of human genes which the body does not really need.
Simply put, the relationship between the Chromosome 8 and the functions of the human immune system is so well linked that it is possible to suggest that the immune deficiency which may result from any number of causality is within the limits of the functions of Amino Acids, particularly Cytosine, Adenine, Guanine and Thymine, whose structure is not variously changeable, but adapts to the presence of foreign elements by replacing either of major Acids in its Nitrogenous bases.
For if we take Verghese argument seriously that shortfalls in immune system can revert the problems of control to access the body leading to a damage of information systems as in this case Pneumonia from Pneumocystis, we push the argument that nearly all viruses arrested or conditioned for the benefit of the body may become by occlusion, very dangerous variously or bacteria as the case would be. In this clear that a perpetual breakdown of human immune defense may lead all kinds of conditions, but to the degree that a virus – either manufactured by the other and from a primary agent – would permanently weaken the body, suggest sometime systemic, and more that buries the special status or privilege of Pneumocystis.
Here we consider the point Verghese made about the presence of the virus in Europe in the 1940’s and try to explicate the departure from the various histories associated with such a virus to a reason that it started from Africa, by indicating that the formal intent of many medical students at the early stages of the virus was not to discover the cure but perform to discover what could cure the virus. In the opening accounts of the doctor’s books, he mentions for instance that he “…had arrived in America as a rookie doctor in 1980. At about the same time, HIV, the virus that causes AIDS landed in the port cities of United States; New York, San Francisco and Los Angeles.” The Virus, he said, “…arrived from Africa (perhaps via Haiti) carried in the bloodstream of one or more unsuspecting people who had then passed it on by sharing needles or through sexual intercourse.” The particular summary is quite difficult to conceive of, especially from the elemental view of an interest possessed with the origins of a named virus Pneumocystis which from his reading existed in Europe.
The conundrum from that statement is of epic proportion for at least it harbors the good and damn right bad about the veracity of HIV. If it is said to have been discovered very early as a marked by Pneumocystis which the earlier cases in Los Angeles cited and in conjunction with instances of Sarcoma in some already known Gay Couples in New York, his statement proclaims with the depths of ignorance involved in scientific quest for a cold virus, or it mirrors the prison in which the medical scientist and their institutional errors were by concerns or early theories which was rooted in smallest of experiments at Ely Lilly were laid to draw a misleading complex about the Virus. That a transfer from Africa shield as wells manes the resources available in Science in 80’s for making advances that left much of the world forlornly.
The danger of blood borne hepatitis and “plasma mills” as described in detailed by J. Garrot Allen. The other early warning on blood transfusion came through Corey Dubin who like many people in the 60’s, 70’s and 80’s in New York and Los Angeles receive blood transfusion as Hemophiliacs contracted the immune deficiency after receiving Factor VIII with ‘experimental clothing factor’ as a child, had struggled with his immunity and had reasons to believe that the poor regulation of the Internal Society of Blood Transfusion and the use of gamma globulin in restraining Hepatitis considered harmless by scientist.
These stroke of different shades provide insights into the history of blood pathology and the effective means to fight them which may or may not have provided the background to the studies in Pneumonia, but most perhaps prepared the landing for Gallo team based in New York, who successfully isolated the virus for Leukemia and what they now collectively call Retrovidirae. Beginning with HLTV virus group that oncogenic but has not linked to any particular form of cancer beside the blood associated pneumonia.
That for instance, “The lysogenic and non-lysogenic strains of Streptococcus pyogenes are far from harmless, since they are one of the two major causes of human infections and of pus formation in wounds. However, when lysogenic strains of S. pyogenes undergo virus-induced lysogenic conversion, they start to produce the toxin that causes scarlet fever….” That “After a few or a few thousand passages from generation to generation of lysogenic bacteria, the long-dormant lysogenic prophages suddenly revert to virulence and start acting like normal virus genomes. They take command of the chemical and metabolic systems of the bacteria cells. Inside of a few minutes, the cells start to produce hundreds of mature phage particles, enough to tear themselves apart.” This discovery was made the Fredrick Loeffer who worked on the Corynebacterium Diphtheria isolated by Edward Klebs and was considered a germ for diphtheria by Robert Koch, but was rejected or placed under suspicion by international medical community as bacteria that was not very destructive and was no less than what it was a common bacteria similar to streptococcus found in the throat…
But Loeffer eventually demonstrated that the bacteria isolated by Kleb was the agent that caused Diphtheria which did not have the toxin, however this bacteria was meant to remain dormant and friendly until its DNA structure was essentially altered by some other events in the body or in the circumstances relating to the human conditions. This adds to distemper the suggestion of Duesberg and the Laboratory experiment frequented but mentioned in this case by Abraham Verghese, that some bacteria can remain dormant for long time until triggered by the presence of Cortison or other drug that attached the CD4s in the human system.
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In this case, the point that “…increasing evidence points to hypersensitivity reactions of the immune system to antigens or the candida surfaces or the metabolic products of the organism…” will attract some new explicating since the latest ELISA test and the earliest ELISA test as based on the reactionary tendencies of the CD4. It does not mean that ability of any Fungus to evade the body relapses into the penetration of the body by the cell and the fungus, including its pathogenicity; how its penetrates and what regions, that it makes to the blood streams (Se….?) later argues for a late onset which from its earliest beginning did not begin through the blood stream.
Assuming the fungus-like structure or the bacteria with the hints of fungus such as Candidiasis – although mainly if not exclusive from plants hence a construct for fungus – penetrates the walls of the body by action and help of histamine that naturally help the penetration of the walls of the cells since like CD4 they operate on the surface, would mean that the IgA through IgE gradually mount reaction to this fungus in such a way to suggest that structure travel first from IgG less environment since this particular kind of antibody only surfaces in the life on a child after the first 6 months within which Candidiasis generally penetrate the child’s system failing to fully show its given the hundreds of other bacteria that reach the child as well.
HIV is a virus that invades the body is an infection largely for what it does over time to it, that it can weaken the immune system is a fault that is not exactly of its own making. It is therefore necessary to incorporate some of the assumption in the piece by Deusberg that the some bacteria do in fact remain dormant, and here confirmed by the authors of the Magic Shot, these viral bacteria affect passing a process of chromosomal exchange, end up producing viruses that are familiar with a system. In this case, we invoke the thesis in the earlier our earlier composition that perhaps second premise, that the Virus may have started its journey as something other than virus but gradually ended as dangerous to the system due to changes that gradually take place when the CD4 is said to be at its lowest end.
In some measure, the role of viruses entering the body either through the mouth which is usually the causeway of most live virus into the body are naturally arrested by Alpha Globulin IgG, which mount the initial defense in the body and along the respiratory tract and into the gut of the intestine and mucosa, and they are usually found in the tears, in mucus, and in the intestine where they confront the new arriving viruses, but then the body’s lymphocytes and lymph cells produce proteins called Igs, Igm, that gradually react to these new arrivals and are mostly found in the blood, then it moves….the last of these immune-globins are the biggest and these are the arresting houses of some of the bacteria that die naturally or forever perpetuated in the system through the control of the cells.
List …….
From the above instances, we can conclude that some of the changes that arrive at the Candidiasis or the earliest immune related to ‘candida albicans’ and sometimes by other species such as C. Trophicalis which are naturally supposed to be harmless may become virulent affecting several parts of the body, invading the cells, including some of the mast proteins and basophils, creating conditions of osteomyelitis (muscle-skeletal disorder), skin rashes (some of which are comparable to Sarcoma), whacks the central nervous system (meningitis),…..“Because Candida are normal members of the body’s microflora, their presence on mucous membranes is tolerated by immune system, and the inflammatory reaction induced by hypersensitivity response becomes a chronic condition. This reaction may remain local, at the site of dense colonization by the organisms, or became systematic and affect any organ system in the body.” (Joneja, Bielory, Understanding Allergy). Allergic reaction to be sure is triggered by many things in the body, but when there are instances of chronic candidiasis caused by Yeast-like fungus usually remain dormant from birth but gradually and eventually reappears when there is a less presence of the cells that control them, for instance in the case a competing bacteria all of which attack people from the earliest years of the child conception and delivery to about 6 months after delivery. It is the presence of some of these bacteria based complexes in the body, many of which reach the newly born from respiratory tract that compose the transfer and translation of these bacteria into highly favorable and systematic protection that the body needed.
The Arrest house of the lungs raised from Verghese points to this very fact that various diseases are kept under arrest by the body and y the actions of the Chromosome 8 until the defense system is broken to the point that the body can no longer synthesis, split and condition these viruses. This example in the way they cited in this account do not fly in the face of other accounts or in the presence of the claims made by Verghese, regarding the introduction of Cortison into the body whereas it enables the body to fight off cold of some types, it leaves the body essentially vulnerable to increase in bacteria and fungus once dormant in the body. This results from the depression of the immune system by the immunogenic, unlike the type I, type II, type III and type IV, defense mechanism we regard the structure of the cell and its ability to manufacture immune-globin and its response to foreign antigens are reactions that are derived from the presence of the lymphocytes’ protein and the reaction time necessary for the body to overcome.
Using the example from Joneja, Bielory, the ability of Candidiasis to make this comeback in the body is due in this case to combination through types of defenses the body could mount. That in the case of the fungus-like structure of candidiasis it has the ability to withstand the first round of the attacks by the body, usually in the intestines and the rectum, for here the body’s first lines of defenses are in the mucosal where histamines that help to embellish the chromosome and the actions of the CD4 in the body, play a hide and seek game with what looks like Mucous in the body, hence Candida which ‘…are normal members of the body’s micro-flora…on mucous membranes is tolerated by immune system, and the inflammatory reaction induced by hypersensitivity response becomes a chronic condition.’
There are from earliest entrance into the body of the child part of its mechanism, to the point that their reaction to the system is based on human less the body tolerates them, depends on the presence of competing bacteria and foreign antigen which Chromosome 5 is very good for – at least towards conditioning their own complexes hence composing the degree of tolerance by the Chromosome 8 and the human immune system. These exposure that a child has a young age is perhaps good and bad, would not have mattered where it not for the tripping in the defense system, some on account of the cold virus and the other, on account of the presence of other chemical element which the body naturally produces. Brightly speaking, even a sugar complex may create serious immunogenic havoc when in excess composition in the body, and when the body can manufacture.
Here we paint a quick brush stroke on the early papers on this virus; New England Journal of Medicine published in 1981 with title “Pneumocystis’ Carinii Pneumonia and Mucosal Candidiasis in previously Healthy Homosexual Men – Evidence of a New Acquired Cellular Immunodeficiency.” This caption more than explains the convulsion involved with the new virus, it throws light on what they consider to be the more evident ….with the virus, that it is above all ‘...a new acquired cellular immunodeficiency’, means that other forms of immunodeficiency were not unknown and not unfamiliar with Sciences, that it means to suggest that was exclusively common among Gay at the time, admits the problems of demonstrating that among the early cases were Haitian immigrants. However the weight of the material in Haiti was no nearly as profound as it became some time later, that it means to suggest that Haiti got a fair shake for allegedly harboring the killer virus, also throws some light on what early theories could really do in the later studies on a virus and its pathology.
We might cite some examples that experiments between human and primates were performed extensively in Africa in the 80’s, with added expectation that SIV passed from Primates to Humans, that blood samples from monkeys and Chimpanzees were missed SIV and injected in human bodies, and the results which many early enthusiast hope for similar failed. SIV from these primates injected in human and conditions over a period of six months, did not material a zoonotic of any familiar kind, including the hints of HIV. We point that when blood contaminated with HIV were injected into primates that mounted immune responses. To a point that among the earlier experiments on the Zoonotic pathology of the virus, is the aspect of injecting the bloods of primates infected with a bacteria such as plasmodium from any number of mosquitoes and the blood introduced into human beings, there was no side effects saving for the interference with foreign heme from primates. There other human fever causing bacteria and viruses that were tainted by the pro-phage and introduced in vivo to primates, vice versa, and both parties mounted immune responses. From these early experiments that failure of understanding the permeation of one’s immune system by a single virus pre-occupied the minds of even the most adept of all genetic engineers and molecular biologists.
We may be sure that the story of that vaccination do not have to fly in the face of Hippocrates (Greece) ‘father of medicine’, 1527 ‘Jacques de Bothencourt of (France) that gave the name venereal to sexually transmitted diseases. We are here as we were there, that in 1530 Girolamo Fracastoro (Italy) gave a new name to Syphilis which was in 1530 a not well known virus that purified human flesh particularly their prized private parts. Syphilis and even Gonorrhea were latter day names to well-known sexually transmitted diseases whose names became a house hold in the analytic measures of Louis Pasteur, is small which was no well conquered until a medical breakthrough of vaccination.
Then as now, the medical societies has rolled its sleeves on some of the most daring of challenges, one of which is Small Cox that grim ripper that bested the young lives of many abled Europeans. We are funny to mention that the Africans and the Asians with their long and estimable memoriam of the styles and systems involved in dealing with small pox, through variolation, it won’t be funny going by the decided nature of Edward Jenner of England and experimentations that the vaccination against small pox was possible because of him. Now as well then, the motivation is seeking a cure of a virus from the novelty of existing pre-dead or a parent or host of a life of a cell, by re-introducing the elements of the causing agents into a healthy body to placate the profligate viral cells, the body manages to arrest the development of foreign and enemy cells by incorporating it into its system the living verdure of the intruder. The only difference is when by experiment and experience would it be fitting to expose the body to such baby viruses or adult viruses, to form a kind of defense mechanism which is best understood by what we call immunity.
What is Immunity some may ask? It is the ability of the body to mount immune responses to foreign and threatening influences by processing the DNA of the living creature and almost like food delivered to its system. It incorporates the cells of the foreign anti-gene into its life structure. This is a well-known fact and it’s the subject of many experts interested in curation, especially the new methods of gene therapy and blood and tissue transplant that has offered some light at some end of unknown medial challenges. This is in fact true, so true that if it was not, a vaccine for HIV would have grace our markets long before now. It is here more than anywhere can we spy the final triumphs over HIV, since as I have argued and no one perhaps known to us and myself, that HIV is in fact a cell by itself mounting in of itself its own immune responses to human envelope cell based system. How come? The question is also the answer, for how can anyone prove otherwise than re-interpret my own thesis in candid light of the male factor, which is not necessarily overstated or requiring early cases of HIV virus to show for it, which in this case, requires an understanding of biology and genetic studies to gradually enter the dragon here.
All and near medical breakthroughs since the advent of man, all victory over all kinds of all kinds of disease- causing agents follow this replacement pathway, either emasculating the progress of the virus through capturing its viral DNA and capsid as in Bacteria, or by injecting a deleterious chemical into the body artificially reduce the infection and sickness. All of these can be enhanced through the physical and nutritional support to the effective system. All medicine, especially diseases related, it’s really a means to an ends, not to be confused with Watson’s ‘like to like’ or ‘likes’ to the opposite which was obviously wrong in interpreting the DNA structure, rather the human body like all levels of cell structure evolve through replacement process, and due to its evolutionary opulence to new life it attracts foreign cells which are sometimes detrimental. This is evolution almost as if to suggest that immunologic of human body is the root of its evolutionary pathway.
Louis Pasteur in France understood fermentation and ended up doing a great service is isolating the bacteria for Rabies….sometime in 1885. But in the United States, almost to a miraculous endearment, there was a discovery and a breakthrough in sexually transmitted diseases by Phillippe Ricord (U.S) separated gonorrhea from Syphilis. Albert Neisser (Germany) Isolated the organism that causes gonorrhea (1879), 1880; Charles Laveran (France) described Protozoan parasite of malaria, and 1882, Elie Metchnikoff (Russia) was able to separate the Phagocytes in the White Blood cells…Anti-bodies called immunologic E binds to mast cells or binding of IgE to mast when complete, the body releases a massive dose, of histamines….bacteria can inhibit the binding of IgE to the mast cells, - and histamines are not released and therefore no allergic reaction.
What a shame that Vaccination is based on old medical turf gives the impression that we know to expect from viruses. But it seems that the initial runoff success from the time of Onesimus from Senegal, U.S Army and the George Washington’s Orders for all soldiers to be vaccinated against small pox, some advances have been achieved in vaccination, but the chief instrument of the exercise which is variolation has not really changed. Edward Jenner credited with the discovery of vaccination added some measure of medical practice that is not new or started by Jenner. But being able to describe the process in such a way that it became a standard practice earned him a place in the history of medicine. Using the virus to wage defense against a virus is not exactly complicated a process, but the process is the root of some of the greatest breakthroughs in Medicine, especially in ho some bacteria and some viruses are able to empty their capsule while attaching their DNA to the host. It was not solved until the age of crystallography and the event of Watson and Crick.
This evolution requires a better treatment, but to a point that the influenza of the World War I and the attachment of some young doctors in administrating the flu shots and what they experienced with respect to the delivery of the injection, presented the first major problems of vaccination with respect to Alexander J and his Penicillin. However the events where over-shadowed by the Polio virus which defied nearly a half century of medicine in US, suppressing the discoveries of Griffith and his ‘transforming principle’ which Oswald Avery took over. We may consider these periods as quite important in vaccination given the proof that it was the baby versions of the virus which as nothing but RNA that are attached to human DNA is such a way that the structure of the Virus from the Mature version would no longer be required.
Not until World War II were they new demands on the delivery for the best approach to vaccination which was tackled by Rockefeller Institute in New York and by Thomas Francis (?). It is interesting that one his assistant is a doctor that will become central to the dissent over Polio, and this was James Salk. For nearly the last 100 years, the whole Dogma of vaccination is simply used and improved from older systems of first identifying the disease, then the causal agent for instance the Germ and then isolating the agents which Louis Pasteur and August Weisman clearly showed was bacteria. Isolating the soma from the Germ and isolating the bacteria allowed scientist to replicate its process and re-introduce it to the system. This was classic Pasteur and had been used with effective respect to the fermentation very successfully. The whole course of the various cures and vaccination or inoculation – using life viruses – of nearly all competent diseases and severe cases of hormonal breakdown has been met and repaired by Scientist until HIV. But this tug in the arms on the Practice is no without history and explicating it is in Darwin and some versions of evolution history.
Using Victoria A. Harden ‘(2012) historical précis on the origins and pathology of HIV , “…humoral immunity is made up of immune system cells called B cells (because they originated in the bone marrow.) When a B cell encounters an antigen, a molecule or substance that is foreign to the body (such as invading virus), it engulfs the invader to another immune-system cell, the helper T cell. The helper T Cell secret chemicals called lymphokines that enable the B cell to multiply into plasma cells that secrete specific antibodies, proteins used by the immune system to identify and neutralize foreign molecules that lock onto the invader. The helper T cells also trigger the development of memory cells B cells, which “remember” that particular invader’s immunological signature.”…….”Cellular immunity is the second arm of the immune system….T Cells (named because they are processes through the thymus gland as they mature) are also activated when macrophages “present” an antigen to them
It is not the first time that speculation has led scientist all over the world into unknown areas of interest. At the beginning of the AIDS epidemic in California where the first cases of the Virus were made, much attention of the scientist were in the area of the virus as possible related to Cold Virus and much efforts are the beginning of the epidemics especially in 1985 when it became national problem, were centered on the nature of the Virus and its mode of transmission.
Anthony S. Fauci “We may not ever have an AIDS vaccine in the classical sense of being 95% protective….We still don’t know how, why, or if a body makes a robust neutralizing antibody and T-cell response that can both block acquisition and prevent diseases progression. The reason we don’t know this, is because the body doesn’t do it in natural infection. With other viruses nature tells just follow me and I’ll lead you to a vaccine. With HIV, nature is telling us if you follow me. You are going to be in trouble. We’re going to have a push the envelope with HIV vaccinology in ways that we never had to do before.
