Wednesday, May 24, 2017

HIV (5)

mr., Onwuka

There are so much that enter public discussion on HIV, but half of the standard procedure for handling the virus – beginning with prescription for HIV Patient cover two major categories, the Nuke and None Nuke and in the words of Magic Johnson, there are more than 22 specialist products on HIV, including AZT – (Zidovudine or Azidothymidine) approved in 1987 by FDA, used on farm animals, primarily popular in the 90’s, popular in New York and renown for poisonous, and remained for a long time the major problem with Food and drug administration. But from the sciences involved in understanding HIV and the treatment that followed, these products types are probably similar in essence and cover at least three major aspects of the HIV treatment, from inhibiting the growth of the Virus to the aiding the CD4s in its attempt in reducing the efficacy of the Viral load at any level of its existence. The last basic determinative of the designer drug is suffocating the maturity of the virions into adult virus – delaying its destructive adult stages. Whatever may be the nature of the Virus and the attention of drug companies, the attempt at inhibiting the progress of the Virus and the use of AZT in normalizing the function of the body or hormones in the body and its CD4 responses will only delayed the end. It is the expectation of medical profession that if the Baby Virions are kept at the lows level of maturity, it may prove less destructive to the system or the body, proving in certain cases that the drug may lengthen the life of a victim. The earliest patients were known not to have died from the virus itself suggesting to scientist that perhaps that preventing the HIV from profligate activity was more rewarding than the cure. What exactly killed HIV patient – assuming the HIV was not lethal and the virus slow in its destruction? The patient dies from other infections other than self was one of the central puzzles that defied the earliest years of the pandemic. The challenge is how to overcome the pandemic and to end the most demanding infection other than cancer. There are great many stories regarding the behavior of AIDS patient. Some of the dread over HIV was due to its presence in “FECES – Nasal fluid”, in the Saliva of the patient, including – ‘sweat, tears, urine’, some of the cases of the dread involve use of “Urine – Vomit, “Vomit – slight chance with blood on it”, and other body fluids (1) Amniotic fluids, (2) “cerebrospinal fluid” and (3) synovial fluid”.


To manage the cycle of information which does not die easy – especially with the pandemic that took American by storm, some of the early claims about earlier (viruses) or infections need to be drawn, part of which is how and to what extent the virus defies the system. Perhaps in this account, some of the general definition on the virus leads us to emphasize the commitment of its earliest scientist to finding a cure. There is nothing displaced about champions such as Watson and Crick, for instance, these men were alive at the time of the pandemic and struggled to provide the answer but how the virus took a shine off their brilliance has not been well discussed, above all, how some of their drives with HIV provided paved the way for other experiments. The shift in the focus of the study of HIV is perhaps due to other civil strife. It is worth the time to return to the early years of the pandemic and pull straws on what the Scientist did, when and how. Accounts of the DNA discoveries (A) James Watson (b) Francis Crick is still popular – so also the story of the Alpha Helix, the accounts on Haemoglobin and the accounts of Linus Pauling including his work on Sickle Cells, HPA 22 Insulin (Diabetes), Insulin – including the work of Jacques Monod and his E. Coli Phage Diabetes – some of which is reach back to Oswald Avery (S-strain, Streptococcus, E Coli Phage Virus,..) part of which is the story of Vaccination leading in case to John Enders, James Salk, Albert Sabin, Tuberculosis….The standard techniques for studying new pandemics is not unknown, but the relevant questions are still useful, that is, what happens or happened during periods of epidemics such as flu-virus? How does that relate to pandemic such as EBV or in our studies, HIV? How does the story of Polio and period of cold virus prove a point of interest for those who ventured into Africa in search of the origins of HIV? Since the scientist driven from their home land, and write back to the States, where these scientist interested in major themes on HIV or he experiment with vaccination proved a point for evolution and studies in anthropology. HIV is argued to have origins in other creatures and remains for many of us a point of dissent. The theory has political stay, and there are few believers in that such theories on Zaire strain, may be correct, fewer will accept that perhaps the African dissent on the origins of HIV is perhaps misleading - if not untrue. The role of enzyme in the blood is important – the role of oxygen in the blood is also important, but the link to thymus and link with E Coli phage bacteria or sugar mulching prophage may yet gain acceptance. The profligate behavior of E.coli naturally involves the reduction of sugar – they feed on sugar molecules thereby preventing the normal molecule structure of the Carbon ( ) DNA especially thymus.



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