I feel that as we problem the scientific secrets of HIV, we may get there.” (First appeared in Victoria A. Harden’s AIDS at 30 A History),…and by estimate the direction of the various seem to have changed from its earlier emphasis on the Gay to equatorial forests of Cameroun…where a certain Chimpanzee and some mentions monkey were said to have carried the virus…where some of the older strains of the Virus where discovered. His statement simply echoed the fears of others that we ‘we are unlikely even to know all the details of the births of AIDS epidemics’
I, for one, met Fauci in New York in advocating a different Glentil product and there was the occasion to speak for a new product by the Pharmaceutical Industry. The meaning behind the effort made by these Pharmaceutical companies towards the Non-for-Profit organization is that sponsor projects towards new found prescription drugs, and for that there is little independence on the part of the part of the Chairpersons of National Agencies such as NIAID, NCI, and OAR, which may receive additional fund from the State and from the City but the large operational dynamics of the Medical Campaigns including Cancer and AIDS sometimes force the agencies to look for assistance.
Victoria Harden (2012) pointing to Africa and describing some of the basic HIV types associated with Africa, seem to summarize her journalistic inquiries and historical analysis on the success and failures of several new drugs…..There are other grants by the State and the City….
Multicounty AIDs program (MAP), International Olympic Committee, PEPFAR – President’s Emergency Plan for AIDS Relief, FDA, NCI, NIAID (National Institute of Allergy and Infectious Diseases) headed by Anthony Faucci, CDC, and PHS, NCI director Sam Broder, Up John CEO Ted Cooper, Aaron Diamond Researcher David Ho, Fred Robbins, Frank Volvovitz; CEO of Micro-Genesys – Phase II, CDC, and the committee for new trials on HIV backed by Fauci ‘Micro Genesys AIDS’ and the phase I – III, of the AIDS VAX, which are roundly used in California ‘Vax Gen’ and the Vaccine Alvac-HIV. From 1985 – as some people has pointed out – that attention shifted from gathering information on the Virus which preoccupied the minds of the doctors in the early years of the discoveries to something else which was the rumor about the strain of the Virus in several labs in the country.
After much exposition on the subject and the respect to the six Haitian immigrants who were believed to have had the Virus from its early years, in addition to the fact that two major individuals responsible for the discovery of the Polio Virus vaccine, Jonas Stalk and Albert Sabin, where still alive and active in the science community, the focus of most scientist moved from gathering information on the mode of the code virus and why it was affecting mainly Homosexual or Gay men initially to the source of the Virus. I
t is not wrong to look at the source of the Virus since our knowledge of its origins may have armed the doctors with right tools on how to kill it. But this theory of finding the source of the Virus should not have for instance replace the best of practice of sticking to the objective information on HIV, that HIV was giving us symptoms of being a kind of harmless virus on one hand but delayed onset suggests that it was in original nature not without potency.
Something must have conditioned the Virus in a softly but yet deadly manner, as if the virus like Cold virus has passed through some stages the virulent to the less virulent becoming an entirely unknown element yet all the DNA intact reproducing and undoing the whole system. HIV was not perhaps passed over as a cancer – personal position – since it is not exactly connected to any decay of the cells saving the shortening of the blood efficacy through the badly placed or disfigured three dimensional blood cell protein and the diminishing role of Thymine largely manumission for T-cells.
But like blood cancers it strangles the immune system by dissolving the thymus structure through a galactosides sugar complex manufactured several bacteria capable of living in the gut such as E. coli and Streptococcus, each capable of forming two headed phages immersed in the protein core of the host. Yet their presence which is a factor for life, which enables to life the help of cells in of itself hence lie dormant as if never triggered, yet profligate in a life form far from original process.
We have to credit the Chief scientist in the field, Gallo, Montagnier, Simone, Gaaf, for mentioning that the death of many T-Cells are attributed to the profligate HIV although it is linked to it. We may add here that the constipation of low blood bearing oxygen and the suffocation of Red blood cells, which trigger the death of Thymine due to poor release and reproduction of Sugar or Glucose depended thymine and therefore a shortening of T-cells which actively engage the HIV virus (that does not kill you) only in my understanding and perhaps like others, that Thymine recognizes a chief interest in the virions of HIV, that it is not without an interest or near sexual attraction to it given its primitive origins, but cannot destroy it for reasons since a version of human thymus cells its perhaps buried in cell structure of a virion wrapped in its core by human protein.
In long lasting medical explicating, the virus continues to profligate inside the cell without the acquired DNA which is RNA+ and human protein built from either a bromide thymus or thymus though the primary engine of life, alters the combination of Thymus to these foreign element by reproducing similar Chemical bonding no different from those from a larger and more active covalent thymine from human cells structure.
In a common and fanciful way of looking at it, like terms or chemicals like exact composition do not attract. Magnets with similar polar tugs do not attract and when a protein core wrapping a prophase bacteria or Viral DNA easily create a gap between the covalent bond and link, shifting the three dimensional blood complex and crystal, forcing the body into mood swings similar to sickle cell and to some degree blocks the proper function of blood and oxygen in the blood. It is a slow gradual cancer of the blood, that attacks the thymus since it is originally foreign and needs to mate to speak but like human cases, the CCR5 end up introducing gaps in the covalent link between the foreign entity and the CD4, the thymus denatures and the system is porous. Biologically, most cases on HIV – not unlike Cancer – usually die from other things and not really the HIV which is a blood sucker.
In every sense, it is perhaps an argument that more than the cases of the viruses or bacteria that were drug resistant and more than the cases of the Kaposi cancer in men from New York who proved immune to treatment, better than the facts about the Haitian immigrants who were not themselves Gay or Homosexuals, there was something about the Virus that was ultimately in the sample of cold Virus or an Influenza. There breakdown of human immune system was the first act of the Virus, it was in fact one of the last acts of the Virus which has successfully encrypted its existence in the cells of the host, and there was damage to the body from drugs taken to cure the virus and the final results were a system reduced to a self-destruct.
So we may have erred from the beginning by looking at the late stages of a Virus life, and may have started to look at how the first persons diagnosed with the HIV Virus was done when the virus was already in its maturity, for sure there was the dry throat syndrome of cold, there was the coughing and cold and victims being occasional wrapped in blanket and there was the rashes, all consistent with mild cases of Cold and fever. If emphasis on why the cold fever virus or symptoms where to continuously play a hand in the overall business of the early experiments on HIV, perhaps the answer staring at our face all the time would have been observed.
The incident of the blood testing between humans and primates, and the role that plasmodium played as experimental dispatches on early immunity compromises, between the primates, absorbs all of us of the common theory that the most active elements in the blood types of these primates, follows a pathway that meets the structure of human brain, meets that speaking ability or mental compartment of human being, and the ability of human beings to remain cognitive after so many years. It enters the connection between the faculty of human beings and the production of very active enzymes - either restricting certain cells to profligate or serving as a form of instrument towards waste removal from the body – in suggesting that a connection between the mental capacities of humans and the blood types may be a lasting results of the testosterone and the accompanying enzymes, that it mirrors for instance that men who are castrated as the puberty or thereabout, assume abnormal behaviors that early ends their existence.
In practice and as one Pepin pointed in his book, there seem to be connection between the short lifespan of Eunuch in places such as Africa – Ethiopia to mention – and the castration which leads to poor performance of these enzymes in the body of the male. Sponsor the claim that the blood types play a role in the formation or inception of any virus, it makes it clear that the between what ….
But Ethiopia has its own history……
It is reasonable history that castrated Eunuchs – not just in Ethiopia - do not live long, usually suffer from assorted sickness, ranging from constant depression of the immune system or cold to dry lips and sometime fever, sometimes they experience tears and abnormal emotions almost sinecure to the female while they are still male. Tears and emotions for nothing…. There is a part of them that has died or forced prematurely to denature and this is the testosterone.
But the theory is in Imhotep (the conclusion; affirmation) ….’‘the power of the man, the power of his dick’, a lame translations in light of today’s literature….Imhotep was a human being and was perhaps a Royal long serving and distinguished Egyptian Secretary, organized several academic discoveries into disciplines such as Architecture, Physics, Medicine, Chemistry, etc, but couldn’t have lived for more than three hundred years since many dated sayings where attributed to him long after his death. Imhotep is three words or letters describing ‘understanding’ or a QED, but may be a seat attributed to him following a distinguished career to Egypt and pursuit if wisdom. Im’ho’tep (our understanding) is probably the same as Amen’hotep with a slight difference, the latter is well known for its appearance in the Bible as Amen or may it be so, or we affirm this to be so and so on, the latter arrived in Egypt at a time when A letters were replacing the original K which is probably the first Egyptian letter.
But the real theme understood by the Egyptians and perhaps others, is that life of any human, and in this generic case; the man, can be understood by the quality of what comes out of it; the Spermatozoa. The elder a Pharaoh of Egypt the greater his prove that he was still virile. The more the land tanks the more the Pharaoh is expected to prove that he is not responsible and would demonstrate his livelihood and its spiritual awakening of the fertile earth by coming upon the Nile – essentially masturbating until he releases his spermatozoa on the waters, usually a public show privy to a few select priest and elders. If Pharaoh’s fertility is the power of his dick, if it comes very richly, the pharaoh was still called fertile, he will be absorbed of the short period of draught over Egypt and he can consolidate all that through a marital consummation and a child, a new and fertile Egypt.
When the Pharaoh is no longer fertile and the land no longer at ease with new and abundant crops, the Pharaoh is expected to pacify the land by taking his life, or entrusting his death to the Priesthood. A Pharaoh who cannot procreate or impotent, need not disclose, need to keep the land busy by traveling lands afar or engaging in raids to keep the mind of people from the leathered course. Ramses II – Egyptian greatest propaganda Pharaoh ensured his legacy by constantly having children even in his 90’s, although the severed neck of Ramses III is a different story between a possible assassination and the tradition that is as old as Egypt.
This short dicta beguiles the examination of the power of procreation within the male testis, to be a beginning of the procreation, that the first organic changes that could take place in life of living creature begins to take place in the male, who should be called male and female having the ability to produce both X and Y chromosomes, showing that the female is the X mistaken as the default human, but to the ends of the protein which is not DNA, it leads back to the centromere that the DNA or human genes is as primitively described by Erwin Schrödinger is a ‘code-script’ that has the clearest definition of life, that this life which manifest as a full grown human body is a product of repetition of this code-script or DNA, which in his definition is merely an addition, a kind of building block achieved in clearer fashion By Watson and Crick as the Protein.
The X protein is a cheaper version of a process that is intermediate between Erwin Chargaff and the earlier ascription of Hans Spemann ‘exclusion principle’, describing what happens during mitosis, the new cell acquire new chromosome by excluding what it already has. The X proteins has no life on its own, it is a youngest or the most advanced form of proteins, it is therefore further away from the primitive Y chromosomes, that men inseminate in so far humans as concerned is no co-incident. But the female exist only by the exclusion of genes inherited mainly if not in my view only through the father, making possible future mothers acting with the Y but not able to reproduce it.
The safest way to highlight why HIV as a two-headed prophage or Viral DNA which must began its journey as bacteria, possibly a control or inhibiting factor largely dependent on a mature operon, but bacteria inhibiting factor at a primary stage such as streptococcus or in mordant association E Coli controlling versions of other bacteria or fungi without walls such as Candidiasis, that both Streptococcus and E Coli trapped in the guts of the humans or most creatures, both of which contribute in part to human’s digestive process, both like Candidiasis can invade the walls of mucosal membrane twig-like appearance and retain their DNA in the formative of new Sperm.
It is not the liquid (Seminal Fluid) that can be attributed to be a messenger or the information bearing RNA, but the very DNA of a human being as experienced in the long studies of bacteria and injection of DNA from one form bacteria form to another, is similar to Spermatozoa and its flagella, as if on its most minute and multi-celled super-structure, the Sperm is merely on a male parent body. It is this Sperm like F-factor bacteria that injects its essence (DNA) into a pack of advancing or advanced proteins – mainly the X proteins in female, retained in its embryo as the egg – that empties its DNA into the XX egg protein composed of mainly a parent from similar XY male ordinal, but have no F factor, cannot inseminate itself because in my view, it descended from the Male so to speak her father but a second version of the same line which can only or at least most of the time, recognize the male counterparts which bears the original DNA.
But the male body is active and continuous, it reproduces prolifically, its end product are a retention of a three months of body fluid and mineral consumptions which always includes the bacteria and some endangered chromosomes from the paternal lineage and are all conserved in a protein with DNA attrition, the Sperm and the Seminal Fluid from its testis. Here, in the life of a given creature, the process of protein synthesis and absorption navigate between the presence of a male-synthesized protein – unlike the females or foreign antigens which can still be broken by the human body – the male body lacks this ability to synthesize male advanced proteins containing the original DNA from his father and mother by induction, will prove capable of holding its DNA as part of human male spermatozoa which made its way into the body of the male leading to a possible two headed RNA+ Viral DNA, which makes its way into the new man’s spermatozoa.
Ultimately the three to four factors of the GATC which has been studied towards the manufacture of drugs which for instance regards to patients of ADA, Adenosine deficiency whose immune system from birth – even without the reversals from arrested viruses – seem depleted to a point that they unlike those with damaged immune system from the danger virus, end their lives as early it began. One of the examples of these viruses that can create more than one havoc in the system is EBV viruses and which damages the mononucleosis of an individual can create conditions that arrive the Burkitt lymphoma among the Africans (Magic Shot) and can create the conditions familiar with ‘nasopharyngeal carcinoma’ a cancer that is familiar with Chinese adults.
The book mentions some of the diseases that are arrived as a result of other viruses and bacteria which over the years have laid dormant in the body by invading region in the body that tolerate lysogenic bacteria. The fermentation of these bacteria inside a body and in the regions where they can survive allows the bacteria to shade some of its proteins without removing the Nucleic Acid which is central to its formation, but by incorporating the information from the foreign body into own chromosome, means of retaining its active existence in the body, through self-destruct management, and may remain what may be called friendly to the system over a period of time.
When in 2007 Merck announced that HIV vaccine (V520) was a failed experiment, that it was tested with HIV negative people who became positive in terms of the vaccine, the problems of who was used for these experiments became a public issue. But not the answer is that some stories about the East Africa and others from Africa, who seem to have started the Virus, took a bolder and more defensive show. That these people who brought the Virus to humans were not without blame, and this should also cover the candidates that were used as genuine pigs. Majority of these guinea pigs, either from estimates drawn from science community or inferential correlations of the supposed early years of HIV – dating in one instance to 1949 – in Africa, may equally account for the high presence of these viruses in South Africa, in Congo, in Rwanda and many parts of the Continent direct associated with so-called Chimpanzee theory. It is this not the medication that should run the gamut of the studies, for at specific levels we have the doctors for it, or the specific studies of designer drug product which follow the same track in the body, of different name but similar function.
These pre-occupations may either result from the stigma associated with HIV patient or the failure of any victim justifying why he or she should contact it or suffer it. But with breach in public activity and personal restriction to those with the virus as we find in Ervin Magic Johnson, the virus like other diseases can suffer a natural death. It will not be the first time that a condition such as HIV has showed up in the history of world. There are similar cases involving the disappearance of communities of interest in the time past, some of them like Carthage other than the defeat suffered at the hands of Cornelius Scipio and Rome was at some point decimated through a form of immune deficient diseases or affiliation. The cause of that disease was not known, but like the Spanish flu at the turn of the 20th century (end of 19th century), the disease came quickly and ravaged both on the ship and on land. While the Spanish flu was airborne it was also waterborne.
The Spanish flu was no different from Bubonic plague in devastation, and the reasons why these infections took on a life of their own was the lack of diagnostic of its origins, why it started saving the ships mates brought the dead to the shore, or how it spreads saving that it seem to many an air borne – that is, those who came in contact with the infected also got the infection. The animus of isolation and quarantine proved a diverse that broke the vicious cycle, but like leprosy and its age, many people were blamed for the problems of these infections, some of whom were for instance Jewish, who were blamed for the spreading leprosy, poisoning wells, and for spreading the Black Plague. Not all doctors in the medieval ages agree that it was one group who coursed the virus to profligate, rather the virus is a pattern after people’s way of life, and such small attention to sanitary conditions were taken seriously. Without finding any cures for these diseases and conditions, these diseases gradually gave way.
The main point is that the spread of HIV is only through the metabolized plasma of the patient and a form or formal DNA, and could not proceed any other way saving through the use and abuse of medical resources or through contact with blood. This last point is the bases on Randy Shilts ‘And the Band Played On’ where he chronicled the early years of HIV and provided the detailed emphasis of Gaetan Dugas who considered ‘Patient Zero’ or the first clear case of HIV patient and who according to Randy Shilts consciously infected many other men, especially Gay men. The book has inspired a lot of attention and a lot of other books, some of which were written by people already got the virus including sororities determined to walk in between the line of cure, experimentation, and infection.
To no small measure was the public perception of Kimberly Bergalis who was considered a virgin and had not used a blood transfusion charged towards protecting “innocent victims of AIDS”, that attention shifted from understanding the processes involved in the virus replication to blaming groups of interest for instance Gay men who in turn pointed to Africa, the later as we learnt through history and chronicle of the virus became very early one, a hotbed of experimentation. It is not a coincidence or should we pretend that the blame game in the middle ages set against a minority Jewish group was not set to absorb the rest of the society of the blame of diseases that follows its own circle and feeds on human beings. It is common sense that some diseases are genetically disposed of, but majority of infection are not, and the initial is not transferable saving through procreation.
In no wise different is the contagion of HIV, whose life circle is no confined to a region or people is badger for Africans from the deep recesses of the Congo, for it is only in the names of origins of the virus can medical companies use and abuse human beings through injection of vaccine below the acceptable risk of new drugs. There has always been the issue of a means to an end, where some protagonist cited documented cases on drugs or new vaccines introduced into a public or working society and despite the many deaths it caused; it proved a salvation for others. It is a case that points to the Tuskegee College experimentation of Black male from Macon Alabama who deliberately injected with Syphilis and left untreated for sanctioned groups to study the effects of untreated Syphilis on human body.
One of the things I was privy to is the suicidal behavior and tendency of the victims leading me to understand why in the end, preventing the expansion of HIV was both dependent on the conscious decisions of the diagnosed and the attention given to the lifestyle on those either not sure or those with redoubtable status. The later may account for obvious cases of HIV transmission some of whom understand the implication of their lifestyles but would rather play ignorant to a HIV than face the emotional injury and social stigma associated with recently diagnosed. It is not enough to claim that a socials stigma for HIV is not as strong as may have been suggested, it is however a state of mind that welcomes the cure is not yet available that leads to doomsday psychology. Majority of the emphasis on this virus and patient is created in such a way as to suggest that it is the sexual activity of some group of Americans, for instance the so called Gay or Lesbian (?) or the African Americans whose nature is prone early healthy sexual life, are those who are major players in the spread of the Virus.
The other such as the Latino and Hispanic community has also noticed a spike in the new cases, largely for the attempt at testing for the Virus than other means. But in the end, the last two groups receive the highest blame for the spread of HIV, whereas, anybody can infect others or infected by others. These stereotypes, particularly the problems of expertise of the field, Doctors or Nurses or Health Care experts, loathe observations by nearly anyone without a badge of certificate or honor. As such only those who caught the Virus and those with close family member with the diagnosed status that are interested in the learning about HIV with a degree of interest. The rest of us are incurable expat on opinions and diagnostic made available by those in field, but by condition of more direct investigation of the Patients and their drugs, we are able to see through the understandable but proud-ridden closed-off of medical institutions; CDC (Center for Disease Control) and private medically experts each seeking in their own ways to find the cure for HIV – one of the Viruses that can lead to Immune Deficiency.
The reasons why these organizations react with disdain to such things are many, including a possibility of Abuse and use of a medical terms that need explicating to novices, but it seems that the terms and conditions are no replacement for the Virus itself and why more can be done towards a better understanding of the Virus, why it attacks or attaches itself to a CD4 host and why in the end, the Virus overpowers the immune system. The few stories which we remember from the early years of the virus includes one concerning the Kaposi Sacoma which appear in the skin of mostly HIV position homosexual male. The Candidiasis appears in blood groups of mostly Hemophiliac and people with chronic cases of blood thinning and Pneumonia. The transfer of blood played so significant and blood management also played a serious hand in deciding early reaction to HIV and from downtown New York was a man by Michael Rosenberg who dies in 1994 from blood and HIV complications not before founding the Hemophilia/HIV peer Association, which sort at least in New York to monitor blood distribution and donation through the State.
An outbreak of contaminated Blood plasma in Tokyo a decade earlier threw a lot of light of how the confusion between Hemophiliacs, Sickle Cell, and Blood Anemic patient peered off with cases of compromised immunity sped through blood donation and government officials and how they affected people with HIV in New York and many other parts of the country. Whereas the issue of blood transfusion and Plasma donation has been partly common in New York due to a peculiar kind of immigrant entering through its harbor, it never amounted to grave and deciding consequences until there were obvious problem of pox developing in the blood of victims of a supposed newly linked virus. One of the earliest warnings on the blood transfusion came from Susie Quintana who was believed to have contracted AIDS through the process, but the litigations did not arrive on time for her settlement which eventually reached 8 million dollars.
Douglas Starr (Blood; 1998) describes the blood groups and the companies that made it possible for the distribution of the blood around the world in what he described as ‘epic history of medicine and commerce’ where the whole blood is known consisting of Plasma which remain frozen after being emasculated from plasmapheresis which normally aids in fractionation and by necessity of a form of dense cryo-precitation treated with anti-hemophilic factors, and there are cases of Albumin, Reagents, Anti-RH, applied as a contingent treatment but done so slowly that it amounted to level of oversight, and some of the blood hematology used in the time past, containing as they say life forms, in and Red Cells. White cells and platelets…
Like other breakdown in the body and the rise of the duplicitous symptoms of immune-deficiency Syndrome, one of the more remarkable is the presence of Candidiasis in the mouth, nose, in the mucous, and in other parts of the body, including irregular bowl movement, nausea, headache, bloating, vagina itching, the ‘Psoriasis’, purrs from the cell, Coxsackie, ‘loss of energy’, depression, ‘loss of memory’, fatigue, …which are symptoms of HIV, are also similar to the Chronic Condition of Candidiasis Syndrome (CCCS) which like many other lytic cases or cystic, did not have to passage through the blood of foreign donor or enter the body by the contaminated contact, it may remain stasis up to a certain until encounters transmit the changes. For nearly all viruses and bacteria that are capable of invading the body is usually part of the body or part of its immune system, does not mean that all cases which in this leads and yields to formidable virus passage through the same process, but no culture which exist anywhere is done without this process….
In some clarity it proves of HIV as a Virus acting from within is
not far-fetched, it is a fact that is well known, could have died on the first person who made the contact with the virus but like funguses or bacteria, it managed to survive.
Needs to play to this knowledge of HIV from the School of Gallo and Montaignier on HIV, that the attention is not what causes the symptoms but on what causes Pneumocystis and the viruses are observed according to prolonged studies. These knowledge wounds and heals, for if we are looking at the reasons why these bacteria and fungus-like structure are manifest in the body, the main events include looking at the opponent of the virus or bacteria that were once dormant, opponent which includes what it them harmless and why they became dangerous, suggest that some conditions associated with these complexes are permanent and therefore long-live in its harming.
For all these could not explicate on how the virus became lethal over time, assuming like other viruses or bacteria it remains dormant so to speak, and like other fungus-like structures such as Candidiasis, the possibility that HIV is one of those dormant viruses or bacteria would not never be achieved in the destruction of the cells that it finally wrought on the body.
There is no telling that it is acting along other viruses, no telling that other viruses like it also exist in the body to checkmate its movement, it amount to a clear and concise remuneration that the virus did not like candidiasis affect human immune system from a child level or before 6 months old, it observes that the primary attack properties of the virus is set in such a way that it behaves like a dormant Type IV slow virus due to the lax and sometimes delayed reactions of antibodies in the system meaning the last of these defense system, which is IgG which is slow in its preparation given ability to manufacture new DNA but generally built to effectively defend the body and are found mainly blood, complement that HIV has at least more than one pathogenicity, that it has more one elements in its retroviral structure, which could be harmless because a virus or fungus in the body can checkmate on it, and it has a secondary Viral DNA in its nucleus from a different source – possibly as we have argued from human being – which allows to evade the system as if it is a cancer to its system.
Toxicity is Type II defense protein, in its range of relative defense mechanism is the cytotoxity of cells, it causes cancer as we have mentioned where the body enables the development of the cells with its own immune system to wage effective defense war against itself, hence a toxic site or region given above all to the mutation that the cells encounters in the course of its reproduction, it leads to less and less effective development of the cells and then becomes cancers and little enclaves in the body, expanding and consuming all the necessary nutrients it needs to continue its growth and it is said at this point to have immortalized – so much that it spreads from one part of the body to several parts of the body. The enclave is not unknown and the comparison of cancer to HIV is not a new study, whereas some studies
A chronology of CDC’s AIDS definitions
1983
Protozoal and heliminthis infections
(1) Cryptosporidiosis, intestinal, causing diarrhea for more than a month
(2) Pneumocystis carinii pneumonia
(3) Strongyloidosis, causing pneumonia, central nervous system infection, or disseminated infection
(4) Toxoplasmosis, causing pneumonia or central nervous system infection
Fungal Infection
(5) Candidiasis, causing esophagitis
(6) Cryptococcosis, causing central nervous system or disseminated infection
Bacterial infection
(7) “Atypical” mycobacteriosis, causing disseminated infection
Viral Infection
(8) Cytomegalovirus, causing pulmonary, gastrointestinal tract, or central nervous system infection
(9) Herpes simplex virus, causing chronic mucocutaneous infection with ulcers persisting more than one month or pulmonary, gastrointestinal tract, or disseminated infection
(10) Progressive multifocal leukoencephalopathy (presumed to be caused by a papovavirus)
Cancer
(11) Kaposi’s sarcoma in persons less than 60 years of age
(12) Lymphoma, primary, of the brain.
HIV antibodies not required.
1985
(13) Histoplasmosis
(14) Isosporiasis, chronic Intestinal
(15) Lymphoma, Burkitt’s
(16) Lymphoma, immunoblastic
(17) Bronchial or Pulmonary candidiasis
(18) Chronic lymphoid interstitial pneumonitis (under 13 years of age)
Antibodies are required.
1987
(19) Encephalopathy, dementia, HIV-Related
(20) Mycobacterium tuberculosis any site (extra-pulmonary)
(21) Wasting Syndrome, HIV related ……………………HIV antibodies required.
(22) Coccidiomycosis, disseminated or extrapulmonary
(23) Cryptococcosis, extrapulmonary
(24) Cytomegalovirus, other than liver, spleen, or nodes
(25) Cytomegalovirus retinitis
(26) Salmonella septicemia, recurrent
1993
(27) Recurrent bacterial pneumonia
(28) Mycobacterium tuberculosis any site (pulmonary)
(29) Pneumonia, recurrent
(30) Invasive cervical cancer (antibodies required)
(31) T-cell count is less than 200 cells per microliter or less than 14 percent of the expected level.
References
(1) Deusberg, Peter (2003). The Invention of HIV
(2) Selik, R.M., Haverkos, H. W., and Curran, J. W (1984) “Acquired Immune Deficiency Syndrome, (AIDS) in the United States, 1978-1982.” The American Journal of Medicine 76; 493-500
(3) Centers for Disease Control and Prevention (1992). Revised classification system for HIV Infections, and Expanded Surveillance Cases Definition for AIDS among Adolescent and Adult, Morb Mort, Weekly Rep 41 (No. RR 17) 1-19…..
The information on the spread of HIV from its early roots to the ends of the modern times has featured all sorts of interesting notes, and may not be said to have exhausted the list……It seems that some of the infections are not themselves caused by HIV, that the virus is considered by many experts to be close to Slow viruses of bovine and visna but are not saved by the end products which is cancer causative with due respect to the plaque in the cell or what essentially leads to form nerve wracking, decay and demethylation, for that these viruses which may be classified as retrovirus are not themselves dangerous, are essentially trapped in some restrictive enzymes where they grudgingly make all the damage. It the list given to us show despairingly evident opportunistic infection (oi) it may lead us to accept that the tools of coins between the viruses that affect human being when the toxicity is expressed and the ones that remain in the body as friendly viruses, which though toxic but are placed under some binary control by growth inhibiting factor in form of a virus or bacteria existing separately in the body, when such limiting growth factor is tripped or tampered with, there is a presence in the body that proves dangerous.
Therefore it may well be said, that a relationship between the toxic viruses and the non-toxic viruses exist to the enabled degree that as long the count of some virus or some bacteria remain within a certain level, there is a required relapse into the fronting that a once friendly virus such as HIV or once friendly bacteria such as streptococcus are no longer friendly due to their expansion and feeding on the host, due perhaps to the attacks that the body received from the very elements that support both the bacteria or the viruses that directly occupy sensitive LTR regions of protein replication. We may compare that the differences between viruses that are friendly and the once that are not friendly is based on how they profligate in the cell. For if we compare the removal of some of the CD4 from the body due to the actions of the system to protect itself, you have either a body that is recklessly prone to opportunistic infection or in terms of HIV you may have a body that can withstand the virus.
It is an academic accusation that the role of CCR5 in the cells structure of protein, is so vital for the survival of the virions that the reasons exist directly that the role of CD4 in helping to ward of viruses such as RNA + viruses as such Streptococcus that multiply on their own, the CD4 in helping to fight HIV essentially primes the body into a situation that has no escape. In shadow of the discuses on HIV, we may look at the presence of the above diseases in the above charts by CDC, and compare to what extent that these viruses been observed as part of human beings. Nearly all these viruses are not new, nearly all these viruses are not destructive, many of them fungi or bacteria based still remain in the body for long spells of existence, for instance Candidiasis, may only multiply according to the limits which was formerly placed on it. For a fact, the case of Kaposi Sacoma could be called a kind of cancer given the presence of the Src genetic based oncogenic for Sarcoma, that it is characteristic of those who suffer Pneumonia or they call PCP, impales against other facts that these were product of ordinary immune deficiency than anything else, that these men had a lifestyle that included recreational drugs
Distempers medical reaching that it was a new virus that caused AIDS….
It does not mean that a new agent is not elemental to the virus it does not mean that agent is removed from the humdrum reality of the very reasons why most Gay couples and sexually deviant homosexual were the culprits. The virus could have come from anywhere else, also means that the virus may be living its secondary existence with an astute approach to profligate that is similar to one, the viruses that been tripped in its balance –which though should lie dormant in the body and remain as a friendly virus was now virulent given its new ability to spun toxicity. The other group that may show a disappearing comparative between HIV docked inside the cell and expanding, are the very slow viruses that feed off the cells. What from experience in the lab is said to constitute this phase level activity on a bacteria, is based in part on the work done by Delbruk and Sal…., which was carried through by David Baltimore, that plaques – no less or more than what is found in the cells are seen as leftovers of a bacteria or virus expanding beyond is provisions like Algae and some E.Coli left overnight in a flask, where the flask temperature helps to profligate on the bacteria, but in the end, when much of the yellow stains are removed, there is a plaque at the end.
The toxicity of cells when they become title tumors able to support their own existence, or when they become immortalized that cells divide on their own, leaves us several theory that the virus behaves like Bacteria, as if it a multi-cell organism, explicates why multi-celled Eukaryotic bacteria survive on their own and in the body of the host, earning its own requirement from the host within losing its basic DNA or Chromosomal inheritance. For this explains why there is a transfers as Lynn Marquis and Sagan wanted to demonstrate that though there are Eukaryotic cells that have their viruses, it is the ability of cell support its own existence that transfers it from single cells to multi-celled organism.
Playing backwards it is impossible to deny that these movement of a single celled fungi and a single celled viruses, could not support itself own existence saving that it attached itself to the host, that in spite of what we now know as the difference between the S strains of some bacteria and R strains, there is something about DNA and RNA that separate a virus from a bacteria, something about the RNA to RNA dogma familiar with transcriptase that will point to the existence of two separate viruses enclosed in a what is called HIV nucleus capable of supporting itself through the enzymes, operating as if it was a multi-celled that is more than one virus and since the virus and the Amino Acid of the HIV is RNA+ are said to profligate but less than the vicariate and hierarchy of a bacteria, it means that the retro-virus of HIV explains its own history, that life became as a constant addition of two probable entities – the root of which is perhaps the trapped hydrogen determined bonds of a DNA which is itself perhaps two RNA of some unofficial verity.
In elder language, the two RNA that conform between the DNA and RNA and vice versa, away perhaps from the central dogma and Crick and Watson deposition of intracellular hierarchy of DNA torching RNA and RNA to protein, may illustrate that the bacteria as more than single celled, is a product of several mutable Ori sites in the body or derived from elsewhere, perhaps of similar or discolored Carbon electron transfer that affect the sugar construction including those of blood cancers as Insulin misreading and diabetes, sickle or recurrent cell anemia due to porosity of oxygen bearing hemoglobin – itself a defense mechanism – and the externality of RNA antibody that is no wise different from the dialectic of cancer, oncogenic cells and genes, immortalized and replicating to the point that if a man or woman dies during this constant replication and fed by bacteria from without, the body has a way of changing the biological dynamics of the bacteria itself, though friendly may from the zoonotic of human or animal carcass become agents of diseases such as typhoid or dysentery.
The Special cases such as Hepatitis, adenovirus, Coxsackie, varicella, human herpes virus type 6 (HBLV-6), Cytomegalovirus, Herpes Simplex type I, and measles, for these isolated groups of interesting infectious disorder, are well studied and have easily occupied the time of medical communities in the world. Some of these are no longer the first light on the concern of big world organizations such as the UNID, MAP, and the engaged efforts of NIH in Maryland, there are other concerns like those of Malaria which has been reported to have claimed more live than a more primary problem of HIV, and the foundations such as Bill and Melinda Gates Foundations have added luster to the efforts in eradicating Malaria parasites, to providing new tools for vaccines in India on the final notes that Polio is eradicated.
Several measure of efforts on HIV including international corporation working for the general good of the world, are variously involved in the pursuit on new curative for viruses such Ebola which is also recent, viruses such as Measles when and if they occur, and the permuting need for orally delivered live-virus, BCG which the French developed and MMD, which the English developed, along the vaccines here in the United States, part of which is the saccharine and starch passaged and tested cold flu viruses, authored in the United States every year.
In one case worthy of the trouble is the recent breakout of Ebola which is reasonable close to the instances of Lassa Fever - not unlike Yellow Fever – are different on account of the source of these viruses; the first seem to have arrived from Rats and the Second from Mosquitoes, and are quoted by foremost authorities on the subject to have come through Africa. All the named variously are known to have reached United States through Africa and Africa for this reason has been the interest of preeminent scientist of the world.
In Robert S. Gottfried ‘The Black Death’ which was set in order of F.A Gasquet 1893 ‘Black Death’ we find him discussing that “Important as small pox and measles were in the natural history of infection disease, their combined role was dwarfed by the arrival in 541 of a third disease. This was plaque caused by a complex series of bacterial strains called ‘Yersinia Pestis’”, he went on to argue that the Plagues etiology demonstrates ‘Y. Pestis’ toxicity varies, but the diseases is always highly lethal.’, that it lives “it lives in the digestive tract of the host “black flea” while feeding regurgitates into its victim large numbers of Y-Pestis bacillis.” In the end, we find that people’s inability source the mode of transmission of the Bacteria into the body made them prey to the dangerous nature of the killing plague which devastated Europe from 1347 – 1351 and killing up to 25% of the population.
It was most probably inhaled and in recent times, at least at the turn of the 20th century, there was a similar outbreak of Cold Virus resulting in the body of its victims turning blue-black. This Influenza wiped off the people in the Ship and their boat never made to ground and died every one of them on board. The Ship was discovered in some abandoned placed, half docked and crash landed. Someone mentioned that the silence of the crew which included renowned doctors of import….It is possible to suggest that relationship between these kinds of Virus and Bacteria is that the Bacteria are single celled organism that needs oxygen to survive on its own. It can also spread as rapidly as any
Robert Koch settled the issue of Diphtheria, discovered the virus that caused Tuberculosis, but in 1892, in the United States it was Walter Reed that discovered that Yellow Fever is transmitted through Aedes mosquito, and according to Rita Mary King ( ), by the end of that decade, Joseph Lister in England developed aseptic to prevent infections.
Molly Caldwell Crosby 'The American Plague'; 2006, 'the untold story of Yellow fever' for instance describes the problems with the victim’s body as this that "The Virus attacks every organ, poisoning the body from the inside out. As the immune system fights back, temperatures run as high as 105 degrees, and the patient grows delirious. The body gives out. It hemorrhages, running red from the eyes, nose, and mouth. Vomit, black with blood, roils. Then, the fever leaves its mark, tinting the skin and whites of the eyes a brilliant yellow, giving the virus its infamous name; yellow fever" This paragraphs is by many designs derived sources which were popular about Yellow fever and what she however adds to the story is the dynamics of the Virus from purely academic point.
Rare cases of yellow fever in our time are hard to come by and the virus seem to have passed from Mosquitoes carrying a fever virus called Flavivirus from supposedly West African country and spread among the people in Mississippi. That once inside the body of the victims, its hijacks the cell and its 'basic machinery' and would use the cells dynamics to "replace the Viral proteins and RNA, until the particles burst through the cell." In no distant time a body full of healthy cells would in no time be riddled with virus carrying the 'yellow fever virus' and for this process "anything that could destroy the virus might also destroy the cell", she said.
In a World Health Organization rap sheet on Malaria transmission and the Malaria causing Mosquitos; January 14th, 2014, the sheet, clearly pointed that “Malaria is caused by a one-celled parasite called a Plasmodium. Female Anopheles mosquitoes pick up the parasite from infected people when they bite to obtain blood needed to nurture their eggs. Inside the mosquito the parasites develop and reproduce. When the mosquito bites again, the parasites mix with its saliva and pass into the blood of the person being bitten.” The sheet continues that “Malaria parasites multiply rapidly in the liver and then in red blood cells of the infected person. One to two weeks after a person is infected the first symptoms of malaria appear: usually fever, headache, chills and vomiting. If not treated promptly with effective medicines, malaria can kill by infecting and destroying red blood cells and by clogging the capillaries that carry blood to the brain or other vital organs.” These symptoms of the body over-powered by these mating Mosquitos it’s not the same in every person, does not also affect anybody in the world, like the saying goes in Africa, Mosquitos do not even bite everyone at the same rate.
It has preference for blood types, and the rate at which it mounts proboscis on any person sometimes measures the level of demand for a person blood type, that those with classic A Antigen blood group are more than likely to suffer from these attacks from plasmodium, a relay that like Red Bugs and Bed Bugs, the bites from insects can be due to a blood type, and the reaction to these germs in the body can also be brutal if not demanding to such persons including consisting scratching of the hands and the legs or in facial irritation leading to headache. The rest of the problems that warrants death is the failure of an active T Cells from matching the replication of these germs in the body, at a rate that suggest a mature germ which must feed on the host ridden from body of the Anopheles to a different host, in exchange of a blood from such a person.
In all reality, the structure of a HIV positive RNA is digestible by an anopheles that the connection to Plasmodium is not warrantless lead search towards understanding why the HIV attack Plasma, both pathogens or parasites are dependent on Plasma, but the Plasmodium induced Malaria, it’s in all, a foreign entity, that may paralyze a victim for a few weeks but not permanently locked in pitch battle like HIV.
“There are four types of human malaria: Plasmodium vivax, P. malariae, P. ovale and P. falciparum. P. vivax and P. falciparum are the most common forms. Falciparum malaria—the most deadly type—is most common in sub-Saharan Africa, where it causes nearly a million deaths a year.”
“In recent years, some human cases of malaria have also occurred with Plasmodium knowlesi – a species that causes malaria among monkeys and occurs in certain forested areas of South-East Asia.”
In account that shed weight on chain of discretion from older times to now, we may look at the work of Tsetse Fly, and the direct association of the a fly to the introduction of trypsomania to the body which when transferred to second body, causes the blood sucking pathogen to feed on the Red blood cells leaving the victim seek and weak, to the point that the furious replication of the virus in the body led to weaker and weaker immune system and eventually to the death of the patient who was recently infected.
The Colonials in parts of South Africa who died in some numbers because of these diseases were privileged by their education and by the use of stethoscope to fight back on these killer diseases and in this case, there was a certain David Bruce who came fresh from the wars on Crimean fever which was the course of the Malta fever where he isolated a bacteria ‘Micrococcus melitensis’ from the spleen of men who died from it, to Africa on assignment by the English Majesty.
The main event was discovery of the source of Tsetse fly and where he isolated the agent for it. John Mckelvey, Jr., (1973) makes out this history, revealing that the commission to go to South Africa led him to discover that “the Haematozoon or Blood Parasite of Fly Disease” which left what we know as fragment of its DNA on the host, and the DNA proved a blood sucker which the fly essentially retract upon maturation. Here, the examples followed by Bruce David were those of Karl Joseph Eberth, Edwin Klebs, and Robert Koch, and in his time was said to have produced the Sodium B-aminophenylarsonate- NH2C6H4A5O(OH)ONa, all in other of a quinine manufactured by Klebs to counter the diseases malaria.
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We have taken a better look at the leading arguments on the transfer of virus from humans to other primates such as the Apes and the Chimpanzee and a transfer of virus from other primates to human beings in both epizootic and zoonotic biological proscriptions. But the argument has no stretched far enough and it is within the construct of independent human psychology and process of thinking to
It is this entangled web of consideration separating one form to another that determines the left and right of the cases involving HIV and human in context every situation, and above all, in context of the difference between attitudes to blood and body types in names of blood and virus profligate.
The primacy of the blood groups which separate a Chimp from a Gorilla, a Gorilla from a Human, to a narrow a channel of the body’s ability through the nasal cavity to manage its varying degrees of defense system which will help its existence on the merits and demerits of an infection status and use and abuse of HIV as a human virus independent of the environment in which it exist….
This argument has been advanced in many direction and by many medical experts that it is fitting to suggest that nothing remains of the doubts that humans and primates separately suffer from cold virus and influenza, but the components for any of the many primates
Like we mentioned above, there are exception to this situation and one of which can argued from the composition of the highest density genes such those with the only carbon copy of 22 sugar genes. This sugar complex tend to be ranked higher than others with tendency towards the release of insulin in the body, may be relevant in its variation of the population they tend to form and as such a given biological population is probably one evolutionary pathway whose frequency is lower than those of higher density and whose overall number of sugar complexes is 22.
In any case, there is a chance the total number of genes and biological functions that can be discovered in a section of Africa is equal to the total amount of genes – either through mitochondria or through the Y Chromosomal inheritance - to the amount of genes available in all of United States including those of Africans and African Americans.
Total amount of genetic information that can be found in a small city in Africa will match the total amount of genes available in all of Russia and all of China.
As far as Nigeria, it is estimated the Nigeria alone has more genetic diversity than any nation in the world. Why? The answer is well known from all scientific information that Africans are higher placed on the density of gene protein, a fact that has been taken for granted yet probably useful in throwing all kinds of light on why for instance a man such as Simon Flexner was right that all Polio Viruses are the same, and why the attempt that at correlating the HIV variants to animals of the Upper and Lower Apes kingdoms – the so called cousins – is not only misleading but totally flawed.
For sure we may indicate that based on half the process associated with genetic breakdown and studies; there is an equal measure of the distribution of genes in theory which will not comply with the tree version of the variant explication of human types and specie that relates to HIV in all its form. But this variation between one variant of HIV and another, for instance between HIV 1 through HIV 40 and perhaps more expanded as the case may be, may be due to variants in human body and composition of genetic materials in human body.
Let us rehearse some of the information about human beings, that there is a tone of body types and differences between one pool of human genetic information and another, that the races as we have them today and the types of human beings as we have them from previous eras and have seen them from all encounters and from all works of life suggest a composition of human genetic materials and proteins that derive from parents. This is the nature of HIV and immune deficiency syndrome.
No one human is exactly the same in its order of genetic material - with or without respect to any source of vicariate event or epigenetic demonstrated by Jerry Frodo and Massimo Piatteli - Palmarini such that one person at one genetic end of a spectrum is different from the other at the opposite side of the spectrum, that leads from the fact that the differences between humans are based on present continuous cases of protein arrangement beginning from the Meiosis and conception to maturity relevant to hereditary.
I for one, do not need to shed all these light on the present fact that Charles Darwins' theories on human evolution is not wrong, but the pathway he eludes and derives his arguments from do not tow any useful biological construct saving for cases of cancer and deleterious manifestation as mentioned by many experts.
It is this variant that is a product of the many sorting processes in biology and why on primary level humans relate to each and at a certain level they differ. It leads elsewhere that attempt to transfer this minor changes in human beings to primates with argument based mainly on duration, fracture and adaptation, as if the biological construct need no magic to grow given its necessity to survive, is not expected to survive since the time frame separating one primate from another - in spite of archeological evidence is inviolable due to the constant energy structure of the world.
There are therefore no possible new creatures given the basic DNA structures underlining all animals on earth, there is therefore no possible difference between one animal from another in terms of time line and in terms of the age of dinosaurs whose basic animal structures contain as much underlining DNA as does all creatures including Hippopotamus and the varied humans and other primates. This fact need to be understood in other to score any chance of understanding HIV.
In my direct view - based on my many years of studies - nothing can account for differences in human being; both in nature of the races than the speciation of genetic materials. The relevancy of the statement is derived from some favored knowledge of history and from general and specific assumptions about current studies in genetic studies which tend to suggest separate existence of HIV structures with separate origins, whereas these HIV viruses and SIV viruses wouldn't have been an obstacle if we understood the genetic difference as a question of the region which it profligates than separate pathways.
If we can also put some measure of intellectual force in understanding that evolution or transfer of viruses from one primate to another is not easily achieved and may be depended on the particular nature of the virus especially the rapid and fast viruses such as Ebola or other airborne and injected viruses including for instance Polio Meningitis and not necessarily the Lentivirus or slow virus which adapts to its host and vary in its population of the creature.
A lentivirus adapts to its host, like oncogenes from Zaire chimps out of which a strain of the Polio virus was used in preparing the vaccination - cooked or alive. A strain of slow virus from any one of the primates does not easily transfer to other primates saving for direct cases of rapid profligate activity of the virus between gp 47 and gp 120.
Once we have become conversant with a Retro Virus such as HIV and its operational dynamic, it becomes self-perpetuating to relate the number of variants to a process as opposed to Spill overs. Put it bluntly, there is one form of HIV existing in the world, one strain - a personal dogma - that in spite of the assorted phenotypes of the HIV 1-7 (HIV 1-19) we may be looking to a degenerative protein quality of all Viruses as opposed to new types, such that a flu virus mirrors duplicity and its tendency towards new forms from old.
One of the principal reasons for this fast and slow virus profligate in the human body is the activity of the antigens. It seems that certain cells in the human body only allows us to subdue new materials entering the body and the body's reaction to foreign antigens is particular the work of AB antigen and its suicide mission and the role of T-cells. It is easy for Gorillas for instance to withstand any hint of HIV from human beings even as co-primates given the very structure of their blood types such as B blood group only, that they have a longer stay on processing new infection or exposure and may die from SIV, immune deficient related diseases and other versions of lentivirus without notice given the granulations of the B cells and its propensity to condition the virus in their system. These types of viruses are necessarily cancerous, necessarily a leading course of animal degenerate condition such as blood cancer such as sickle cell and HIV which I for one believe peritonea.
The issue of graduation and duration between humans and gorillas can hardly be true, for all intents of understanding that slow viruses tend to split as quickly as does fast viruses that memory cells play important role in harnessing and understanding the nature of these cells - especially in humans - and in animals as the case would suggest - that some of the enzymes such as Cortisone may be a natural occurring material in the body from a blood sequence naturally rich in B cells.
It may seem to suggest that the B part of the blood may have to do with a promoter of some sort and not necessarily a gene that superficially code for any type of blood crystal structure hence what they call memory cells has all the cards in understanding Gallo arguments and Montagnier arguments and has all the points about the reasons why HIV may invade immune system, may lack vaccination, may above all be a virus that has both cells in its mast, especially the human cells encased in the prophage, for instance E.Coli or Pneumocystis which excrete a peculiar kind of sugar (complexes) that dissolves sugar complexes especially Thymus structure in a basic DNA strand, capable of temporarily altering the final structure for hemoglobin and distribution of oxygen in the blood leading to collapse of the protein and death of red blood cells.
There are several lines of defense in immunity complex of any virus and creature - which from a personal dogma is made possible through the testis of the male where the earliest or primitive reproductive processes began.
Whereas no relationship seem to exist between people with ABO blood types and those with Alzheimer’s - a different argument - which is a process of decay and plaque accumulation from failure of the blood to remove calcium or other minerals from the brain and the blood - a case no different dysfunctional blood plasma and oxygen storage and other forms of human and animal structure.
It may mean that those with O bloods in of itself, do not behave like say Chimpanzees for reasons of body structure and composition and those without B type in human beings do not behave like Gorillas for similar reasons which requires minimum interpretation.
If the body fails to remove any major mineral from the blood if settles somewhere in the cells or in the walls of the cells, and over time, it builds up like plaque in the cell and give problems which the body did not anticipate, a case no different from body fats and cholesterol which advanced HIV cases suffer and HIV drugs capable of dissolving these residues in the body also drains the body.
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The relationship may therefore be limited to other factors such as the ability of the Chimp to produce the Sailic Acids, an agent that may have resulted from other genes lacking in the Chimps body as opposed to the primary roles of the Sailic Acid in the body - perhaps regarding the respiratory system given the production of mucous membrane, all of which may or may not be reduced to the 450 missing total genetic information separating Chimps from Human which influence attitude of the body to foreign invention and the regularity of the body's removal of blood from the system.
Some these genes in Humans may be sugars and acids that are available in humans and not in other creatures. But since it is the rooted in the structure of the Chromosome, that is its productive side, it can be said that the basic structure of these Chimps with due respect to Y chromosomes is from it’s probably origins dissimilar from that of the humans.
In essence, a human beings may lack the ability to produce these sugars which suggest a kind of subduction or descent and not nearly ‘ascent’ as in the man, a lower construct if does exist will be a comparison to Human’s closest and richest genetic information reservoir, the Black Male. The African Male/males
We point to an example of the popularity of an idea that has no foundation in biology, that as much as Peter Medawar proved beyond reasonable doubt that some infection do occur during transplanting a part of an animal to another, but he limited his ‘Art of the Soluble’ to immunology of the two comparable set of creatures, that the blood types of any-one willing to receive a new body part from a donor should at least in principle be comparable.
That what was killing patients in England was the general oversight of the blood types, a theme that is not far from enzymes from DNA and molecular arrangement of nucleotides, assumes to be correct in so far as the blood types and groups of Chimpanzees are different from humans and in many ways, the plasma may contaminate but in so far as the promiscuous origins of new virus from seemingly mutant and dormant bacteria, the process is generally a-biological.
Peter Medawar (England) and “did the basic research which brought to light the problems of tissue and organ transplant techniques and immunology – in 1967 – discovered acquired immune tolerance factors that oppose tissue transplant.”
This fetched him the Nobel Prize but also a lasting standard on the comparing the blood types of English patient, there was the limiting issue of infection which was later resolved in America through the demonstration that Histones or Methionine which penetrate blood cells and ease the transfer of blood types, inhibit the penetration of some of the bacteria, in many ways than the one, the presence of Histones which can replace Arginine in the chain of Amino Acids, rich in the three layers in lysine and in the third Cytosine, are mainly and directly responsible for some of the differences between Hemophiliacs derived from parents and Hemophiliacs resulting from an Influenza, for all its intent of purpose and use we can show that the passaging of some of the blood from the blood cells of some of only leads to what is true, that mainly all viruses tiny enough – even at the absence of histamine that penetrate through some cells – are viruses capable of surviving on their own. In the blood types and the competitive K-ishizaka (U.S) discovered gamma globulin E (IgE), which also present at some level in serum? Serum makes its clear…..
There other foundations of Biology and medicine that are important, used in part by Peter Deusberg in his arguments against Gallo and Montagnier that viruses capable of causing epidemic should be new viruses – set in order of Koch – where the theory was also placed in different in terms of (Farr) on the veracity of a New Virus.
While we may indicate that the whole statement raised by these experts are true, they are true to the extent that the body could easily adjust to changes in the body and in the environment if and when the exposure to the system do no prove fatal. It is taken that these viruses capable of destroying the body in slow or speed motive are doing so for many reasons including that the body and CD4 cannot keep up.
However there is no going that HIV is an infectious disease in keeping to Deusberg and in Order of Farrs - HIV viruses do not meet the criteria for infection, adding that the virus is considered a retrovirus essentially to the careers of Gallo, Baltimore, and Montaigne, whereas retrovirus and the reverse transcription of RNA to DNA and DNA to RNA through an enzyme, means that HIV could have been the reasons for AIDS as according to Deusberg, but in all, shows that the total damage that the body can sustain is sufficient to satisfy its healing and its cure so long the exposure does not directly and indirectly kill the system composed mainly of active cells.
For that, there are chances that the bi-product of the human body which are physical and which separate us from each other, can traces of the returning few months and carry viruses and bacteria that the body pushing out.
In practice, the total amount viruses and diseases that can exist the body or at least circulating within a given community may be considered relatively comparative to the amount of human activity in this period, may remain within the comparative ration until unusual activity such as industrial expansion or disease bearing animals not familiar with an environment and ecosystem interferes, then there is event horizon.
From the levels of the DNA philosophy and the ordering knowledge of the Sciences available to us today, there is no question that it is a mistake to view without reason or even without books, that a certain virus could possibly exist somewhere in the Universe that do not have the basic DNA familiar to mammals, that do not have a basic structure that can be understood and tampered it, and can be used in experimental isolation of several key minerals in the body or in the body of the animals which they came from.
For instance, a Histone and Histamines are minerals based Enzymes that can be extracted from Birds and Calf as well. Histones are found in the Calf Thymus and in Spleen and Liver of bovine mammals, but in all, they can also be found in the Spermatozoa of these Bovine creatures.
Between the Thymus of Calf and its Spermatozoa is one product that are found the in the mucosa intestine, will not propelled a connection between Thymus and Spermatozoa, ready-make the answer the secret of mammalian existence in the final product or Spermatozoa. We seem common that a different exist between the HIV and HLTV viruses given the structure of their heads in the aspects of the protein that enucleate these viruses. The helical difference between these two viruses and the part of the wine…
That the human body, by some means manages to regulate itself through signals towards the release of enzymes, which from the Age of his writing and even now, leans towards digestive system. The connection of poor performance of the Pancreatic juice is not unrelated to Insulin, which he created to have argued as responsible for ‘diabetes mellitus’ or cancer of the insulin.
A measure of his theories about the body and its regulating ability is in the of Science known to more concerned to the role of Chromosome 5, the Chromosome that enables that body to regulate itself through the adaptive mechanism of the nasal which connects to the ear membranes where the major sources of Cold Air for instance are usually passed from the external to the internal.
The explicit role of the ‘Histamine and the Tubermo Nucleus’ (Myron Scholes) in managing the brain (hypothalamus) reaction to temperature towards the release of enzymes in the body, has been extended to the areas of Alzheimer and Schizophrenia, with view that the changes that take in human brain may be due to internal factors other diseases which was initially argued as hereditary.
The aspect of histamine and the association of histamine to fever and influenza (flu) now elaborates on the works of Bernard but clarifies the role of the RNA proteins in exchange of information between the brain the current temperature of human body, that it is entirely possible to catch cold from freezing largely due to the body’s ability to relay as much information through the hypothalamus towards a defense system which can be altered even without foreign elements.
There are chances that the bi-product of the human bodies which are physical and which separate us from each other, can be traced to the last returning few months. How the body carry viruses and bacteria that the body pushing out.
In practice, the total amount of virus and disease that can exit the body or at least circulate within a given community may be considered relatively comparable to the amount of human activity in this period, it may remain within the comparative ration until unusual activity such as industrial expansion or disease bearing animals not familiar with an environment and ecosystem interferes, then there is event horizon.
From the levels of the DNA philosophy and the ordering knowledge of the Sciences available to us today, there is no question that it is a mistake to view without reason or even without books, that a certain virus could possibly exist somewhere in the Universe that do not have the basic DNA familiar to mammals, that do not have a basic structure that can be understood and tampered it, and can be used in experimental isolation of several key minerals in the body or in the body of the animals which they came from.
For instance, a Histone and Histamines are minerals based Enzymes that can be extracted from Birds and Calf as well. Histones are found in the Calf Thymus and in Spleen and Liver of bovine mammals, but in all, they can also be found in the Spermatozoa of these Bovine creatures.
Between the Thymus of Calf and its Spermatozoa is one product that are found the in the mucosa intestine, will not propelled a connection between Thymus and Spermatozoa, ready-make the answer the secret of mammalian existence in the final product or Spermatozoa. We seem common that a different exist between the HIV and HLTV viruses given the structure of their heads in the aspects of the protein that enucleate these viruses. The helical difference between these two viruses and the part of the wine…
That the human body, by some means manages to regulate itself through signals towards the release of enzymes, which from the Age of his writing and even now, leans towards digestive system. The connection of poor performance of the Pancreatic juice is not unrelated to Insulin, which he created to have argued as responsible for ‘diabetes mellitus’ or cancer of the insulin.
A measure of his theories about the body and its regulating ability is in the of Science known to more concerned to the role of Chromosome 5, the Chromosome that enables that body to regulate itself through the adaptive mechanism of the nasal which connects to the ear membranes where the major sources of Cold Air for instance are usually passed from the external to the internal.
The explicit role of the ‘Histamine and the Tubermo Nucleus’ (Myron Scholes) in managing the brain (hypothalamus) reaction to temperature towards the release of enzymes in the body, has been extended to the areas of Alzheimer and Schizophrenia, with view that the changes that take in human brain may be due to internal factors other diseases which was initially argued as hereditary.
The aspect of histamine and the association of histamine to fever and influenza (flu) now elaborates on the works of Bernard but clarifies the role of the RNA proteins in exchange of information between the brain the current temperature of human body, that it is entirely possible to catch cold from freezing largely due to the body’s ability to relay as much information through the hypothalamus towards a defense system which can be altered even without foreign elements.
We may suggest that the chain of discretion between Robert Gallo and Luc Montaigner survives differently, that for instance it survives in similar work of some of the latter day scientist, especially in HIV emphasis and Zaire strain of Chimpanzee.
Following the footsteps of Robert Gallo and perhaps an effective scientist on his own right is Jaap Goudsmit, who like Frederick Sanger, developed major interest in the biology in ways that were not exactly placed on perspective, particularly in HIV studies where he is considered one of the foremost authority on HIV, Beatrice Hahn, Myron Scholes, Michael Gothlieb, Michael Popovic, Jay Levy being among the notable names, of course Myron Essex of Harvard School of Medicine and Myron Scholes of North Carolina could be added, but these are primary list, associated with specific invective and are schools on their own including David Baltimore.
In Guadsmit (1997) we try our faith on the virus in the context of the life-strain which has been in the possession of Gallo, for all intent of academic reasons, there is a mention that a familiar kind of strain used in navigating the earliest promises of the viruses, and his book, ‘Nature of AIDSD’ is a 1976 “isolate of (strain HZ321) is our earliest actual of HIV, since no virus has yet been recovered from the Norway sailor” and this isolate was comparable to the Zairian HIV – IA isolate and seem to be comparable to HTLV – I and Human T-cell lymphoma and Leukemia viruses,* and “Also known as lymphotropic viruses, these retroviruses are not lentiviruses but oncoviruses. They seldom cause disease or meet HIV in the same cell but are prospective HIV partners for production of recombinants. In monkeys they are STLV – I and II.”
But according to Deusberg (2003), in 1985; Gallo changed the name in 1985….for the human T-cell leukemia virus – substituted it for human T-cell lymphotropic virus meaning infecting T-cells, that “A sample of the leukemic T-cells, originally named HUT78, was sent to his lab for isolating leukemia virus.” But Deusberg did not specify the strain of virus that Gallo took, whether it was the one from Zaire or some district in Africa.
That they dovetail the leukemia causing cancer virus in Cancer, means to add that their prognosis of the Feline oncogenic virus – (virus cancer primary concerned with Cats and particularly through breathing) is prove that the Elly Lilly and Rockefeller Institute were familiar with the ‘…cases of ‘Feline AIDS” (FAIDS), which are Deusberg mention was isolated as “simian immunodeficiency virus” and blamed it for “AIDS” in monkeys (SAIDS), all of which are product of the 40’s in U.S and in France, and then 50’s were the curtain gradually fell for the rest of the biological scientist.
There other foundations of Biology and medicine that are important, used in part by Peter Deusberg in his arguments against Gallo and Montagnier that viruses capable of causing epidemic should be new viruses – set in order of Koch – where the theory was also placed in different in terms of (Farr) on the veracity of a New Virus capable of creating epidemic.
In short summary HIV could did not meet the criteria for a new virus since it was always in the system and in fact no new epidemic could arrive human being through new and direct process since all life from a nearest beginning is part of some evolutionary pathway and therefore not new, that new cold cases which arrive either by day or by night in human to human environment, were not new viral cases deserving of a new category such as a case of HIV or immune deficiency virus, which Peter Deusberg argued was not a new cold virus and does not need doctors to defend it, that it was simply not previously diagnosed.
This situation of great importance given the issue of detecting a new virus and its pathology, for if we agree with Deusberg, Koch, Farr, that there are viruses out there that has not made contact with us, that these viruses are not new viruses and therefore not different from the cold, we may consider disabusing our emphasis on detection and mainly detection whose purpose is well served to the evolutionary path or pathology of the very virus.
What Deusberg argues for can mainly be understood from other elements of immune deficiency syndrome, that the cold cases of drug induced autoimmune deficiency were as rampart as the drug and cocktail induced 60’s as they were in 80’s. We betray some of the perceived argument from Deusberg by stating that there elements of disagreement in his book set against Luc Montaigner, that attempt to place emphasis on the redoubtable origins of the Virus – HIV – suffer a consequence given the more mature arguments which could have emerged from his book.
One of the perceived argument is role of evolutionary pathway of the Virus – that given the lack new definition and misdiagnosis of HIV or any virus, there are other reasons why it could have surfaced in specific periods on human existence – for instance during high period of human activity, air pollution, and zoonotic episodes on man and the primates.
In addition to these periods are cases of human activity, that drugs can weaken human immune system, for instance Cortison as demonstrated by many experts and in very recent case by Abraham Verghese, where the introduction of Cortison shots to the body of Rat can give the rat some induced metabolic process especially in case of the rat’s activity that the Cortison shot end up damaging the immune system of the Rat leading to specific cold spells detrimental from blood.
Dr O.U Orji in Nigeria have also found the use of Cortison to have undiluted effects on human blood, the cause of this is not exactly well known, but we can be sure, that the blood structure – especially Hemeglobin is affected by the presence of certain chemicals – such as Cortison (steroids) – which the body need since it widen the protein gates of the body and induces rapid chemical and enzymic reaction leading to increased body activity and blood flow but it ends, altering the structure of sugar complex and nucleotide phosphates for instance Thymus, which is the weakest link in the DNA bases plate.
Apparently all connection necessary for generating new life and possibly creating one adapts to the thymus, which is the very important in production of CD4 and human immune system – and cortison – no less steroid or in many ways than one, testosterone builds as well weak the human elective immune system – especially the male. Taken differently, drugs and drug induced energy products including for instance Gensing is considered a blood thinner for reasons of its reserved ability to delay the oxidation process and the role of sugar necessary to stay oxygen in the blood since the body because of valium do not retain oxygen for long hence we are tired for reasons of life.
Blood damage can occur naturally and like cancer can occur due to genes borrowed from parents, but in terms of artificial breakdown of the human blood and the defense mechanism, it is prolong exposure of the body to damages of all types that induce poor repair strategy for thymus leading to weak and vulnerable immune system no different from HIV.
While we may indicate that the whole statement raised by these experts are true, they are true to the extent that the body could easily adjust to changes in the body and in the environment if and when the exposure to the system does no prove fatal. It is taken that these viruses capable of destroying the body in slow or speed motive are doing so for many reasons including that the body and CD4 cannot keep up.
However there is no going that HIV is an infectious disease in keeping to Deusberg and in Order of Farrs - HIV viruses do not meet the criteria for infection, adding that the virus is considered a retrovirus essentially to the careers of Gallo, Baltimore, and Montaigne, whereas retrovirus and the reverse transcription of RNA to DNA and DNA to RNA though an enzyme, means that HIV could have been the reasons for AIDS as according to Deusberg, but in all, shows that the total damage that the body can sustain is sufficient to satisfy its healing and its cure so long the exposure does not directly and indirectly kill the system composed mainly of active cells. But he is wrong about the dual undeserving dual purpose of HIV, for it to be considered a fallacy; there is something about the changes in human body that accompanies the changes in one’s genetic component.
I shall doubt that HIV lead to AIDS under all circumstances, that some are by nature predisposed to autoimmune diseases and have problem of weak immune system making vulnerable to serious and challenging which like cases such as HIV in stages from virions suffer the victim to ends as end becomes those with compromised immune system open to extreme cold.
In comparative analysis on all that is well discussed and well-rehearsed about human immune system, it is not HIV a virus and study by itself that kills the victim, it is the weakness of the immune system resulting from weak and depraved blood structure and oxygen – cortisone and thymus – that leads to leads to the premature break-up of A helical structure of the blood (Hemoglobin) which is well studied by Linus Pauling and Max Delbruik, Salvatore, leading to the crystalized structure of human DNA and body, and the intellectual history show how the body link the chemicals together in what they call Chemical Bonding and the DNA dogma defined by Watson and Crick in 1953.
David Suzuki and Peter Knudtson… studies in metabolic deficiencies such as Lesch-Nyhan me….Amniocentesis – performed during 14th and 16th weeks of pregnancy, the presence for example, “…the red blood cells of people born with a hereditary illness called glucose-6-phosphate dehydrogenase (6-6-PD) deficiency – a disproportionate number of whom happen to be members of racial or ethnic minorities – are thought to be more susceptible to damage from oxygen depletion during prolonged exposure to naphthalene and other industrial chemicals than are the red blood cells of other people.”
The gene therapy for sickle-cell anemia would involve inserting copies of the desired DNA sequence into ‘living bone marrow cells’ in other to perform a desired function…and the basic steps for gene therapy which is has a lot of promising career is that it helps to welter down the sudden presence of oncogene in the blood and the blood cells. It is through the amplified focus of gene and blood padding, which gives the body a kind of immune defense without necessarily resorting to the body and the cells in the system to fight the onset of HIV and its attempt at penetrating the cells from where it begins to immortalize.
One of the instruments applied is the knowledge application of the knowledge that a single gene resident in Red Blood cells (Hemoglobin) was responsible for sickle anemia. This argument was made especially clear Linus Pauling and his group of scientists, does not differ from the role of genes leading to the damage of an enzyme in the body, which Joshua Lederberg made very clear.
This gene therapy therefore makes its seem obvious that the comparative association of the gene replacement in direct auto-immune cases such anemia and sickle cells, can be applied to HIV since the breakdown of the body begins from the attachment of the Virus to the human immune system.
Without the defense system that circulates the surface of the cells, there is a possibility that the body could withstand HIV or similar virus except that the condition which is not far from the Hemophiliac, could essentially suffocate the virions which entered the body. Although the rapid cells division of the Virus suggests it may be not be possible, it is however reasonable that the earlier a victim begins a treatment the better. Gene therapy is not sufficient enough in nestling the problem of HIV.
Heterozygous sickle cell traits from both partners may warrant their children stand 25% chance of having homozygous sickle cell anemia would involve inserting copies….the desired DNA. Bone marrow cells are the source of a patient’s genetically defective red blood cells…..“….cancerous blood-forming cells in a patient suffering from Leukemia, for example, are replaced with cells from a healthy, tissue matched donor….”Gene therapy for sickle-cell anemia would involve inserting copies….the desired DNA sequences into ‘living bone marrow cells’ in other to perform a desired function…..
The basic steps in gene Therapy for sickle cell Anemia…..
Oncogene sudden change…
Vulnerable to untimely collapse each time blood oxygen levels decrease….The genetic Basis of sickle-cell Anemia, it affects the production of one genetic pool for identical normal hemoglobin, sickle cells – and low (blood) red blood cells…
Linus Pauling – and his group demonstrated a ‘single molecule’ defect resident in Red Blood cells hemoglobin was responsible for sickle-cell anemia. To demonstrate this as they placed Hemoglobin proteins in a gelatinous substance and exposing it to weak electrical current (electrophoresis) which demonstrates the chemically based difference between two separated. What they also discovered is that when the valine which is an Amino acid is turned off with glutamic acid, it directly alters the shape of the hemoglobin which is usually three dimensional given the arrangement of the Amino Acid.
When the mutant S hemoglobin (Red Blood cells) encounters low oxygen blood concentration, the hemoglobin becomes erratic in a bid to form its own crystal structure and ends forming a structure that is quite different from the three dimensional regular Amino Acid. The result is that the structure based loosely on a fractured composition causes the cells to collapse. In essence the sickle cell after a while is returns or re-encounters an oxygen rich part of the cells and circulatory system, these formative molecules break-up, which is on contact with oxygen-rich blood, allowing the red blood to return to its regular shape…
One of the more contentious of this period which lends itself to Enders in some level, it is the charismatic clarity of Chemical bonding at the level of human blood and hemoglobin and how the permeation of Sickle Cells and other blood cancers were undeserved death sentences.
Where certain chemicals can induce the worst human reactions, that they can damage the crystal structure of any blood leading to premature explosion of the walls, it is well studied that the real reasons behind the poor regulation of the oxygen in the blood or in some cases, poor regulation of sugar in the blood resulting to a different pancreatic cancer called Diabetes, Sickle cells enfeebles the victim by squeezing the consumption of rate and hence the duplicity of red blood cells in the human body, whose primary role as a b complex is to condition the profligate activity of the white blood cells primary thymus depended.
You are no longer in control of your senses when the red blood count decreases and panic and headache no less different from advanced types of diabetes send the patient various ends of pain and aneurysm and the body demands its shots. It is the lacks of red bloods and high dose of white cells that signals the beginning of the age of new infection in the body.
These are side effects which medicine over the course of the last 30 years has helped to undress but the main events of the HIV is what happen to the blood and the rest of body – especially the spleen which a personal theory – leads away from the old into the new and back to the old that the HIV is a virus that induce various forms of blood cancer, that it means the body progressively vulnerable to invasion, that we thin out due to the role of the virus and we die gradually and grudgingly from AIDS since the body is no longer at ease with blood stimulus – hence poor production of red blood cells……..
That in limelight of those who discovered the oncogene viruses or isolated it from the strain of a cancer causing virus, it was achieved in 1951 at Rockefeller Institute from possibly a strain of the Congo virus. It means that the dives on Gallo’s HIV buffs, is probably not new, may started as a trial in the context of the theories about Viruses and primitive parts of Africa.
If we are to break it down, it almost seem to point out the that strain of Gallo’s virus that was available for processing and was available for early consumptive laboratory work was from a strain of the virus from Zaire, that it may have a common physiology with the strain of those of the Norwegian sailor, even in his estimate the man was no longer available.
Sampson I.M Onwuka
The Chapter was destined to be written and the final solution begins from where we started….
There is something about the Medical Institutions and the Act of medical discoveries that can plunge an entire world of information into some abyss until perhaps redemption. All the breakthroughs in science and technology need not be rehearsed as a consequence of these long years of experiment and studies, leading to disasters of all types and sometimes with some degree of consequence. One man whose theory concerning the problems of perpetual error and why institutions carry on with these mistakes is Joseph Greenberg in his dissertations about language and human dispersion theory, theories well evident by the Luigi Cavalli-Sforza. Mistakes can be conceived by any number of institutions and can be transferred from one form to another and until a breakthrough; it survives some of the assumptions in business and elsewhere. The advent of HIV at least in the least in the last 35 years is no different from this kind of problem, especially those of Polio which has given us all the headache known to us.
That a thing and perhaps a sickness such as paralyses from Polio eluded the frontiers of sciences for at least 40 years in spite of the breakthrough by the Karl Landsteiner on A, B, O on the bone marrow and the brilliance of a certain Jewish immigrant by name Simon Flexner who for his sake and for the need of medical research that they developed the Rockefeller Institute in New York. These men including those took umbrage under his leadership, (1) Herald Cox (2) Max Theiler (3) Isabel Morgan (4) Thomas Francis (5) Tom Rivers (6) Peter Olitsky (7) Albert Sabin, names very familiar with us in Virology and the culture, and like in many open sources these are champions of medicine for many years in vaccination and early attempts stem cell research. The book that throws some light on the history of these few including the familiar Max Theiler who succeeded in growing a Virus in the brain of mouse is called Polio; An American Story, by David M. Oshinsky (05), we should be able to quote from this book, at least in gainsaying on some of the assumptions about the connection between Polio and HIV, where the author made some medical blunders no more than the ones that Merck made about the unknown dynamics of the human immune system.
But in Oshinky’s ‘Polio’ story we are privy to his citations describing an important figure in fight of Polio by name Karl Landsteiner that “At his Laboratory in Vienna, Landsteiner produced an emulsion from the Spinal cord of a boy who just died of Polio. He passed the liquid through a porcelain filter, injected the contents into the stomach of two rhesus monkeys, and waited to observe the result. It didn’t take long; the monkeys proved to be wonderfully susceptible hosts. Both succumbed to Polio, their spinal cords showing much the same damage that had occurred in the little boy. The Polio virus had been isolated.” The process of extracting a virus would in future be that complicated but they follow the same process, yet the intentions behind rendering the piece in spite of the Polio is taint the discourse with the bone marrow incident regarding the treatment of immune deficiency syndrome that much effort has been put in to help the victims of the AIDS whose bodies are racked by the virus by chemotherapy in removing much of the bloods in the spleen and bone marrow of the affected areas or areas of interest, and using a foreign entity and bone marrow try to restore the blood of the patient in a process that is similar to cancer treatment yet they get worse and worse.
The point that HIV is at least for now a blood borne Virus does not.....
If the virus is fed through the mouth the victim hardly suffers any special injuries and any specific inductive injuries but when the Virus is fed through the nose, the reactions were very fatal. In fact the mode of infection which are so believed as the same and similar to Tuberculosis which infected people through the nose and breathing, cursed severe reaction in the body of the victims particularly the monkeys, may have given some reason that the mode of penetration of the virus was similar to other agents of the body.
David Oshinsky writes that “No one found a way to block poliovirus from entering the body or to neutralize it with drugs or chemicals once it got inside” For many years the conception that the nose was how the virus entered the body proved frustrating to scientist and in the image of Simon Flexner who help to carry out major reforms in virology, there was hardly anyone to challenge the basic assumptions. There was something else, apparently the reason why the mouth feeding of the virus did not convey any particular kind of adaptive meaning, is that the monkey used for these experiment is called Rhesus monkey. Its ability to mount immune response depended on many things, in part for the silaic acids which are contained in the body and are presence in the nose and nasal cavity, exfoliates its existence and as someone theorized, many people did not know why we couldn’t stop the virus from entering the body. It would seem that it was only through the nose that such penetration of the body was possible.
The story on how it was discovered that other primates reacted differently to the virus when fed from the mouth is not clear, but the opposition of Flexner to the use of these primates proved that it was a well-known fact or suspected as such that a particularly kind of monkey acted differently when the virus is fed through the mouth. The rest were victims of the same thing. For that reason, the understanding that the route of the virus was from the alimentary canal and not the nose or at least more than nose, proved a damage to Flexner’s theories and became a point of rally for all scientist. This new knowledge is so critical to further enhance the experiment on Polio viruses that it led many scientists to shift their attention from monkeys to chimpanzees.
Oshinsky put it kindly that “if Polio virus entered through the mouth and worked its way down the digestive tract, then it must travel through the blood before entering the central nervous system. If so, a vaccine designed to raise anti-body levels in the bloodstream would be able to neutralize the virus before serious damage was done.”
From this development, they were able after almost forty years of the studies on Polio virus to now learn how the virus develops and what makes it work and why the virus became a hit for the rest of the scientific America. At least Scientists were now able to focus at (early infection) and the blood stream was the place. In the words of John Paul, “It meant that small amount of virus which invaded the blood could probably be overcome by relatively small amounts of circulating anti-body, and by this means could be blocked from gaining access to the central nervous system….At one fell swoop, the problem of immunizing man had been rendered easier than was expected.”
Among the first investigators to look at the virus in previous and neglected blood samples was a certain Dorothy Horstmann, who was a member of Yale crack Polio Unit team of invested much of her time in looking at blood of the victims that came into the hospital from the 1943. A basic line should include David Bodian and his group; she was not the first or the only one that looked at the blood of the victims that were infected by the Polio virus. And the blood became very central to the point of demonstrating from the stored blood of nine year old, that unless the virus was not in the system and in the body already, there was no way of knowing unless she got sick. That it was only on this account did any change take place in the body at all, that as soon the blood realized that it had a disruption in its system, proteins and folded inwards and then the attack on the nervous system which is primary to the virus.
If fed through the mouth the virus could invade all the stomach and reach down the body where it profligates, but majority of time and according to several practices which are done, the virus hardly makes it into the blood stream in large amount when induced through the mouth of some monkeys and ended up creating paralyses leaving antibodies which has neutralized the virus.
The whooping size of his academics raised the tempo of suspicion towards Apes, Chimpanzees, and Monkeys as probable origins of the Virus which eventually came in with their mutations in human and hence nearly justified the all kinds of experiments in Congo. I must confess I have only casually flip through the books and do not intend on writing on what clearly obvious from his missive that the general academic consensus favors a Spillover from Monkeys and Chimpanzee into Human beings.
Philip Alcabes (2010) Dread book that attempts to consider what the early CDC workers attempted to achieve with HIV and how some of the jokes about HIV did not shy from the social stigma of those who were called freaks or in the 60’s bums, who suffered all kinds of malfunction in the body and were essentially housed elsewhere till perhaps redemption which sometimes arrived too late. If it is not impossible to locate this item elsewhere is because of alternate historical account of outbreaks in City wide location, point to breakthroughs that gave medicine a new and profound meaning.
In his chronicle on HIV he pointed to an early date made by CDC released in September 1982, that “Homosexuals or bi-sexual makes – 75%, intravenous drug abuser with no history of homosexual activity – 13%, Haitians with neither a history of homosexuality or intravenous drug abuse – 6%, persons with hemophilia A with no other risk factors – 0.3%, and persons in none of the other groups – 5%.” Whereas anyone could get the virus he argues, HIV was simply the most dreaded thing partly for the fact that there was no cures at the time, but largely for the social stigma that was associated with it. Many of the Black and Hispanic in New York did not see it as very present and dangerous virus capable of infecting black as well others, and they loathed the virus as a white-man disease.
But before long, it was gradually shown that the virus began as a series of carefully planned conquest over the host immune system, and after a decade of the virus of the human it degenerates into something else.
For if Blacks were gradually gaining up to others despite being one of the smallest groups of minority in New York in terms of new cases on HIV, it was due to the problems of information and reaction, which do not add to anything useful.
For Asians and Africans, they were largely hung over on the transfer of the new virus emanating from Gay Communities in New York to other parts of New York and elsewhere, and since they loathed these communities; they are easily vulnerable to the viruses. Although New York in times past may have entertained the arrival of diseases and other infectious disorder, it has lead the fights against dangerous diseases, against Polio and Influenza, against diseases; both airborne and waterborne. The City is hive of visitors with long term view of the City and travelers for other reasons and immigrant population since the 18th hundred has continued to sprawl till very recent days.
New York downtown has no particular architectural, the immigrant populations; Irish, Italians, Jews, Africans, Caribbean, North and Central America, and other income capable brackets were primarily concerned with their own survival. Although the immigration continued in New York by Europeans, it helped to form some of the assumptions about new diseases and epidemics, to a point that it can be said that studies about the early diseases in New York in the last 100 years or so were mostly derived from reaction to outbreaks such as Chicken Pox (Varicella), Pertussis (Whooping Cough), Pneumococcus, Hepatitis A, Hepatitis B, Rotavirus, Influenza, Meningococcal and some variety of human papillomavirus. In a sense some of the assumptions about these diseases made outsiders temporary targets for reasons of their own.
The Polio virus was one of those outbreaks where a strain from African monkeys was very necessary in understanding the pathology of Polio which Flexner believed was generated from stomach to the body or through digestive tract – in essence it was ingested. Many of the experiments at the very beginning had to with mouth feeding of some of the creatures and primates – especially monkeys were fed through the mouth with strains of Polio virus and the end was not to the interest of the scientist. The main point is not the process of profligate Polio virus but on why it was necessary to ingest the various from the beginning and why the issue of blood pathogen proved a different and difficult point to redress. Look at it differently, when it became very clear that the Polio passed through several processes and especially the blood, the science committee was more than ready to handle the Polio mellitus once and for all.
Secondly, if the mentioned virus-ridden diseases and conditions, especially Influenza and Spanish Flu for instance of the 20th century A.D, were considered from purely medical and biological point of view, they show patterns of infection and host-DNA which alters the destruction of the infection process of the virus, some produce fever others with the same viral infection may give similar but different infection in the body. The immigration population who make it to New York where left to places such as Randall’s Island, New York, a place which as the repository for those dead or dying. Of course they naturally remain quarantined saving for instances of Polio and viral strain of its culture.
The modernity of New York as now and then appears on the world map and its visible schools of medicine was not always the case, for at least we can set our eyes on the formidable FDR days, whose efforts as Governor of New York and eventually president proved a watermark for the attitude of the public to issues of health. It would not mean that Harlem River drive heading the F.D.R was named after for political reasons, but the combating of Polio by forces affiliated with his office such Bob O’Connor makes the faithful date of CDC recent as they provide the necessary tools towards the growth in health we have seen over the years. But needs be mentioned that a lot list of all the breakthroughs of sciences in the United States and in the world did not arrive by idle conjecture, did not arrive by efforts of any one group such those for instance at Rockefeller Institute which has fielded and trained more competent and decisive virologist in the last formidable century, more than nearly all institutions anywhere in the world.
Perhaps the Pasteur Institute of Paris or other Schools of interest in Massachusetts; Harvard, etc., which though perform its function along the elite schools of the country, cannot in itself expel the contribution by other schools either directly or indirectly influenced by Rockefeller Institute in the last century.
This will not mean that schools such as City College of New York with as many Nobel Prize winners as Yale is to be taken away, it shows however that the merit of open culture and attitude to this merit widens on the even the smallest avenue of possibility that what works in one area, may not apply in other cases. It will be useful to point that the Cold Spring Laboratories in Long Island maintained an open culture and relevancy of attitude to science from the days of its founding by Watson and Company to nearly all combating of new virus which CDC is particularly known for. That will add to the assumptions that the failures over the years to deliver on HIV may be due to the fact that it was believed to be disseminated through deviant sexuality and the encouraging the scorn that it was created by God. But if half of what learnt over the years and at least in the opening heroic search for cure at the beginning was never replaced or transferred from one community to another, we may have in my view – purely in my view – put a final end to the Virus.
While it is easy for me to accept that giant steps in Medicine has failed in generating final solutions for HIV, it serves then as well now as an example for what may have transpired between Polio Virus and the arrival of the scientist who ended the whole sage. In areas I succeeded might clearly interest you with the fact that I spent 2 years studying Harvard Medicine for fun of it. And in the last returning decade and a half have spent hours of a given day on History, Anthropology, and generally studies human genetics. Majority of these studies show it’s relativity to HIV and the cure for immune deficiency syndrome prove a lengthy stay for reasons of their own, to a point that some of the conclusion vary in its results and the end point was a question of some understanding about viruses and its evolution. This aspect of our understanding of biology and chemistry is very important given the very reason why vaccinations seem to have failed.
Barely a year ago, the argument about the SVO40 virus supposedly from Chimpanzee and the Polio virus seem to have stagnated between Chimpanzees and human immunogenic viruses, which may have resulted the strain from Polio considered a leading item to HIV. But this argument in all its forms had to be dealt with, perhaps decisively given the basic premise of HIV infections and its pathology. Put it differently, there is no connection between Polio Viruses and HIV, and there is no link between immunogenic viruses which infect primates and humans saving the issues of the patterns of infection and the chief cause of the agents. The example about the slow viruses and oncogenic viruses are especially important largely for leading but misleading line of reason about HIV and the very knowledge of viruses and immune deficiency syndrome.
Looking backwards to some of the stories from Bronx and from parts of White Plains, New York in the early 90’s, there is hardly anyone who knows what the virus was all about and what its problems anywhere. It was known to be deadly, known to remain dormant for a long time, to be conversant with Homosexuals and with illicit drug users, where they speculated that sharing needles was very dangerous because of the dangers of blood contamination. Special classes are taken to handle blood and the secrets keep so tightly about victims that even some of the workers were placed on a need to basis. On a special basis as well, there are reference to Russia and the events of Cold viruses, including period of long epizootic and Moritz Kaposi (Russia) associated with description of what eventually considered Sarcoma, and pox related virus sickness.
It will seem also that the comparison between the Lentivirus that Montagnier is associated with is not unknown to Gallo, promotes only two possibly arguments that Robert Gallo were looking at the comparative physiology of the primates and the humans, their gaps in defense mechanism and whole comparative physiognomy, that he believes in lieu of Rockefeller Institute and their historical breakthroughs, that a similar virus if discovered in the primates can lend a pair of eyes to those of humans.
The second reasons are that he and his group may have believed upfront that the virus essentially came from Africa. It is only reasonably reassuring that Interleukin-2 associated thymus which Montagnier emphasized has its reasons, based perhaps of Claude Jasmine Chermann.
When we look at the structure of the protein from sources totally available to us, the use and eventually the abuse of Gallo’s strain resulting in its isolation of the human version of the Zairian Strain, is said to be oncogenic virus, means that it is cancer causing, will also point to the fact that over the last returning decade of the search for HIV and its cure was sentenced to a goose chase, point must be made that the strain however oncogenic could not connected to human cancer, though the virus when triggered delivers according to its purpose.
Therefore a connection between the cancer virus and human immunodeficiency virus were test that led to wrong conclusions, for if HIV in of itself could infect monkeys, a kind zoonotic trans-infection would be possible among the humans. Looking at the conflict in the early years between Gallo and Montagnier, it is becomes gradually clear that Montagnier or the house on which Montagnier is based would have collapsed, were it not for the fact that he did specifically mention that he used the Interleukin-2 protein induced virus to isolate the HIV virus, suggesting that he was right that the virus called HIV or initially a LAV virus was different from Gallo’s Virus.
For the similarity and differences between Gallo and Montagnier, it will be common sense to show that cancer is the bottom line in whole argument, while the Gallo cancer causing virus is different from Montagnier is perhaps due to their specific origins. Although there are other viruses that trigger the creation of mutants, the rate at which we notice the differences between the two scientists is what their viruses do inside the body. HIV can be called a kind of cancer; perhaps blood cancer given the long held observations of people with the virus and may have been the motivations behind the use of cancer agents with direct reference to the blood.
But it is the blood that matters, what happens to the Red Blood cells over time which ends up affecting white blood cells or CD4 counts over time. A dip in the CD4 counts eventually comprises the body’s defense systems. We are now certain that AIDS patients die from Opportunistic Infection (OI) and not from HIV itself. Looking at the history of HIV from these schools will arm with some basic understanding on why emphasis on thymine very central towards the survival of the patient, and why most efforts in correcting the reverse transcriptase did not perhaps lead to any new grounds.
Here it will be rewarding to show that mycobacteria is not a new name in the market, it is has been and for many scientist for instance Lynn Marguilis and her colleague Dorian Sagan, have given some academic devotion to the transformation that take place in the life of a bacteria and how these mutational changes, from one area of the chromosomal to another adds meaning to what is now called Epigenesist which..., and which Adesinine and Guanine based protein building on a three level phosphorylation within the cell and through diacyglecrol perform separate respiratory function relative to the ions of the surface, where a short and misconceived attraction and relapse duration(cell respiratory on the Golgi body) can affect the false release of information and trigger event reaction from the cell are based on some role of oxygen.
If we recall briefly the experiments of Oswald Avery on pneumococcus, there is an express that he defined about Deoxyribonase Nucleic Acid (deoxyribonucleic acid) there he emphasized thymine as operand towards the creation of new DNA.
some multi-celled organism living in the gut of say Cow or in its intestines, which are naturally used for the reproductive processes of a milk (bi-product) are not normally known to be destructive, may remain friendly in the gut and intestines of the Cow or other mammals until the frequency of the cells or immunogenic is comprised….It is these two viruses that are equally significant in the defenses and failures for and against HLTV virus which are generally oncogenic such as the ras and abl and to some arguable degree yes genes in blood and pneumonia related cases can be represented as viruses received from several range from bare-back viruses such as mycobacterium, particularly Avian which is a Sars virus which is respiratory based virus and in like viruses or multi-cellular organism and their viruses….
Flossie Wang-Staal researched with great success of the structure of HIV, and it was the knowledge of the transcription factors acting on the HIV, especially in the introns and enhancers, the terminations point of the Amino sequencing that provided the base-board for developing AZT, which implies the phosphate roles of thymine and was set then without knowing against a alu genes. The marking in terms of the transcription factor largely because HIV is replicated at the right of the LTR, but seem by its transcriptase to have perhaps started its origins at the left of LTR.
That it is no use and cannot really affect humans as such the placement of the virus at whatever angle and its conjugation to the nearest human cell which replicates at the right of LTR as with Amino Acid, prove to be well meaning for a healthy life of a cell, but this key location could also transduce a mutation leading to cancerous edifies or creation of mutants. This in-of itself can induce cancer causing deficiency in human beings and has means and ways of expressing itself in human beings as primates – with or without due respect to the Alu genes.
For all intended reasons we presuppose the methyl alu genes is a jumping genes that is not insubordinate to mutations, and should be classified as mutagenic. Alu genes are relatively twisted does not mean they are retrovirus or retrograde, but there are reasons why these twist, they reveal a different version of the genetic DNA especially among Africa Blacks. It is suggested that this is part of their evolutionary past is prove to the causal link between the past Great Apes and the present but these are alu are not formed in the Great Apes and not prions or dangerous....
The man who whose theory on defective proteins and prions, whose work transformed our knowledge of prions is Stanley Prusiner. Whether the constipation of the alu genes or the jumping genes that confirms Stanley Prusiner (U.S) long lived Noble Prize on Prions as infectious proteins, we are clear that infectious proteins are mutagenic and does not inspire a transformation from one form to another, a saturated argument anyone can make saving for the vast implications in phage studies.
For sure if in more recent times, that Arjit Varik and Elaine Muchmore in trying to adapt a new drug to enzymes working to oppress the profligate of HIV did not award much help, there is then something wrong in the process, a misleading grasps of the fundamentals of molecular biology or in recent times, RNA sciences. “By 1998 Varki knew why we were peculiar; a 92-letter sequence was missing from a gene called CMAH on Chromosome 6 in human beings, a gene that codes for the enzyme that makes GC.” ‘Right in the middle of the sequence was an Alu genes = ‘Jumping genes. “So sometime after the divergence of the human and chimp lineage, this Alu had done what it does best, which is to jump into the CMAH gene, swap places with the older Alu, and accidently remove the 92-letter chunk of the gene while it was about it”
‘Throwing stitches’ using his exert quotations, Matt Ridley stated that the “Hox genes are the recipes for proteins called “transcription factors”, which means that their job is to “switch on” other genes. A transcription factor works by attaching itself to a region of DNA called a ‘promoter’, where IGF2R gene on Chromosome 6 ‘Premature damage to the brain or late development…
AZT as described by many experts is cell mediated immune response where AZT is incorporated into the host cells, DNA, and as Irwin Sherman suggested it is shown to be introduced in some numbers in the DNA which is set to clarify what Peter Deusberg mentioned that it actually tampers with your human DNA, whereas the Factor VIII mentioned by Deusberg is not exactly anomalous may prove to be relevant to Hemophiliacs…..
On AZT a ground breaking theory, we have noticed the work of other experts such as M. D Grmek (1990; translated by Russell Maulitz, Jacalyn Duffin), that points out the evolution of the disease in six hierarchical stages and according to the maturation of its protein, which for the author reflected “the chorological and biological status of infection…” and it is A, T, G, and C, that make up DNA…..3-azido-3’-deoxythymidine – or AZT…., the Antigen-presenting cells and whose Human leukocytes, Storm trooper T cells antigen (HLA), Viral antigen, T-cell receptor (TCR) and in one major combination shift from basic complex to defense mechanism – more like the age of protein, with age protein perform different function in human body.
Dani Bolognesi, the whole structure of HIV protein fell, with one particular emphasis of the gp120 envelope glycoprotein. This gp 120 proved a deciding mark in the renewed assault on HIV sometime in 80’s and it revealed considerable presence of what he called ‘main proteins’ (P24/25 inside of the protein box, and gp120 and gp41-43 outside) whereas some of the proteins are well to share comparative similarity with sooty mangab1ey (cercocebus atys) which carried a strain of the virus (STLV – IIIsmm) inside.
In relation to these strain of viruses, there are lengthy….Grmek as one the foundation members of the war against HIV mentioned understanding the cleavage enzyme that was delayed in the orchestration of the CD4, and the primary.
Daniel Bolognesi continued that ‘To this end, biological modifiers of the T-lymphocytes, such as interleukin-2(IL-2), hormones derived from the thymus gland, or thymomimetic drugs (DTC, commercial name imnthiol), were tried, as well as transfusion of HLA-matched lymphocytes or even bone marrow transplantation.” Emphasis – even after some decades on HIV is thymomimetic drugs which sometimes prove poisonous given its
“The first of these products autoimoniotung state or HPA – 23 (so named because it was the twenty – third heteropolyanion synthesized by chemist Gilbert Herve and Andre’ Teze), was known ever since 1974 work of Claude Jasmine Chermann as an inhibitor of reverse transcriptase in the retrovirus responsible for murine leukemia and sarcoma. Chermann studied its action on the AIDS virus. HPA -23 inhibited the activity of LAV reverse transcriptase in vitro.” And for this breakthrough studying the reverse transcriptase is greatly advanced, has dominated a lot of studies in this respect excluding gene therapy in very recent terms.
The impact of HPA 23 in reversing elemental LTR Amino replication center including the P. 53 for cancer with respect of the age of the cells (telomeres) never papered as accurately as the promise of reversing the reverse transcriptase of probably trapped bacteria prophage in the evolving chromosomal based (HIV) Viral RNA. The understanding that genes sometimes trip the activity of Amino acids is a well-established and grounded biological induction, especially manifest in the attempt of showing the physical-chemical properties of cells and their lopes which on the surface are controlled by the transport of energy information and by default oxygen.
Although the uracil (urea) is the set aside as the element that it responsible for the beginning of the process of all biosynthesis with look-alike bases comparable to phosphate-methyl 5, most common of which is thymine, it is for this that elements containing uracil with the 5th position as bromo-uracil usually translate in the second stages of the sugar complexes wrong information, since the mutant protein or bacteria that break them the coupling polysaccharide is turned off or at least considered mutant, and therefore cannot profligate at the essence of enzymes that dissolves sugar complexes.
This alone along with activities that result from the excess lysogenic activity does affect the replication of Amino Acids, may help in editing some of the information between RNA and DNA, may repay false RNA to RNA, but may not probably trip the genetic activity resulting from the rest of body but eventually affecting HPA 23. In essence, this attempt by Chermann to inhibit the profligate of the VIRUS through arresting the activity of the binding reverse transcriptase, may involve the artificial introduction of thymine – which essentially aids the cells to control the activity of dictated foreign antigen.
Michael Bishop and Harold Varmus discovered that “virus-encoded oncogenes originate in eukaryotic cells.” But it will be the Gallo team that will make the better of this theory, and if in the decision which lend meaning to how some of the theories of oncogenes that dominated the early and later stages of Baltimore is placed on the same context as Gallo as he presented some of his assumptions.
That “The HIV dissidents could see two fundamental problems; HIV was a retrovirus, meaning it should not kill the cells it infected, and the virus could barely be detected even in late-stage AIDS patients”, Deusberg (2003) which threw its own light in the context of well understood realities of the Virus and why it remains part of the human body in spite of the drugs released to deal with it…..
Although Deusberg and company need to place some faith in the assumptions raised by the two leading schools of Gallo and Montagnier, the later holds more promise but Gallo may have struck an ideal comparative between the operational dynamics of a leukemia virus – perhaps in the discipleship of Stanley …..and his prions which are destructive proteins which also have origins somewhere else, and still for reasons not exactly clear is short of the right stuff in fishing the left and right of HIV when the CCR5 is knocked out in experimental relocations of the…..
In the event that some worrying castigations on the number of failed vaccines – at least well-meaning 20 vaccines - can be left to the primitive carousal of a CD4 protein inhibitor by name nef so named by the company that identified the proteins which HIV DNA based do not produce, it may not escape our mind that the intrepid connection between the SV…..In one Deusberg’s exertion’s “AIDS is not a disease. Instead, the AIDS Syndrome is a steadily growing collection of (currently) about thirty “previously known” (old) diseases.
Surprisingly in view of their notoriety for AIDS definitions, It is true, however, that the incidence of AIDS diseases has increased dramatically in the 1980’s as intravenous drug use has increased and as both the consumption of recreational drugs used as sexual stimulants and the use of AZT as antiviral drug have increased in male homosexuals….”, may true to a large possible extent, that the problem of HIV viruses, as they apply to Deusberg theories, is not necessarily the lipid bi-layer of its outer shell which duck the human cells containing CCR5 receptor, which also promotes the second attachment between the Virus and the ducking CCR5 from the HIV virus.
Leads to some conclusion that emphasis on the viruses on the context of its ducking technique is only correct by some extent alone. That the problem of the Virus is not with outer most cells, it is with core-protein of two split Streptococcus placed some arrest by some CD4 who origin can be buttressed by the core-protein of HIV protein structure, showing that it is operation at a DNA viral level, would not naturally mature into adult Streptococcus, that is splits ends RNA+ virus whose primary existence is the B> bursar cells that is similar in composition Amino Acid from more older cell wall controlled and depended interactive from and mononucleosis as presorted in Cytoplasm during meiosis, that it farcically relocated in the human cells which re-dominates the virus, controls but does not effective destroy it. It looks that the Streptococcus is one the few capable viruses inside a human cell that profligate by relative contrast between the Amino Cells,
David Suzuki and Peter Knudtson on G-6-Pd and job related anemia point to histone and the expression of Chromosomes. That “For example, a disproportionate number of sperm cells of male workers exposed to an individual chemical called 1, 2 – dibromo-3-chloropropane (DBCP), known to cause sterility in men, have an extra Y chromosome resulting from nondisjunction during meiosis…”
Y chromosomes are not easily digested would look the part of interpreting the dysfunction of a mutant protein as similar in composition to the Y sperms reintroduced into the body. It is not exact the case but the extent that somewhere in the ‘code-script’ used crudely by Schrodinger in showing that the full structure of human body are products of a system that essentially repeats on its scripts or forms, that over time, the smallest conspicuous elements retaining these code-scripts or what we call DNA, essentially give rise to a super structure. It is true that the smallest pieces of human body may retain the DNA that provides its own history. But there is a different between a DNA and RNA in such category as that we relate the ability of a bacteria or multi-celled organism to retain its DNA is based in large part on its ability to retain its Chromosomes in the body of its host.
There are several blood types and measures in medical sciences that require the transplantation of one body to another, for instance the transfer of lungs from one body form to another, requires correlation to blood types to the extent that one’s immunology can react to the plasma used during transplantation. But this relative reaction of the body to new substances leading to Cancer and auto-immune reaction do not in reality affect the body’s DNA composition.
The same cannot be sued of the bacteria or a multi-celled organism or in some case Viruses. Bacteria can affect our Chromosomal inheritance by being parceled to the next generation following its injury to the gene. To the point that a genetic material passed from the parents to offspring may have resulted from an injury inflicted on it by the latency of some organism. In reality, there is possibilities of replacement of the affected or damages genes after mitosis when there are more than a spare of healthy genetic pool, but some combination between the two parents does not have any spare to replace it and the damage to genes is carried over to the next generation. It is not also what blood can deliver, some of the blood treatment are realized means of temporarily healing the body, some blood transfusion – the best blood ; the high density – are used for temporary treatment and are eventually replaced by reproductive ability of the host body.
As such a continued injection of blood for some sickle celled, or those with familiar and unfamiliar blood conditions, may only temporarily offer relief of such conditions to any race or to an individual. In the end, the host reproduces its own blood and means. Arbitrary means such as Iron based immunogenic (which helps to manage the transportation of oxygen in the blood, necessary for prolonging the life of HIV patient due in part to the diminishing thymine or T-cells whose roles are intertwined with interleukin separate from Glycerin (visna) and Serine (bovine) lentiviruses, all of which result a diminishing of blood sugar; galactatosade base, lactose, and improper release of oxygen leading to collapse of cells walls hence a deficiency of oxygen bearing hemoglobin and an onset of auto-immune failure from a faulty and pre-packaged three-dimensional Red blood Cells which drives the body’s reproductive and immune based ability, whose profligate ensures the survival of the plasma; the engine of life) and sugar based complexes (enzymes) such as Insulin, are temporary but like temporary relief such as AZT for diagnosed HIV conditions, may temporarily faux with the DNA of the host and when overdose may prove toxic to the body.
We consider that instance some families with long list of genetic diseases, may carry this genes from one generation to another if they continue to propagate their offspring along same and similar genetic pool. It is with marriage from outside a lineage can they body biologically alter the inheritance. It all probability, there is nothing to ensure that a survival is constant than the attempt to expand the genetic pool of the reproductive organ. To some extent, we may consider that biological conditions are derived from lack of fresh genetic pooling, to the point that many African Americans for instance marrying outside their race may attract a lower and lighter density genes, which may not support their natural sugar production.
Plainly speaking, there is a great problem of diabetes largely from off and on interaction between their high density genes and lower density genes, and when there are obvious cases of high artificial and starch consumption. However, a continued emphasis on a small genetic pool or say lineage who have reached maximum propagation of genetic material leading of a reform of color bases and yellowish appetizing from dermis countering epidermis, may force some of the gene pool from its bearers to retain its damages due to lack of alternate replacement – for instance sickle cell among a variety of the blacks and particular among Africans (Igbos, Bini, Ethiopians, Egyptians, Cameroonians, etc) – may be transferred to a new generation without problems.
But majority of these sickle-cells problems with die a natural death should these group or family with such history marry a few degrees from their core. African tribe such as Igbo to African tribe Yoruba is an excellence example. For some changes in life to become permanent, it is biological science that it should passage through reproductive processes. Does not mean that it applies to all proteins and enzymes especially when they appear as a side-effect from a disease bearing bacteria or virus. For us to place some hope on why the male is perhaps responsible for the birth of the new virus, a more difficult but somewhat intelligible assertion using the operon in E. Coli experiments mastered over 40 years by the America phage group beginning with Luria and Delbruck but essentially clarified in the long experiments of Monod, that between the repressor bacteria and operon, it’s the transfer of material information from one bacteria male E.Coli to a female E.Coli, whereas the reducer (needing less oxygen; the female) is the one that carries on the replication.
From this easy angle, a cheap interpretation is wholly important is that seems that the discoveries of Stahl and Messelsn’s of the impossibility of Phosphate sugar without oxygen, seem to play that the male bacteria used oxygen its resolution of sugar complexes and in the process enable to consummate on the female. All properties regarding this transfer of material benefit results on a seeming and possible ending of a process, yet it does not mean that the male bacteria dies, it means that oxygen not unlike the processes involved in addition or removal of oxygen in human bio-synthesis by the ribose Sugar (Deoxy-ribose) is grounds enough for new DNA replication. But it is close since the only process a bacteria can make a DNA is through the reproductive processes trapping and using oxygen and through the use of a thymine based element and probably uracil.
The ability of the body to compensate on this F-factor by the sitting or ducking bacteria is due to the host’s or cell’s ability to regulate the profligate activity of the RNA. It is here all too clear, that majority of the disease based immortalized cells which are able to reproduce on their own, began with the F-factor processes, that it needs be said that replication is female as the inception in complete and profligate which occasional leads to high propensity, to a false attachment and re-awakening of the dormant viruses and bacteria is to some extent male–ridden and may regarded as RNA+. All viruses and bacteria capable of infecting the body are usually RNA+, due in most cases on the truancy of a foreign cell which finds mating capacity in the body of the host and its B-cells (bursar) and which penetrates the cell of the host by ducking its surface using the glycol-protein which link on the present angle of the virus’s cell protein to the host cells and which in the circumstance is permitted to either penetrate the cell through in many cases the link on the CD4 (T-4) and are essentially destroyed by the cell on copulation with sugar and thymus derived T-cells within the surface of the host cell or as they enter the cell’s nucleus with their foreign DNA.
The HIV virus is proven capable of evading not only the host cells which it interrupts leading to early signs Symptoms of the viruses including Nausea, rashes, headaches, Kaposi Sacoma, which we would have learned by now, are the bi-product of a profligate Candidiasis from a depression involving a growth controlling factor such as other fungi or bacteria and in the case of Candidiasis – Streptococcus. That the latency of the Dormant viruses and bacteria after inception or ducking usually gives way in the holy communion of old virus entering the cell’s nucleus but with a foreign DNA – which is a not a entre-pot for any DNA material, for there the human DNA is reassembled and when a virus or bacteria bearing its own DNA permeate these cell’s complex they lead to a new form of infection.
But the latency passes and when more help is given to the body either through medication of chemical based replaced such as drugs (immunogenic) or through the natural support to t-cells and the body to fight the virus, the viruses and bacteria gradually diminishes its role as the b-cells gradually assimilate the basic elements of the once latent virus as part of the body’s immunologic; its vaccination or antibody proof. But in HIV, we are looking at the secondary phase of its activity, that when it reaches the human cells, it has already landed its own protective DNA from human beings itself and therefore predating the slicing by the cell. It is concealed and sent on its way by the human cells as part of the body yet it breeds and leads as a mutant in garment of new cell. It my theory that the expansion of the virus in the cells, that increases its demand on thymus by breaking the major sugar complex such as ‘lactose, b-galactosidase’ that aid the B-cells essentially leads to a collapse of immune system or the production of thymine and hence a replacement in medical exception by AZT.
Mario R. Capechi, Oliver Smithies (U.S) and Sir Martin J. Evens, 2007 were honored with Nobel Prize for Medicine in ‘Embryonic Stem Cells’ towards specific gene modifications, experimental models using knockout muse is proven important to help modify cells in the body. There are over 200 types of cells are altered in protean environment and ESC ‘embryonic stem cells’ – the matrix of the changes that take place after fertilization. It is during the fertilization that molecules carried over from a different parent are passed to the next generation. Above, it should be clearly stated that the first reproductive process in the life of all humans took place in the male testis and no elsewhere else. Using basic theme of these organizer theory, it means well if we can show that viruses at a very small unit compose as much functional life as the highest of creatures in terms of activity of neurons.
The work of these scientist and genetic engineering students, reminds me of enzymes in human body, especially the ‘releaser’ enzymes which modulates over a wide range of operational behaviors in the body. Some of operational changes are so common that it is very clear that any changes take place in the structure of an organism is due to the function of a particular enzyme. This also brings up the issue of stem cells and how they apply in deciding the particulars of tissue development, hence encourage its function through types.
Messenger RNA (Ribonucleic Acid) is for instance, a kind of the Nucleic Acid that sends all forms of information to Protein DNA, which trigger all forms of building protein in the course of human development, may continue to perform its function, leading to further development of protein due to the information received by the RNA and then the storage capacity of the Muscles and proteins becomes a very different matter. Why the issue of muscle development in Blacks specie or necessarily race, is due to the translation of excess or unused calories stored in the body of blacks, led to enhance bone formation or bigger bones and muscles, it is the quality of the protein of these Blacks, determined by the density of genes within their alleles which allows the DNA coding to continue, or at least break down at a very slower rate than others. The process of the translation of calories, and information is called Phosphorylation, where one deposit of genetic materials helps to develop the Muscles and Bones through series of ‘catabolic’ processes. It is this ability to store substantial information in the body in the many of the people and in the culture of the world that now dovetails much in the projection of the brain, with particular reference to speech and language.
But we take from their years of biological study of nature several fundamental facts, one, there is a great world of ours that involve the planet and which can essentially support itself and therefore constitute biosphere. There is what we can call ecosystem which is largely comprised of several species, involve several geographical locations such as the land next perhaps to a sea and so on to a hill, then perhaps a savanna grass land, all within reach of a specie and so on involves to some degree an ecosystem.
Where the support of life is buttressed by assorted types of specie seeking to survive their given environment, under perhaps a certain limited number of sources and interaction made possible, is regarded by biologist and experts as a community. What we can also indicate is that these ecosystems are not one but several groups of specie, but what is very important is the nature of the ‘community’ of specie surviving in a given ecosystem, for it seems that each human and external interference is likely to affect whatever is considered any form of balance in inter-community relationship.
Community relationship involves different species and animals executing their own wish for survival in a given biological construct. It involves a group, it involves a degree of interaction among the people in a population, and it involves a living condition. The issue of population and demographic, is so central to making of a community that a ‘population’ of animal in biology, is the arrangement of animals or organism of the same kind and in one geographic place. The given population of any animal is made up of individuals called ‘organism’ and a given organism of whatever specie and kind, is usually identified external and internal dynamics, the exoskeleton an organs, the tissues so to speak.
Tissues are what they are, a collection of cells and cells are systems of molecules and molecules are less reduced to units of physical sciences and chemical arrangement. So molecular biology is one area that summarizes the systems of classification and the field also explains why classification exists in biology, and why we have pecking order in the field. This field gave way to understanding DNA structure and the new studies of human genetic composition, Gene doping, Gene therapy, and of slicing and replacing of Genes that are either lacking in a biological body or genes that need to be supplanted to enabled a defense system that is outside of the body. This body has a way of protecting itself in any condition or any circumstances, much of these circumstances are derived from environment, as if the internal structure of any substance is similar to its.
Claude Bernard work on the species ability to survive its environment leads widen the conception of modern biology, that the issue of homeostasis, which is the study of physiological homeostasis, indicating that it has ability to survive all kinds of condition through the regulation of the internal energy so to speak. Here we have seen the effects of Claude Bernard (1813 – 1878) themes on ‘Milieu interior’ where the body by the age in which he lived regulated itself through what was termed ‘Homeostasis’. This ability of human body to regulate itself is not known science but was never considered entirely human without foreign ingredient for that to happen, and in the words of Bernard he states “The living body, though it has need of the surrounding environment, is nevertheless relatively independent of it. This independence which the organism has of its external environment derives from the fact that in the living being, the tissues are in fact withdrawn from direct external environment which is constituted, in particular, by the fluids in the circulating body.” The system he alluded to may be reduced to the fluids in the human body, some of which are pancreatic.
He is credited with pointing out that the several glands in the human body – though capable of existing on its own – may be affected with the more trying problems of temperature in the body of the organism to a point that its ability to secret liquids or enzymes towards a fully functioning body, is seriously dependent of what other organs of the body is doing. An example of this kind internal regulation is the direct ability to preserve batches of E. Coli bacteria under 37 C temperature. The timeless work of Joshua Lederberg on the responses of the E Coli to Sugar and the survival of the E Coli in the human earned him Nobel Prize recognition. There is hardly anything new about E Coli but it’s representation in dealing with HIV especially the role of enzymes and how they are prepared and easily denatured on certain exposure, perhaps why the HIV virus itself easily denatures on contact with some forms of sunlight, how E coli is especially predisposed to breaking up what Jacque Monod described as ‘two headed bacteria’ or perhaps a ‘retro-virus’ bearing reverse transcriptase, entertains the reasons why preventing the slighting of the slighting of proteins or nucleotides and the control of these processes through the use of protein inhibitors or protease and the relapse to reverse transcriptase in the three cocktail has routinely occupied the minds of scientist. Identifying the cells that control some
The Chapter was destined to be written and the final solution begins from where we started….
There is something about the Medical Institutions and the Act of medical discoveries that can plunge an entire world of information into some abyss until perhaps redemption. All the breakthroughs in science and technology need not be rehearsed as a consequence of these long years of experiment and studies, leading to disasters of all types and sometimes with some degree of consequence. One man whose theory concerning the problems of perpetual error and why institutions carry on with these mistakes is Joseph Greenberg in his dissertations about language and human dispersion theory, theories well evident by the Luigi Cavalli-Sforza. Mistakes can be conceived by any number of institutions and can be transferred from one form to another and until a breakthrough; it survives some of the assumptions in business and elsewhere. The advent of HIV at least in the least in the last 35 years is no different from this kind of problem, especially those of Polio which has given us all the headache known to us.
That a thing and perhaps a sickness such as paralyses from Polio eluded the frontiers of sciences for at least 40 years in spite of the breakthrough by the Karl Landsteiner on A, B, O on the bone marrow and the brilliance of a certain Jewish immigrant by name Simon Flexner who for his sake and for the need of medical research that they developed the Rockefeller Institute in New York. These men including those took umbrage under his leadership, (1) Herald Cox (2) Max Theiler (3) Isabel Morgan (4) Thomas Francis (5) Tom Rivers (6) Peter Olitsky (7) Albert Sabin, names very familiar with us in Virology and the culture, and like in many open sources these are champions of medicine for many years in vaccination and early attempts stem cell research. The book that throws some light on the history of these few including the familiar Max Theiler who succeeded in growing a Virus in the brain of mouse is called Polio; An American Story, by David M. Oshinsky (05), we should be able to quote from this book, at least in gainsaying on some of the assumptions about the connection between Polio and HIV, where the author made some medical blunders no more than the ones that Merck made about the unknown dynamics of the human immune system.
But in Oshinky’s ‘Polio’ story we are privy to his citations describing an important figure in fight of Polio by name Karl Landsteiner that “At his Laboratory in Vienna, Landsteiner produced an emulsion from the Spinal cord of a boy who just died of Polio. He passed the liquid through a porcelain filter, injected the contents into the stomach of two rhesus monkeys, and waited to observe the result. It didn’t take long; the monkeys proved to be wonderfully susceptible hosts. Both succumbed to Polio, their spinal cords showing much the same damage that had occurred in the little boy. The Polio virus had been isolated.” The process of extracting a virus would in future be that complicated but they follow the same process, yet the intentions behind rendering the piece in spite of the Polio is taint the discourse with the bone marrow incident regarding the treatment of immune deficiency syndrome that much effort has been put in to help the victims of the AIDS whose bodies are racked by the virus by chemotherapy in removing much of the bloods in the spleen and bone marrow of the affected areas or areas of interest, and using a foreign entity and bone marrow try to restore the blood of the patient in a process that is similar to cancer treatment yet they get worse and worse. The point that HIV is at least for now a blood borne Virus does not
If the virus is fed through the mouth the victim hardly suffers any special injuries and any specific inductive injuries but when the Virus is fed through the nose, the reactions were very fatal. In fact the mode of infection which are so believed as the same and similar to Tuberculosis which infected people through the nose and breathing, cursed severe reaction in the body of the victims particularly the monkeys, may have given some reason that the mode of penetration of the virus was similar to other agents of the body.
David Oshinsky writes that “No one found a way to block poliovirus from entering the body or to neutralize it with drugs or chemicals once it got inside” For many years the conception that the nose was how the virus entered the body proved frustrating to scientist and in the image of Simon Flexner who help to carry out major reforms in virology, there was hardly anyone to challenge the basic assumptions. There was something else, apparently the reason why the mouth feeding of the virus did not convey any particular kind of adaptive meaning, is that the monkey used for these experiment is called Rhesus monkey. Its ability to mount immune response depended on many things, in part for the silaic acids which are contained in the body and are presence in the nose and nasal cavity, exfoliates its existence and as someone theorized, many people did not know why we couldn’t stop the virus from entering the body. It would seem that it was only through the nose that such penetration of the body was possible.
The story on how it was discovered that other primates reacted differently to the virus when fed from the mouth is not clear, but the opposition of Flexner to the use of these primates proved that it was a well-known fact or suspected as such that a particularly kind of monkey acted differently when the virus is fed through the mouth. The rest were victims of the same thing. For that reason, the understanding that the route of the virus was from the alimentary canal and not the nose or at least more than nose, proved a damage to Flexner’s theories and became a point of rally for all scientist. This new knowledge is so critical to further enhance the experiment on Polio viruses that it led many scientists to shift their attention from monkeys to chimpanzees.
Oshinsky put it kindly that “if Polio virus entered through the mouth and worked its way down the digestive tract, then it must travel through the blood before entering the central nervous system. If so, a vaccine designed to raise anti-body levels in the bloodstream would be able to neutralize the virus before serious damage was done.”
From this development, they were able after almost forty years of the studies on Polio virus to now learn how the virus develops and what makes it work and why the virus became a hit for the rest of the scientific America. At least Scientists were now able to focus at (early infection) and the blood stream was the place. In the words of John Paul, “It meant that small amount of virus which invaded the blood could probably be overcome by relatively small amounts of circulating anti-body, and by this means could be blocked from gaining access to the central nervous system….At one fell swoop, the problem of immunizing man had been rendered easier than was expected.”
Among the first investigators to look at the virus in previous and neglected blood samples was a certain Dorothy Horstmann, who was a member of Yale crack Polio Unit team of invested much of her time in looking at blood of the victims that came into the hospital from the 1943. A basic line should include David Bodian and his group; she was not the first or the only one that looked at the blood of the victims that were infected by the Polio virus. And the blood became very central to the point of demonstrating from the stored blood of nine year old, that unless the virus was not in the system and in the body already, there was no way of knowing unless she got sick. That it was only on this account did any change take place in the body at all, that as soon the blood realized that it had a disruption in its system, proteins and folded inwards and then the attack on the nervous system which is primary to the virus.
If fed through the mouth the virus could invade all the stomach and reach down the body where it profligates, but majority of time and according to several practices which are done, the virus hardly makes it into the blood stream in large amount when induced through the mouth of some monkeys and ended up creating paralyses leaving antibodies which has neutralized the virus. The whooping size of his academics raised the tempo of suspicion towards Apes, Chimpanzees, and Monkeys as probable origins of the Virus which eventually came in with their mutations in human and hence nearly justified the all kinds of experiments in Congo. I must confess I have only casually flip through the books and do not intend on writing on what clearly obvious from his missive that the general academic consensus favors a Spillover from Monkeys and Chimpanzee into Human beings.
Philip Alcabes (2010) Dread book that attempts to consider what the early CDC workers attempted to achieve with HIV and how some of the jokes about HIV did not shy from the social stigma of those who were called freaks or in the 60’s bums, who suffered all kinds of malfunction in the body and were essentially housed elsewhere till perhaps redemption which sometimes arrived too late. If it is not impossible to locate this item elsewhere is because of alternate historical account of outbreaks in City wide location, point to breakthroughs that gave medicine a new and profound meaning. In his chronicle on HIV he pointed to an early date made by CDC released in September 1982, that “Homosexuals or bi-sexual makes – 75%, intravenous drug abuser with no history of homosexual activity – 13%, Haitians with neither a history of homosexuality or intravenous drug abuse – 6%, persons with hemophilia A with no other risk factors – 0.3%, and persons in none of the other groups – 5%.” Whereas anyone could get the virus he argues, HIV was simply the most dreaded thing partly for the fact that there was no cures at the time, but largely for the social stigma that was associated with it. Many of the Black and Hispanic in New York did not see it as very present and dangerous virus capable of infecting black as well others, and they loathed the virus as a white-man disease.
But before long, it was gradually shown that the virus began as a series of carefully planned conquest over the host immune system, and after a decade of the virus of the human it degenerates into something else.
For if Blacks were gradually gaining up to others despite being one of the smallest groups of minority in New York in terms of new cases on HIV, it was due to the problems of information and reaction, which do not add to anything useful.
For Asians and Africans, they were largely hung over on the transfer of the new virus emanating from Gay Communities in New York to other parts of New York and elsewhere, and since they loathed these communities; they are easily vulnerable to the viruses. Although New York in times past may have entertained the arrival of diseases and other infectious disorder, it has lead the fights against dangerous diseases, against Polio and Influenza, against diseases; both airborne and waterborne. The City is hive of visitors with long term view of the City and travelers for other reasons and immigrant population since the 18th hundred has continued to sprawl till very recent days.
New York downtown has no particular architectural, the immigrant populations; Irish, Italians, Jews, Africans, Caribbean, North and Central America, and other income capable brackets were primarily concerned with their own survival. Although the immigration continued in New York by Europeans, it helped to form some of the assumptions about new diseases and epidemics, to a point that it can be said that studies about the early diseases in New York in the last 100 years or so were mostly derived from reaction to outbreaks such as Chicken Pox (Varicella), Pertussis (Whooping Cough), Pneumococcus, Hepatitis A, Hepatitis B, Rotavirus, Influenza, Meningococcal and some variety of human papillomavirus. In a sense some of the assumptions about these diseases made outsiders temporary targets for reasons of their own.
The Polio virus was one of those outbreaks where a strain from African monkeys was very necessary in understanding the pathology of Polio which Flexner believed was generated from stomach to the body or through digestive tract – in essence it was ingested. Many of the experiments at the very beginning had to with mouth feeding of some of the creatures and primates – especially monkeys were fed through the mouth with strains of Polio virus and the end was not to the interest of the scientist. The main point is not the process of profligate Polio virus but on why it was necessary to ingest the various from the beginning and why the issue of blood pathogen proved a different and difficult point to redress. Look at it differently, when it became very clear that the Polio passed through several processes and especially the blood, the science committee was more than ready to handle the Polio mellitus once and for all.
Secondly, if the mentioned virus-ridden diseases and conditions, especially Influenza and Spanish Flu for instance of the 20th century A.D, were considered from purely medical and biological point of view, they show patterns of infection and host-DNA which alters the destruction of the infection process of the virus, some produce fever others with the same viral infection may give similar but different infection in the body. The immigration population who make it to New York where left to places such as Randall’s Island, New York, a place which as the repository for those dead or dying. Of course they naturally remain quarantined saving for instances of Polio and viral strain of its culture.
The modernity of New York as now and then appears on the world map and its visible schools of medicine was not always the case, for at least we can set our eyes on the formidable FDR days, whose efforts as Governor of New York and eventually president proved a watermark for the attitude of the public to issues of health. It would not mean that Harlem River drive heading the F.D.R was named after for political reasons, but the combating of Polio by forces affiliated with his office such Bob O’Connor makes the faithful date of CDC recent as they provide the necessary tools towards the growth in health we have seen over the years. But needs be mentioned that a lot list of all the breakthroughs of sciences in the United States and in the world did not arrive by idle conjecture, did not arrive by efforts of any one group such those for instance at Rockefeller Institute which has fielded and trained more competent and decisive virologist in the last formidable century, more than nearly all institutions anywhere in the world.
Perhaps the Pasteur Institute of Paris or other Schools of interest in Massachusetts; Harvard, etc., which though perform its function along the elite schools of the country, cannot in itself expel the contribution by other schools either directly or indirectly influenced by Rockefeller Institute in the last century.
This will not mean that schools such as City College of New York with as many Nobel Prize winners as Yale is to be taken away, it shows however that the merit of open culture and attitude to this merit widens on the even the smallest avenue of possibility that what works in one area, may not apply in other cases. It will be useful to point that the Cold Spring Laboratories in Long Island maintained an open culture and relevancy of attitude to science from the days of its founding by Watson and Company to nearly all combating of new virus which CDC is particularly known for. That will add to the assumptions that the failures over the years to deliver on HIV may be due to the fact that it was believed to be disseminated through deviant sexuality and the encouraging the scorn that it was created by God. But if half of what learnt over the years and at least in the opening heroic search for cure at the beginning was never replaced or transferred from one community to another, we may have in my view – purely in my view – put a final end to the Virus.
While it is easy for me to accept that giant steps in Medicine has failed in generating final solutions for HIV, it serves then as well now as an example for what may have transpired between Polio Virus and the arrival of the scientist who ended the whole sage. In areas I succeeded might clearly interest you with the fact that I spent 2 years studying Harvard Medicine for fun of it. And in the last returning decade and a half have spent hours of a given day on History, Anthropology, and generally studies human genetics. Majority of these studies show it’s relativity to HIV and the cure for immune deficiency syndrome prove a lengthy stay for reasons of their own, to a point that some of the conclusion vary in its results and the end point was a question of some understanding about viruses and its evolution. This aspect of our understanding of biology and chemistry is very important given the very reason why vaccinations seem to have failed.
Barely a year ago, the argument about the SVO40 virus supposedly from Chimpanzee and the Polio virus seem to have stagnated between Chimpanzees and human immunogenic viruses, which may have resulted the strain from Polio considered a leading item to HIV. But this argument in all its forms had to be dealt with, perhaps decisively given the basic premise of HIV infections and its pathology. Put it differently, there is no connection between Polio Viruses and HIV, and there is no link between immunogenic viruses which infect primates and humans saving the issues of the patterns of infection and the chief cause of the agents. The example about the slow viruses and oncogenic viruses are especially important largely for leading but misleading line of reason about HIV and the very knowledge of viruses and immune deficiency syndrome.
Looking backwards to some of the stories from Bronx and from parts of White Plains, New York in the early 90’s, there is hardly anyone who knows what the virus was all about and what its problems anywhere. It was known to be deadly, known to remain dormant for a long time, to be conversant with Homosexuals and with illicit drug users, where they speculated that sharing needles was very dangerous because of the dangers of blood contamination. Special classes are taken to handle blood and the secrets keep so tightly about victims that even some of the workers were placed on a need to basis. On a special basis as well, there are reference to Russia and the events of Cold viruses, including period of long epizootic and Moritz Kaposi (Russia) associated with description of what eventually considered Sarcoma, and pox related virus sickness.
It will seem also that the comparison between the Lentivirus that Montagnier is associated with is not unknown to Gallo, promotes only two possibly arguments that Robert Gallo were looking at the comparative physiology of the primates and the humans, their gaps in defense mechanism and whole comparative physiognomy, that he believes in lieu of Rockefeller Institute and their historical breakthroughs, that a similar virus if discovered in the primates can lend a pair of eyes to those of humans.
The second reasons are that he and his group may have believed upfront that the virus essentially came from Africa. It is only reasonably reassuring that Interleukin-2 associated thymus which Montagnier emphasized has its reasons, based perhaps of Claude Jasmine Chermann.
When we look at the structure of the protein from sources totally available to us, the use and eventually the abuse of Gallo’s strain resulting in its isolation of the human version of the Zairian Strain, is said to be oncogenic virus, means that it is cancer causing, will also point to the fact that over the last returning decade of the search for HIV and its cure was sentenced to a goose chase, point must be made that the strain however oncogenic could not connected to human cancer, though the virus when triggered delivers according to its purpose.
Therefore a connection between the cancer virus and human immunodeficiency virus were test that led to wrong conclusions, for if HIV in of itself could infect monkeys, a kind zoonotic trans-infection would be possible among the humans. Looking at the conflict in the early years between Gallo and Montagnier, it is becomes gradually clear that Montagnier or the house on which Montagnier is based would have collapsed, were it not for the fact that he did specifically mention that he used the Interleukin-2 protein induced virus to isolate the HIV virus, suggesting that he was right that the virus called HIV or initially a LAV virus was different from Gallo’s Virus.
For the similarity and differences between Gallo and Montagnier, it will be common sense to show that cancer is the bottom line in whole argument, while the Gallo cancer causing virus is different from Montagnier is perhaps due to their specific origins. Although there are other viruses that trigger the creation of mutants, the rate at which we notice the differences between the two scientists is what their viruses do inside the body.
HIV can be called a kind of cancer; perhaps blood cancer given the long held observations of people with the virus and may have been the motivations behind the use of cancer agents with direct reference to the blood.
But it is the blood that matters, what happens to the Red Blood cells over time which ends up affecting white blood cells or CD4 counts over time. A dip in the CD4 counts eventually comprises the body’s defense systems. We are now certain that AIDS patients die from Opportunistic Infection (OI) and not from HIV itself. Looking at the history of HIV from these schools will arm with some basic understanding on why emphasis on thymine very central towards the survival of the patient, and why most efforts in correcting the reverse transcriptase did not perhaps lead to any new grounds.
Here it will be rewarding to show that mycobacteria is not a new name in the market, it is has been and for many scientist for instance Lynn Marguilis and her colleague Dorian Sagan, have given some academic devotion to the transformation that take place in the life of a bacteria and how these mutational changes, from one area of the chromosomal to another adds meaning to what is now called Epigenesist which..., and which Adesinine and Guanine based protein building on a three level phosphorylation within the cell and through diacyglecrol perform separate respiratory function relative to the ions of the surface, where a short and misconceived attraction and relapse duration(cell respiratory on the Golgi body) can affect the false release of information and trigger event reaction from the cell are based on some role of oxygen.
If we recall briefly the experiments of Oswald Avery on pneumococcus, there is an express that he defined about Deoxyribonase Nucleic Acid (deoxyribonucleic acid) there he emphasized thymine as operand towards the creation of new DNA.
Some multi-celled organism living in the gut of say Cow or in its intestines, which are naturally used for the reproductive processes of a milk (bi-product) are not normally known to be destructive, may remain friendly in the gut and intestines of the Cow or other mammals until the frequency of the cells or immunogenic is comprised….It is these two viruses that are equally significant in the defenses and failures for and against HLTV virus which are generally oncogenic such as the ras and abl and to some arguable degree yes genes in blood and pneumonia related cases can be represented as viruses received from several range from bare-back viruses such as mycobacterium, particularly Avian which is a Sars virus which is respiratory based virus and in like viruses or multi-cellular organism and their viruses….
Flossie Wang-Staal researched with great success of the structure of HIV, and it was the knowledge of the transcription factors acting on the HIV, especially in the introns and enhancers, the terminations point of the Amino sequencing that provided the base-board for developing AZT, which implies the phosphate roles of thymine and was set then without knowing against a alu genes. The marking in terms of the transcription factor largely because HIV is replicated at the right of the LTR, but seem by its transcriptase to have perhaps started its origins at the left of LTR.
That it is no use and cannot really affect humans as such the placement of the virus at whatever angle and its conjugation to the nearest human cell which replicates at the right of LTR as with Amino Acid, prove to be well meaning for a healthy life of a cell, but this key location could also transduce a mutation leading to cancerous edifies or creation of mutants. This in-of itself can induce cancer causing deficiency in human beings and has means and ways of expressing itself in human beings as primates – with or without due respect to the Alu genes.
For all intended reasons we presuppose the methyl alu genes is a jumping genes that is not insubordinate to mutations, and should be classified as mutagenic. Alu genes are relatively twisted does not mean they are retrovirus or retrograde, but there are reasons why these twist, they reveal a different version of the genetic DNA especially among Africa Blacks. It is suggested that this is part of their evolutionary past is prove to the causal link between the past Great Apes and the present but these are alu are not formed in the Great Apes and not prions or dangerous.
The man who whose theory on defective proteins and prions, whose work transformed our knowledge of prions is Stanley Prusiner. Whether the constipation of the alu genes or the jumping genes that confirms Stanley Prusiner (U.S) long lived Noble Prize on Prions as infectious proteins, we are clear that infectious proteins are mutagenic and does not inspire a transformation from one form to another, a saturated argument anyone can make saving for the vast implications in phage studies.
For sure if in more recent times, that Arjit Varik and Elaine Muchmore in trying to adapt a new drug to enzymes working to oppress the profligate of HIV did not award much help, there is then something wrong in the process, a misleading grasps of the fundamentals of molecular biology or in recent times, RNA sciences. “By 1998 Varki knew why we were peculiar; a 92-letter sequence was missing from a gene called CMAH on Chromosome 6 in human beings, a gene that codes for the enzyme that makes GC.” ‘Right in the middle of the sequence was an Alu genes = ‘Jumping genes. “So sometime after the divergence of the human and chimp lineage, this Alu had done what it does best, which is to jump into the CMAH gene, swap places with the older Alu, and accidently remove the 92-letter chunk of the gene while it was about it”
‘Throwing stitches’ using his exert quotations, Matt Ridley stated that the “Hox genes are the recipes for proteins called “transcription factors”, which means that their job is to “switch on” other genes. A transcription factor works by attaching itself to a region of DNA called a ‘promoter’, where IGF2R gene on Chromosome 6 ‘Premature damage to the brain or late development…
AZT as described by many experts is cell mediated immune response where AZT is incorporated into the host cells, DNA, and as Irwin Sherman suggested it is shown to be introduced in some numbers in the DNA which is set to clarify what Peter Deusberg mentioned that it actually tampers with your human DNA, whereas the Factor VIII mentioned by Deusberg is not exactly anomalous may prove to be relevant to Hemophiliacs…..
On AZT a ground breaking theory, we have noticed the work of other experts such as M. D Grmek (1990; translated by Russell Maulitz, Jacalyn Duffin), that points out the evolution of the disease in six hierarchical stages and according to the maturation of its protein, which for the author reflected “the chorological and biological status of infection…” and it is A, T, G, and C, that make up DNA…..3-azido-3’-deoxythymidine – or AZT…., the Antigen-presenting cells and whose Human leukocytes, Storm trooper T cells antigen (HLA), Viral antigen, T-cell receptor (TCR) and in one major combination shift from basic complex to defense mechanism – more like the age of protein, with age protein perform different function in human body.
Dani Bolognesi, the whole structure of HIV protein fell, with one particular emphasis of the gp120 envelope glycoprotein. This gp 120 proved a deciding mark in the renewed assault on HIV sometime in 80’s and it revealed considerable presence of what he called ‘main proteins’ (P24/25 inside of the protein box, and gp120 and gp41-43 outside) whereas some of the proteins are well to share comparative similarity with sooty mangab1ey (cercocebus atys) which carried a strain of the virus (STLV – IIIsmm) inside.
In relation to these strain of viruses, there are lengthy….Grmek as one the foundation members of the war against HIV mentioned understanding the cleavage enzyme that was delayed in the orchestration of the CD4, and the primary.
Daniel Bolognesi continued that ‘To this end, biological modifiers of the T-lymphocytes, such as interleukin-2(IL-2), hormones derived from the thymus gland, or thymomimetic drugs (DTC, commercial name imnthiol), were tried, as well as transfusion of HLA-matched lymphocytes or even bone marrow transplantation.”
Emphasis – even after some decades on HIV is thymomimetic drugs which sometimes prove poisonous given its
“The first of these products autoimoniotung state or HPA – 23 (so named because it was the twenty – third heteropolyanion synthesized by chemist Gilbert Herve and Andre’ Teze), was known ever since 1974 work of Claude Jasmine Chermann as an inhibitor of reverse transcriptase in the retrovirus responsible for murine leukemia and sarcoma. Chermann studied its action on the AIDS virus. HPA -23 inhibited the activity of LAV reverse transcriptase in vitro.” And for this breakthrough studying the reverse transcriptase is greatly advanced, has dominated a lot of studies in this respect excluding gene therapy in very recent terms.
The impact of HPA 23 in reversing elemental LTR Amino replication center including the P. 53 for cancer with respect of the age of the cells (telomeres) never papered as accurately as the promise of reversing the reverse transcriptase of probably trapped bacteria prophage in the evolving chromosomal based (HIV) Viral RNA. The understanding that genes sometimes trip the activity of Amino acids is a well-established and grounded biological induction, especially manifest in the attempt of showing the physical-chemical properties of cells and their lopes which on the surface are controlled by the transport of energy information and by default oxygen.
Although the uracil (urea) is the set aside as the element that it responsible for the beginning of the process of all biosynthesis with look-alike bases comparable to phosphate-methyl 5, most common of which is thymine, it is for this that elements containing uracil with the 5th position as bromo-uracil usually translate in the second stages of the sugar complexes wrong information, since the mutant protein or bacteria that break them the coupling polysaccharide is turned off or at least considered mutant, and therefore cannot profligate at the essence of enzymes that dissolves sugar complexes.
This alone along with activities that result from the excess lysogenic activity does affect the replication of Amino Acids, may help in editing some of the information between RNA and DNA, may repay false RNA to RNA, but may not probably trip the genetic activity resulting from the rest of body but eventually affecting HPA 23. In essence, this attempt by Chermann to inhibit the profligate of the VIRUS through arresting the activity of the binding reverse transcriptase, may involve the artificial introduction of thymine – which essentially aids the cells to control the activity of dictated foreign antigen.
Michael Bishop and Harold Varmus discovered that “virus-encoded oncogenes originate in eukaryotic cells.” But it will be the Gallo team that will make the better of this theory, and if in the decision which lend meaning to how some of the theories of oncogenes that dominated the early and later stages of Baltimore is placed on the same context as Gallo as he presented some of his assumptions.
That “The HIV dissidents could see two fundamental problems; HIV was a retrovirus, meaning it should not kill the cells it infected, and the virus could barely be detected even in late-stage AIDS patients”, Deusberg (2003) which threw its own light in the context of well understood realities of the Virus and why it remains part of the human body in spite of the drugs released to deal with it…..
Although Deusberg and company need to place some faith in the assumptions raised by the two leading schools of Gallo and Montagnier, the later holds more promise but Gallo may have struck an ideal comparative between the operational dynamics of a leukemia virus – perhaps in the discipleship of Stanley …..and his prions which are destructive proteins which also have origins somewhere else, and still for reasons not exactly clear is short of the right stuff in fishing the left and right of HIV when the CCR5 is knocked out in experimental relocations of the…..
In the event that some worrying castigations on the number of failed vaccines – at least well-meaning 20 vaccines - can be left to the primitive carousal of a CD4 protein inhibitor by name nef so named by the company that identified the proteins which HIV DNA based do not produce, it may not escape our mind that the intrepid connection between the SV…..In one Deusberg’s exertion’s “AIDS is not a disease. Instead, the AIDS Syndrome is a steadily growing collection of (currently) about thirty “previously known” (old) diseases.
Surprisingly in view of their notoriety for AIDS definitions, It is true, however, that the incidence of AIDS diseases has increased dramatically in the 1980’s as intravenous drug use has increased and as both the consumption of recreational drugs used as sexual stimulants and the use of AZT as antiviral drug have increased in male homosexuals….”, may true to a large possible extent, that the problem of HIV viruses, as they apply to Deusberg theories, is not necessarily the lipid bi-layer of its outer shell which duck the human cells containing CCR5 receptor, which also promotes the second attachment between the Virus and the ducking CCR5 from the HIV virus.
